BE800905A - Ajmaline glycosides - as antiarrythmic agents - Google Patents
Ajmaline glycosides - as antiarrythmic agentsInfo
- Publication number
- BE800905A BE800905A BE132260A BE132260A BE800905A BE 800905 A BE800905 A BE 800905A BE 132260 A BE132260 A BE 132260A BE 132260 A BE132260 A BE 132260A BE 800905 A BE800905 A BE 800905A
- Authority
- BE
- Belgium
- Prior art keywords
- ajmaline
- glycosides
- antiarrythmic agents
- acyl
- antiarrythmic
- Prior art date
Links
- CJDRUOGAGYHKKD-UHFFFAOYSA-N Iso-ajmalin Natural products CN1C2=CC=CC=C2C2(C(C34)O)C1C1CC3C(CC)C(O)N1C4C2 CJDRUOGAGYHKKD-UHFFFAOYSA-N 0.000 title abstract 2
- 244000061121 Rauvolfia serpentina Species 0.000 title abstract 2
- 229960004332 ajmaline Drugs 0.000 title abstract 2
- 229930182470 glycoside Natural products 0.000 title abstract 2
- -1 Ajmaline glycosides Chemical class 0.000 title 1
- 230000003288 anthiarrhythmic effect Effects 0.000 title 1
- 125000002252 acyl group Chemical group 0.000 abstract 2
- 125000003563 glycoside group Chemical group 0.000 abstract 2
- CJDRUOGAGYHKKD-RQBLFBSQSA-N 1pon08459r Chemical compound CN([C@H]1[C@@]2(C[C@@]3([H])[C@@H]([C@@H](O)N42)CC)[H])C2=CC=CC=C2[C@]11C[C@@]4([H])[C@H]3[C@H]1O CJDRUOGAGYHKKD-RQBLFBSQSA-N 0.000 abstract 1
- 150000004820 halides Chemical class 0.000 abstract 1
- 229910000108 silver(I,III) oxide Inorganic materials 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
- C07H17/00—Compounds containing heterocyclic radicals directly attached to hetero atoms of saccharide radicals
- C07H17/02—Heterocyclic radicals containing only nitrogen as ring hetero atoms
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Engineering & Computer Science (AREA)
- Biochemistry (AREA)
- Biotechnology (AREA)
- General Health & Medical Sciences (AREA)
- Genetics & Genomics (AREA)
- Molecular Biology (AREA)
- Saccharide Compounds (AREA)
Abstract
Cpds. (I): (where R1 is H or acyl and R2 is a glycoside or R1 is a glycoside residue and R2 is H or acyl), are prepd. by reacting ajmaline or its 17- or 21-acyl deriv. with an O-acylglycosyl halide. Thus 21-acetyl ajmaline-17-yl heptaacetylbromolactone in the presence of Ag2O.
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| BE132260A BE800905A (en) | 1973-06-14 | 1973-06-14 | Ajmaline glycosides - as antiarrythmic agents |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| BE132260A BE800905A (en) | 1973-06-14 | 1973-06-14 | Ajmaline glycosides - as antiarrythmic agents |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| BE800905A true BE800905A (en) | 1973-10-01 |
Family
ID=3841996
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| BE132260A BE800905A (en) | 1973-06-14 | 1973-06-14 | Ajmaline glycosides - as antiarrythmic agents |
Country Status (1)
| Country | Link |
|---|---|
| BE (1) | BE800905A (en) |
-
1973
- 1973-06-14 BE BE132260A patent/BE800905A/en unknown
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