BE796962A - IMPROVED TECHNETIUM-99M LABELING COMPOSITION AND PREPARATION PROCESS - Google Patents
IMPROVED TECHNETIUM-99M LABELING COMPOSITION AND PREPARATION PROCESSInfo
- Publication number
- BE796962A BE796962A BE1004909A BE1004909A BE796962A BE 796962 A BE796962 A BE 796962A BE 1004909 A BE1004909 A BE 1004909A BE 1004909 A BE1004909 A BE 1004909A BE 796962 A BE796962 A BE 796962A
- Authority
- BE
- Belgium
- Prior art keywords
- preparation process
- labeling composition
- technetium
- improved
- improved technetium
- Prior art date
Links
- GKLVYJBZJHMRIY-OUBTZVSYSA-N Technetium-99 Chemical compound [99Tc] GKLVYJBZJHMRIY-OUBTZVSYSA-N 0.000 title 1
- 238000002372 labelling Methods 0.000 title 1
- 238000002360 preparation method Methods 0.000 title 1
- 229940056501 technetium 99m Drugs 0.000 title 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
- A61K9/16—Agglomerates; Granulates; Microbeadlets ; Microspheres; Pellets; Solid products obtained by spray drying, spray freeze drying, spray congealing,(multiple) emulsion solvent evaporation or extraction
- A61K9/1605—Excipients; Inactive ingredients
- A61K9/1629—Organic macromolecular compounds
- A61K9/1658—Proteins, e.g. albumin, gelatin
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K51/00—Preparations containing radioactive substances for use in therapy or testing in vivo
- A61K51/02—Preparations containing radioactive substances for use in therapy or testing in vivo characterised by the carrier, i.e. characterised by the agent or material covalently linked or complexing the radioactive nucleus
- A61K51/04—Organic compounds
- A61K51/08—Peptides, e.g. proteins, carriers being peptides, polyamino acids, proteins
- A61K51/081—Peptides, e.g. proteins, carriers being peptides, polyamino acids, proteins the protein being an albumin, e.g. human serum albumin [HSA], bovine serum albumin [BSA], ovalbumin
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K51/00—Preparations containing radioactive substances for use in therapy or testing in vivo
- A61K51/12—Preparations containing radioactive substances for use in therapy or testing in vivo characterised by a special physical form, e.g. emulsion, microcapsules, liposomes, characterized by a special physical form, e.g. emulsions, dispersions, microcapsules
- A61K51/1217—Dispersions, suspensions, colloids, emulsions, e.g. perfluorinated emulsion, sols
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K51/00—Preparations containing radioactive substances for use in therapy or testing in vivo
- A61K51/12—Preparations containing radioactive substances for use in therapy or testing in vivo characterised by a special physical form, e.g. emulsion, microcapsules, liposomes, characterized by a special physical form, e.g. emulsions, dispersions, microcapsules
- A61K51/1241—Preparations containing radioactive substances for use in therapy or testing in vivo characterised by a special physical form, e.g. emulsion, microcapsules, liposomes, characterized by a special physical form, e.g. emulsions, dispersions, microcapsules particles, powders, lyophilizates, adsorbates, e.g. polymers or resins for adsorption or ion-exchange resins
- A61K51/1255—Granulates, agglomerates, microspheres
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K2123/00—Preparations for testing in vivo
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Chemical & Material Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- Medicinal Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Epidemiology (AREA)
- Animal Behavior & Ethology (AREA)
- Optics & Photonics (AREA)
- Physics & Mathematics (AREA)
- Dispersion Chemistry (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Molecular Biology (AREA)
- Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
- Investigating Or Analysing Biological Materials (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US236159A US3863004A (en) | 1972-03-20 | 1972-03-20 | Denatured macroprotein with divalent tin for tagging with technetium-99m and method of preparation |
Publications (1)
Publication Number | Publication Date |
---|---|
BE796962A true BE796962A (en) | 1973-09-19 |
Family
ID=22888369
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
BE1004909A BE796962A (en) | 1972-03-20 | 1973-03-19 | IMPROVED TECHNETIUM-99M LABELING COMPOSITION AND PREPARATION PROCESS |
Country Status (10)
Country | Link |
---|---|
US (1) | US3863004A (en) |
JP (1) | JPS5328971B2 (en) |
AU (1) | AU472255B2 (en) |
BE (1) | BE796962A (en) |
DE (1) | DE2314059A1 (en) |
FR (1) | FR2182880B1 (en) |
GB (1) | GB1409176A (en) |
IL (1) | IL41767A (en) |
IT (1) | IT989625B (en) |
NL (1) | NL7303842A (en) |
Families Citing this family (26)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US3968221A (en) * | 1972-05-05 | 1976-07-06 | Medi-Physics, Inc. | 99M-Technetium labeled tin colloid radiopharmaceuticals |
US4024233A (en) * | 1972-06-05 | 1977-05-17 | Medi-Physics, Inc. | 99M-technetium labeled macroaggregated human serum albumin pharmaceutical |
US3987157A (en) * | 1974-08-29 | 1976-10-19 | Union Carbide Corporation | Technetium 99-m labeled radio-diagnostic agents employing stannous tartrate and method of preparation |
