BE492297A - - Google Patents

Info

Publication number

BE492297A

BE492297A BE492297DA BE492297A BE 492297 A BE492297 A BE 492297A BE 492297D A BE492297D A BE 492297DA BE 492297 A BE492297 A BE 492297A

Authority

BE

Belgium

Prior art keywords

pyridyl

carbinol

methanol

tartrate

acid

Prior art date

Links

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• OKKJLVBELUTLKV-UHFFFAOYSA-N Methanol Chemical compound OC OKKJLVBELUTLKV-UHFFFAOYSA-N 0.000 claims description 23
• FEWJPZIEWOKRBE-JCYAYHJZSA-N Dextrotartaric acid Chemical compound OC(=O)[C@H](O)[C@@H](O)C(O)=O FEWJPZIEWOKRBE-JCYAYHJZSA-N 0.000 claims description 7
• 229940095064 tartrate Drugs 0.000 claims description 6
• 239000002253 acid Substances 0.000 claims description 5
• MVQVNTPHUGQQHK-UHFFFAOYSA-N 3-pyridinemethanol Chemical compound OCC1=CC=CN=C1 MVQVNTPHUGQQHK-UHFFFAOYSA-N 0.000 claims description 4
• 238000000034 method Methods 0.000 claims description 3
• 238000002360 preparation method Methods 0.000 claims description 3
• FEWJPZIEWOKRBE-UHFFFAOYSA-N Tartaric acid Natural products [H+].[H+].[O-]C(=O)C(O)C(O)C([O-])=O FEWJPZIEWOKRBE-UHFFFAOYSA-N 0.000 claims description 2
• 238000006243 chemical reaction Methods 0.000 claims description 2
• 150000001875 compounds Chemical class 0.000 claims description 2
• PTMBWNZJOQBTBK-UHFFFAOYSA-N pyridin-4-ylmethanol Chemical compound OCC1=CC=NC=C1 PTMBWNZJOQBTBK-UHFFFAOYSA-N 0.000 claims description 2
• 239000002904 solvent Substances 0.000 claims description 2
• 235000002906 tartaric acid Nutrition 0.000 claims description 2
• 239000011975 tartaric acid Substances 0.000 claims description 2
• 239000013078 crystal Substances 0.000 description 3
• 150000003839 salts Chemical class 0.000 description 2
• XLYOFNOQVPJJNP-UHFFFAOYSA-N water Substances O XLYOFNOQVPJJNP-UHFFFAOYSA-N 0.000 description 2
• 239000013543 active substance Substances 0.000 description 1
• 230000015572 biosynthetic process Effects 0.000 description 1
• 238000009835 boiling Methods 0.000 description 1
• 238000001816 cooling Methods 0.000 description 1
• 239000003814 drug Substances 0.000 description 1
• 238000001914 filtration Methods 0.000 description 1
• 239000007788 liquid Substances 0.000 description 1
• 238000004519 manufacturing process Methods 0.000 description 1
• 239000000203 mixture Substances 0.000 description 1
• 239000007858 starting material Substances 0.000 description 1
• 238000003786 synthesis reaction Methods 0.000 description 1
• 229940124597 therapeutic agent Drugs 0.000 description 1
• 229940124549 vasodilator Drugs 0.000 description 1
• 239000003071 vasodilator agent Substances 0.000 description 1
• 238000010792 warming Methods 0.000 description 1