BE2011C037I2 - - Google Patents

Info

Publication number
BE2011C037I2
BE2011C037I2 BE2011C037C BE2011C037C BE2011C037I2 BE 2011C037 I2 BE2011C037 I2 BE 2011C037I2 BE 2011C037 C BE2011C037 C BE 2011C037C BE 2011C037 C BE2011C037 C BE 2011C037C BE 2011C037 I2 BE2011C037 I2 BE 2011C037I2
Authority
BE
Belgium
Prior art keywords
derivatives
peperidino
mycaminosyltylonolide
pasteurellosis
disubstituted
Prior art date
Application number
BE2011C037C
Other languages
French (fr)
Original Assignee
Zh Biseibutsu Kagaku Kenkyu Kai
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Zh Biseibutsu Kagaku Kenkyu Kai filed Critical Zh Biseibutsu Kagaku Kenkyu Kai
Publication of BE2011C037I2 publication Critical patent/BE2011C037I2/fr

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
    • C07H17/00—Compounds containing heterocyclic radicals directly attached to hetero atoms of saccharide radicals
    • C07H17/04—Heterocyclic radicals containing only oxygen as ring hetero atoms
    • C07H17/08—Hetero rings containing eight or more ring members, e.g. erythromycins
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00—Drugs for disorders of the respiratory system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04—Antibacterial agents

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Veterinary Medicine (AREA)
  • Biochemistry (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • General Chemical & Material Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Public Health (AREA)
  • Molecular Biology (AREA)
  • Genetics & Genomics (AREA)
  • Biotechnology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pulmonology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Communicable Diseases (AREA)
  • Oncology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Dental Preparations (AREA)
  • Medicinal Preparation (AREA)
  • Saccharide Compounds (AREA)
  • External Artificial Organs (AREA)
  • Materials For Medical Uses (AREA)

Abstract

20,23-disubstituted mycaminosyltylonolide derivatives and use of the same in the field of the prophylaxis and treatment of pasteurellosis are disclosed. The di-substituents are peperidino optionally substituted with one or two methyl groups. The derivatives have selective antibacterial activity against Pasteurella.
BE2011C037C 1999-08-30 2011-10-26 BE2011C037I2 (en)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
JP24328699 1999-08-30
EP00955002A EP1216256B1 (en) 1999-08-30 2000-08-24 Macrolide antibiotics and treatment of pasteurellosis
PCT/JP2000/005721 WO2001016148A1 (en) 1999-08-30 2000-08-24 Macrolide antibiotics and treatment of pasteurellosis

Publications (1)

Publication Number Publication Date
BE2011C037I2 true BE2011C037I2 (en) 2019-10-16

Family

ID=17101600

Family Applications (1)

Application Number Title Priority Date Filing Date
BE2011C037C BE2011C037I2 (en) 1999-08-30 2011-10-26

Country Status (13)

Country Link
US (1) US6514946B1 (en)
EP (1) EP1216256B1 (en)
JP (1) JP4573411B2 (en)
AT (1) ATE261450T1 (en)
AU (1) AU763732B2 (en)
BE (1) BE2011C037I2 (en)
CA (1) CA2391834C (en)
DE (2) DE60008895T2 (en)
DK (1) DK1216256T3 (en)
ES (1) ES2213597T3 (en)
FR (1) FR11C0037I2 (en)
PT (1) PT1216256E (en)
WO (1) WO2001016148A1 (en)