US3992513A (en) * | 1975-01-07 | 1976-11-16 | Atomic Energy Of Canada Limited | Labelled phospholipid material colloidially dispersed and sized to localize at preselected organs |
US4057617A (en) * | 1975-05-15 | 1977-11-08 | Abramovici J | Method of labeling proteins with technetium |
GB1535847A (en) * | 1976-03-19 | 1978-12-13 | Radiochemical Centre Ltd | Technetium-99m labelled tin colloid for body scanning |
US4094965A (en) * | 1977-04-01 | 1978-06-13 | New England Nuclear Corporation | Diagnostic agents containing albumin and method for making same |
US4226846A (en) * | 1977-04-01 | 1980-10-07 | New England Nuclear Corporation | Albumin microaggregates for radioactive scanning of reticuloendothelial systems |
US4337240A (en) * | 1978-04-20 | 1982-06-29 | New England Nuclear Corporation | Denatured albumin complexes for radioscintigraphic imaging and evaluation of reticuloendothelial systems |
DE3060377D1 (en) * | 1979-08-29 | 1982-07-01 | Nihon Mediphysics Co Ltd | 2-oxopropionaldehyde bis(thiosemicarbazone)derivatives and their production and use |
JPS5645790U (en) * | 1979-09-17 | 1981-04-24 | ||
US4406876A (en) * | 1980-10-14 | 1983-09-27 | Research Foundation Of The State Univ. Of New York | Sulfur free small-particle production of technetium sulfur colloid |
IT1194135B (en) * | 1981-01-05 | 1988-09-14 | Novo Industri As | COMPOSITIONS OF STABILIZED PLASMINE AND METHOD FOR THEIR PREPARATION |
CH652599A5 (en) * | 1981-08-28 | 1985-11-29 | Solco Basel Ag | Method for producing colloidal physiological degradable, human serum albumin containing products and their use. |
JPS61103841A (en) * | 1984-10-26 | 1986-05-22 | Nippon Mejifuijitsukusu Kk | Stable stannous chloride composition to be fed radioactivity technetium mark |
US5013720A (en) * | 1986-05-06 | 1991-05-07 | Abbott Laboratories | SAP-6-Val proteins and methods |
DE3728599A1 (en) * | 1986-12-10 | 1988-06-23 | Hoechst Ag | METHOD FOR PRODUCING AN ORGAN-SPECIFIC SUBSTANCE MARKED WITH TECHNETIUM-99M |
US5071965A (en) * | 1988-07-19 | 1991-12-10 | Mallinckrodt Medical, Inc. | Novel tc-99m complexes |
US5096696A (en) * | 1990-02-05 | 1992-03-17 | The Research Foundation Of State University Of New York | Binding of radiolabeled albumin fragments to fibrin clots |
US5137709A (en) * | 1991-02-15 | 1992-08-11 | The Dow Chemical Company | Layered mixed metal hydroxides for the stabilization of radioactive colloids |
US5306482A (en) * | 1991-04-09 | 1994-04-26 | Merck Frosst Canada, Inc. | Radiopharmaceutical bacteriostats |
GB9107628D0 (en) * | 1991-04-10 | 1991-05-29 | Moonbrook Limited | Preparation of diagnostic agents |
AU3783893A (en) * | 1992-02-28 | 1993-09-13 | Stanley E. Order | Use of aggregated proteins to prolong retention time of a therapeutic agent adjacent a targeted site such as a tumor |
US6730286B2 (en) | 2001-02-28 | 2004-05-04 | Bracco Diagnostics, Inc. | Manufacturing process to control particle size |
DE10317461A1 (en) * | 2003-04-16 | 2004-10-28 | Boehringer Ingelheim Pharma Gmbh & Co. Kg | Preparing microparticles labeled with technetium, useful as powders for inhalation, e.g. to study deposition of pharmaceuticals, such as anticholinergic agents, involves incubation with solution of technetium salt |
FI20040240A0 (en) * | 2004-02-13 | 2004-02-13 | Nokia Corp | Generation of billing information in a communication system |
Family Cites Families (4)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US3663686A (en) * | 1968-04-24 | 1972-05-16 | Minnesota Mining & Mfg | Biodegradable radioactive particles |
US3663687A (en) * | 1968-06-26 | 1972-05-16 | Minnesota Mining & Mfg | Biodegradable parenteral microspherules |
US3725295A (en) * | 1971-07-20 | 1973-04-03 | Atomic Energy Commission | Technetium labeling |
GB1403384A (en) * | 1971-07-20 | 1975-08-28 | Squibb & Sons Inc | Radiochemically labelled macroaggregates of denatured albumins or globulins |
-
1972
- 1972-03-20 US US236159A patent/US3863004A/en not_active Expired - Lifetime
-
1973
- 1973-03-13 GB GB1188673A patent/GB1409176A/en not_active Expired
- 1973-03-13 IL IL41767A patent/IL41767A/en unknown
- 1973-03-16 AU AU53375/73A patent/AU472255B2/en not_active Expired
- 1973-03-19 BE BE1004909A patent/BE796962A/en unknown
- 1973-03-19 DE DE19732314059 patent/DE2314059A1/en not_active Withdrawn
- 1973-03-19 NL NL7303842A patent/NL7303842A/xx unknown
- 1973-03-20 FR FR7309886A patent/FR2182880B1/fr not_active Expired
- 1973-03-20 JP JP3253773A patent/JPS5328971B2/ja not_active Expired
- 1973-03-20 IT IT48899/73A patent/IT989625B/en active
Also Published As
Publication number | Publication date |
---|---|
AU472255B2 (en) | 1976-05-20 |
US3863004A (en) | 1975-01-28 |
DE2314059A1 (en) | 1973-10-04 |
GB1409176A (en) | 1975-10-08 |
JPS5328971B2 (en) | 1978-08-17 |
JPS4954517A (en) | 1974-05-27 |
FR2182880A1 (en) | 1973-12-14 |
NL7303842A (en) | 1973-09-24 |
IT989625B (en) | 1975-06-10 |
FR2182880B1 (en) | 1976-04-09 |
AU5337573A (en) | 1974-09-19 |
IL41767A0 (en) | 1973-05-31 |
IL41767A (en) | 1976-06-30 |
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