BE745786R - Derives de pyrazinamide et procedes pour les - Google Patents

Derives de pyrazinamide et procedes pour les

Info

Publication number
BE745786R
BE745786R BE745786DA BE745786R BE 745786 R BE745786 R BE 745786R BE 745786D A BE745786D A BE 745786DA BE 745786 R BE745786 R BE 745786R
Authority
BE
Belgium
Prior art keywords
pyrazinamide
derivatives
methods
pyrazinamide derivatives
Prior art date
Application number
Other languages
English (en)
Inventor
E J Cragoe
K L Shepard
Original Assignee
Merck & Co Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Merck & Co Inc filed Critical Merck & Co Inc
Application granted granted Critical
Publication of BE745786R publication Critical patent/BE745786R/fr

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D241/00—Heterocyclic compounds containing 1,4-diazine or hydrogenated 1,4-diazine rings
    • C07D241/02—Heterocyclic compounds containing 1,4-diazine or hydrogenated 1,4-diazine rings not condensed with other rings
    • C07D241/10—Heterocyclic compounds containing 1,4-diazine or hydrogenated 1,4-diazine rings not condensed with other rings having three double bonds between ring members or between ring members and non-ring members
    • C07D241/14—Heterocyclic compounds containing 1,4-diazine or hydrogenated 1,4-diazine rings not condensed with other rings having three double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D241/24—Carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals
    • C07D241/26—Carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals with nitrogen atoms directly attached to ring carbon atoms

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
BE745786D 1969-02-12 1970-02-11 Derives de pyrazinamide et procedes pour les BE745786R (fr)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US79880969A 1969-02-12 1969-02-12

Publications (1)

Publication Number Publication Date
BE745786R true BE745786R (fr) 1970-08-11

Family

ID=25174335

Family Applications (1)

Application Number Title Priority Date Filing Date
BE745786D BE745786R (fr) 1969-02-12 1970-02-11 Derives de pyrazinamide et procedes pour les

Country Status (5)

Country Link
US (1) US3577418A (fr)
BE (1) BE745786R (fr)
FR (1) FR2034542A1 (fr)
MT (1) MTP666B (fr)
NL (1) NL7001744A (fr)

Families Citing this family (20)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB1394816A (en) * 1971-03-19 1975-05-21 Ici Ltd Substituted amino diazinyl compounds and pesticidal compositions thereof
US4145551A (en) * 1978-01-09 1979-03-20 Merck & Co., Inc. Pyrazine-2-carbonyloxyguanidines
FI820266L (fi) * 1981-02-02 1982-08-03 Ici Plc Alkanolaminderivater
US4550111A (en) * 1982-01-29 1985-10-29 Imperial Chemical Industries Plc Alkanolamine derivatives
GB8810934D0 (en) * 1987-05-26 1988-06-15 Ici America Inc Amides
GB8810933D0 (en) * 1987-05-26 1988-06-15 Ici America Inc Heterocyclic compounds
GB8812342D0 (en) * 1988-05-25 1988-06-29 Ici America Inc Bicyclic compounds
GB8812343D0 (en) * 1988-05-25 1988-06-29 Ici America Inc Amino compounds
US6858615B2 (en) 2002-02-19 2005-02-22 Parion Sciences, Inc. Phenyl guanidine sodium channel blockers
US6903105B2 (en) * 2003-02-19 2005-06-07 Parion Sciences, Inc. Sodium channel blockers
US20050090505A1 (en) * 2003-08-18 2005-04-28 Johnson Michael R. Methods of reducing risk of infection from pathogens
US20090253714A1 (en) * 2003-08-20 2009-10-08 Johnson Michael R Methods of reducing risk of infection from pathogens
US7745442B2 (en) * 2003-08-20 2010-06-29 Parion Sciences, Inc. Methods of reducing risk of infection from pathogens
JP2007524682A (ja) * 2004-02-12 2007-08-30 メルク　エンド　カムパニー　インコーポレーテッド 代謝調節型グルタミン酸受容体−５の調節物質としてのビピリジルアミド
EP2231280B1 (fr) 2007-12-10 2016-08-10 Novartis AG Pyrazine carboxamides semblable à l'Amiloride en tant que bloqueurs d'ENaC
AR086745A1 (es) 2011-06-27 2014-01-22 Parion Sciences Inc 3,5-diamino-6-cloro-n-(n-(4-(4-(2-(hexil(2,3,4,5,6-pentahidroxihexil)amino)etoxi)fenil)butil)carbamimidoil)pirazina-2-carboxamida
CN108658876A (zh) 2012-12-17 2018-10-16 帕里昂科学公司 3,5-二氨基-6-氯-n-(n-(4-苯基丁基)甲脒基)吡嗪-2-甲酰胺化合物
CN105073717B (zh) 2012-12-17 2018-05-22 帕里昂科学公司 可用于治疗由黏膜水化不足造成的疾病的氯-吡嗪甲酰胺衍生物
US9102633B2 (en) 2013-12-13 2015-08-11 Parion Sciences, Inc. Arylalkyl- and aryloxyalkyl-substituted epithelial sodium channel blocking compounds
UY36034A (es) 2014-03-18 2015-09-30 Astrazeneca Ab Derivados de 3,5-diamino-6-cloro-pirazina-2-carboxamida y sales farmaceuticamente aceptables de estos

Also Published As

Publication number Publication date
US3577418A (en) 1971-05-04
NL7001744A (fr) 1970-08-14
MTP666B (en) 1970-12-29
FR2034542A1 (fr) 1970-12-11

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