Families Citing this family (23)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2006078032A1 (en) * 2005-01-24 2006-07-27 Microbial Chemistry Research Foundation Anti-penicillin resistant pneumococci agent and novel 16-membered ring macrolide derivative
US9148795B2 (en) * 2005-12-22 2015-09-29 Qualcomm Incorporated Methods and apparatus for flexible reporting of control information
KR101456308B1 (en) * 2006-07-28 2014-11-03 인터벳 인터내셔널 비.브이. Macrolide synthesis process
UA98303C2 (en) * 2006-07-28 2012-05-10 Интервет Интернешонал Б.В. Macrolide synthesis process
CN102875622B (en) * 2006-07-28 2016-12-07 英特威国际有限公司 Macrolide synthesis process
EP2019112A1 (en) * 2007-07-26 2009-01-28 Intervet International BV Macrolide solid-state forms
CN102863487B (en) * 2012-10-08 2014-11-05 齐鲁动物保健品有限公司 Process for preparing 20,23-bi-piperidyl-5-O-carbon mould amine glycosyl-tylosin lactone
NO2999707T3 (en) * 2013-05-23 2018-08-25
CN103554203A (en) * 2013-08-17 2014-02-05 齐鲁动物保健品有限公司 Amorphous crystal of tylonolide, and preparation method thereof
CN108864228B (en) * 2014-01-22 2021-02-02 镇江威特药业有限责任公司 Sixteen-membered ring triamine lactone derivative and application thereof
CN103923141B (en) * 2014-04-21 2016-04-27 西南大学 A kind of synthetic method of relying on tilmicosin
CN104478974B (en) * 2014-11-28 2016-08-17 武汉回盛生物科技有限公司 A kind of 20, the synthetic method of 23-dipiperidino-5-O-mycamino syl-tylono lide
CN104447919B (en) * 2014-11-28 2017-03-08 武汉回盛生物科技股份有限公司 A kind of process for purification of 20,23 dipiperidino, 5 O mycaminose Ji Taile lactone bulk drug
CN104497082B (en) * 2015-01-13 2017-12-12 中国兽医药品监察所 A kind of synthetic method of tylonolide
CN104558076A (en) * 2015-02-10 2015-04-29 上海皓元化学科技有限公司 Preparation method of tildipirosin and intermediate compounds of tildipirosin
US10287275B2 (en) * 2015-04-16 2019-05-14 Victor Pharma Co., Ltd. Zhenjiang 16-member triamilide derivatives and uses thereof
CN105440093A (en) * 2015-11-17 2016-03-30 宁夏泰瑞制药股份有限公司 Synthetic method of tildipirosin
CN105919933A (en) * 2016-06-13 2016-09-07 上海同仁药业股份有限公司 Tildipirosin injection and preparation method thereof
CN106420600A (en) * 2016-09-21 2017-02-22 中国水产科学研究院珠江水产研究所 In situ gel for tilmicosin injection and preparation method thereof
CN108264530A (en) * 2016-12-30 2018-07-10 湖北回盛生物科技有限公司 20,23- dihalo -5-O- mycamino syl-tylono lides and its synthetic method and application
CN108264529A (en) * 2016-12-30 2018-07-10 湖北回盛生物科技有限公司 A kind of synthetic method of bis- piperidines -5-O- mycamino syl-tylono lides of 20,23-
ES3032032T3 (en) 2020-12-03 2025-07-15 Intervet Int Bv Tildipirosin for the treatment of foot rot
CN116731096B (en) * 2023-06-10 2025-03-04 中国兽医药品监察所 20-Aldehyde-23-piperidyl-5-O-carbomycaminose-tylosin lactone and its synthesis process and use

Family Cites Families (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4454314A (en) * 1982-08-02 1984-06-12 Pfizer Inc. Antibacterial mycaminosyl tylonolide and related macrolide derivatives
JPS5951299A (en) * 1982-09-17 1984-03-24 Microbial Chem Res Found 23-deoxy-20-dihydro-mycaminosyltylonolide derivative
JPS59225199A (en) * 1983-02-10 1984-12-18 Microbial Chem Res Found 20,23-dideoxy-23-alkyleneimino-20-substituted amino mycaminosylleronolide
ZA841277B (en) * 1983-02-28 1985-09-25 Lilly Co Eli C-20-and c-23-modified macrolide derivatives
IL71032A0 (en) * 1983-02-28 1984-05-31 Lilly Co Eli C-20 and c-23-modified macrolide derivatives
US4629786A (en) 1983-02-28 1986-12-16 Eli Lilly And Company C-20- and C-23 modified macrolide derivatives
JPS59181299A (en) * 1983-03-31 1984-10-15 Microbial Chem Res Found 20,23-dideoxy-20,23-bis-substituted amino-mycaminosylleronolide
JPS59227897A (en) * 1983-06-10 1984-12-21 Microbial Chem Res Found 20,23-dideoxy-23-alkyleneimino-20-substituted-mycaminosylleronolide
US4604380A (en) * 1985-01-18 1986-08-05 Eli Lilly And Company C-23-substituted mycaminosyltylonolide compounds, pharmaceutical compositions and methods of use
TW226373B (en) * 1992-07-15 1994-07-11 Pfizer

