BE798663A - Fermentative deacetoxycephalosporin c prodn - with penicillin-n-producing microorganisms - Google Patents
Fermentative deacetoxycephalosporin c prodn - with penicillin-n-producing microorganismsInfo
- Publication number
- BE798663A BE798663A BE1004995A BE1004995A BE798663A BE 798663 A BE798663 A BE 798663A BE 1004995 A BE1004995 A BE 1004995A BE 1004995 A BE1004995 A BE 1004995A BE 798663 A BE798663 A BE 798663A
- Authority
- BE
- Belgium
- Prior art keywords
- nrrl
- deacetoxycephalosporin
- penicillin
- prodn
- fermentative
- Prior art date
Links
- 244000005700 microbiome Species 0.000 title abstract 3
- MIFYHUACUWQUKT-GPUHXXMPSA-N penicillin N Chemical compound OC(=O)[C@H]1C(C)(C)S[C@@H]2[C@H](NC(=O)CCC[C@@H](N)C(O)=O)C(=O)N21 MIFYHUACUWQUKT-GPUHXXMPSA-N 0.000 title abstract 2
- NNQIJOYQWYKBOW-VMAXQDLPSA-N deacetoxycephalosporin-c Chemical compound S1CC(C)=C(C(O)=O)N2C(=O)[C@@H](NC(=O)CCC[C@H](N)C(O)=O)[C@H]12 NNQIJOYQWYKBOW-VMAXQDLPSA-N 0.000 title 1
- 229930186147 Cephalosporin Natural products 0.000 abstract 1
- 241001619326 Cephalosporium Species 0.000 abstract 1
- 241000135254 Cephalosporium sp. Species 0.000 abstract 1
- 241000190562 Emericellopsis Species 0.000 abstract 1
- 241000018673 Emericellopsis sp. Species 0.000 abstract 1
- MIFYHUACUWQUKT-UHFFFAOYSA-N Isopenicillin N Natural products OC(=O)C1C(C)(C)SC2C(NC(=O)CCCC(N)C(O)=O)C(=O)N21 MIFYHUACUWQUKT-UHFFFAOYSA-N 0.000 abstract 1
- 241000673239 Pachyphlodes carneus Species 0.000 abstract 1
- 241001236817 Paecilomyces <Clavicipitaceae> Species 0.000 abstract 1
- 241000754833 Pochonia chlamydosporia Species 0.000 abstract 1
- 241000122799 Scopulariopsis Species 0.000 abstract 1
- 241000915973 Scopulariopsis sp. Species 0.000 abstract 1
- 229950008644 adicillin Drugs 0.000 abstract 1
- 239000003242 anti bacterial agent Substances 0.000 abstract 1
- 229940088710 antibiotic agent Drugs 0.000 abstract 1
- 229940124587 cephalosporin Drugs 0.000 abstract 1
- 150000001780 cephalosporins Chemical class 0.000 abstract 1
- 238000012258 culturing Methods 0.000 abstract 1
- NNQIJOYQWYKBOW-JWKOBGCHSA-N deacetoxycephalosporin C Chemical compound S1CC(C)=C(C(O)=O)N2C(=O)[C@@H](NC(=O)CCC[C@@H](N)C(O)=O)[C@@H]12 NNQIJOYQWYKBOW-JWKOBGCHSA-N 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
- C12P35/00—Preparation of compounds having a 5-thia-1-azabicyclo [4.2.0] octane ring system, e.g. cephalosporin
- C12P35/06—Cephalosporin C; Derivatives thereof
Landscapes
- Organic Chemistry (AREA)
- Chemical & Material Sciences (AREA)
- Engineering & Computer Science (AREA)
- Zoology (AREA)
- Life Sciences & Earth Sciences (AREA)
- Wood Science & Technology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Microbiology (AREA)
- General Chemical & Material Sciences (AREA)
- Biotechnology (AREA)
- Health & Medical Sciences (AREA)
- Biochemistry (AREA)
- Bioinformatics & Cheminformatics (AREA)
- General Engineering & Computer Science (AREA)
- General Health & Medical Sciences (AREA)
- Genetics & Genomics (AREA)
- Micro-Organisms Or Cultivation Processes Thereof (AREA)
Abstract
Deacetoxycephalosporin C (I) is produced by culturing a penicillin-N-producing microorganism of the genus Cephalosporium, Emericellopsis, Scopulariopsis, Paecilomyces or Diheterospora in an aq. medium under submersed aerobic conditions. The microorganism is pref. C. Corda NRRL 5445, C. chrysogenum ATCC 14615, Cephalosporium sp. NRRL 5711, 5716 or 5718-5725, Emericellopsis sp. NRRL 5446, 5447, 5713, 5714 or 5717, Scopulariopsis sp. NRRL 5715, P. carneus NRRL 5711 or D. chlamydosporia NRRL 5728. (I) is an inter. for cephalosporin antibiotics.
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US24760872A | 1972-04-26 | 1972-04-26 |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| BE798663A true BE798663A (en) | 1973-10-25 |
Family
ID=22935569
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| BE1004995A BE798663A (en) | 1972-04-26 | 1973-04-25 | Fermentative deacetoxycephalosporin c prodn - with penicillin-n-producing microorganisms |
Country Status (2)
| Country | Link |
|---|---|
| BE (1) | BE798663A (en) |
| ZA (1) | ZA732614B (en) |
-
1973
- 1973-04-16 ZA ZA732614A patent/ZA732614B/en unknown
- 1973-04-25 BE BE1004995A patent/BE798663A/en unknown
Also Published As
| Publication number | Publication date |
|---|---|
| ZA732614B (en) | 1974-11-27 |
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