Also Published As

Publication number Publication date
DK1216256T3 (en) 2004-06-21
DE60008895D1 (en) 2004-04-15
AU6729400A (en) 2001-03-26
JP4573411B2 (en) 2010-11-04
FR11C0037I1 (en) 2011-10-14
AU763732B2 (en) 2003-07-31
DE60008895T2 (en) 2005-01-20
PT1216256E (en) 2004-07-30
JP2001139592A (en) 2001-05-22
WO2001016148A1 (en) 2001-03-08
CA2391834A1 (en) 2001-03-08
FR11C0037I2 (en) 2012-06-22
US6514946B1 (en) 2003-02-04
ATE261450T1 (en) 2004-03-15
ES2213597T3 (en) 2004-09-01
DE122011100013I1 (en) 2011-09-15
CA2391834C (en) 2008-08-05
EP1216256B1 (en) 2004-03-10
EP1216256A1 (en) 2002-06-26

Similar Documents

Publication Publication Date Title
BE2011C037I2 (en)
AU6339599A (en) Quinoline derivatives and their use as antibacterial agents
ZA981132B (en) Methods, compositions and articles for reducing or preventing the effects of inflammation.
GEP19991538B (en) Derivatives of Erytromycin and Pharmaceutical Composition on their Basis
MXPA02001508A (en) Arylmethylcarbonylaminothiazole derivatives and their use as antitumor agents.
FI954979A7 (en) 10,11-Methanedibenzosuberane derivatives used as chemosensitizers
MXPA03000708A (en) Aminopiperidine quinolines and their azaisosteric analogues with antibacterial activity.
FI951538L (en) Compositions, articles and methods for removing oxygen with improved physical properties
ZA973105B (en) Compounds and methods for the selective treatment of cancer and bacterial infections.
BG64475B1 (en) Ziprasidone salts
FI950623A7 (en) Unsaturated carbohydrate derivatives, polymers derived therefrom and their use
AU4133096A (en) Taxoid derivatives, their preparation and their use as antitumor agents
NZ507350A (en) Semi-synthetic ecteinascidins and use in treatment of tumors
GB9902555D0 (en) Medicament
HUP9904367A3 (en) Benzamidine derivatives and the use thereof as medicaments with ltb4-antagonistic effect
PL332643A1 (en) 1h-pyrido-[3,4-b]-indolo-4-carboxyamidic derivatives, their production and application in medical treatment
PT946175E (en) USE OF A COMBINATION OF H +, K + -ATPASE AND GLUCOCORTICIOD INHIBITORS IN THE TREATMENT OF NASA POLLS
HUT75949A (en) 13-substituted milbemycin derivatives, their use as herbicids and herbicid compositions
AU3825995A (en) Blocking expression of virulence factors in s. aureus
DE69635224D1 (en) 1,3-DIHYDRO-2H-IMIDAZOLE-2-ON DERIVATIVES WITH PDEIV AND CYTOKIN INHIBITING ACTIVITY
DE69108020D1 (en) Polymer composition, and moldings made therefrom.
PT1052991E (en) USING LOPERAMID FOR THE TREATMENT OF MICROBIAL INFECTIONS
AU6091299A (en) Treatment device, treatment bed to be used therein and the use thereof
AU3061199A (en) Skin treatment compositions and the use thereof
EE200200267A (en) Substituted 1,2,3,4,5,6-hexahydro-2,6-methano-3-benzazocines and their use as medicaments