BE1030865B1 - FEED ADDITIVE FOR IMPROVING INTESTINAL HEALTH AND/OR DIGESTIBILITY OF FEED IN LIVESTOCK - Google Patents

FEED ADDITIVE FOR IMPROVING INTESTINAL HEALTH AND/OR DIGESTIBILITY OF FEED IN LIVESTOCK

Info

Publication number
BE1030865B1
BE1030865B1 BE20225716A BE202205716A BE1030865B1 BE 1030865 B1 BE1030865 B1 BE 1030865B1 BE 20225716 A BE20225716 A BE 20225716A BE 202205716 A BE202205716 A BE 202205716A BE 1030865 B1 BE1030865 B1 BE 1030865B1
Authority
BE
Belgium
Prior art keywords
feed
feed additive
digestibility
livestock
enzyme activity
Prior art date
Application number
BE20225716A
Other languages
Dutch (nl)
Other versions
BE1030865A1 (en
Inventor
Dirk Janssens
Ronny Mombaerts
Original Assignee
Nu3Guts Bv
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Nu3Guts Bv filed Critical Nu3Guts Bv
Priority to BE20225716A priority Critical patent/BE1030865B1/en
Priority to NL2035782A priority patent/NL2035782A/en
Priority to BE20235744A priority patent/BE1030811B1/en
Publication of BE1030865A1 publication Critical patent/BE1030865A1/en
Application granted granted Critical
Publication of BE1030865B1 publication Critical patent/BE1030865B1/en

Links

Classifications

    • A—HUMAN NECESSITIES
    • A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
    • A23K—FODDER
    • A23K20/00—Accessory food factors for animal feeding-stuffs
    • A23K20/10—Organic substances
    • A23K20/189—Enzymes
    • A—HUMAN NECESSITIES
    • A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
    • A23K—FODDER
    • A23K10/00—Animal feeding-stuffs
    • A23K10/10—Animal feeding-stuffs obtained by microbiological or biochemical processes
    • A23K10/14—Pretreatment of feeding-stuffs with enzymes
    • A—HUMAN NECESSITIES
    • A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
    • A23K—FODDER
    • A23K10/00—Animal feeding-stuffs
    • A23K10/30—Animal feeding-stuffs from material of plant origin, e.g. roots, seeds or hay; from material of fungal origin, e.g. mushrooms
    • A—HUMAN NECESSITIES
    • A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
    • A23K—FODDER
    • A23K10/00—Animal feeding-stuffs
    • A23K10/30—Animal feeding-stuffs from material of plant origin, e.g. roots, seeds or hay; from material of fungal origin, e.g. mushrooms
    • A23K10/37—Animal feeding-stuffs from material of plant origin, e.g. roots, seeds or hay; from material of fungal origin, e.g. mushrooms from waste material
    • A—HUMAN NECESSITIES
    • A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
    • A23K—FODDER
    • A23K10/00—Animal feeding-stuffs
    • A23K10/30—Animal feeding-stuffs from material of plant origin, e.g. roots, seeds or hay; from material of fungal origin, e.g. mushrooms
    • A23K10/37—Animal feeding-stuffs from material of plant origin, e.g. roots, seeds or hay; from material of fungal origin, e.g. mushrooms from waste material
    • A23K10/38—Animal feeding-stuffs from material of plant origin, e.g. roots, seeds or hay; from material of fungal origin, e.g. mushrooms from waste material from distillers' or brewers' waste
    • A—HUMAN NECESSITIES
    • A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
    • A23K—FODDER
    • A23K20/00—Accessory food factors for animal feeding-stuffs
    • A23K20/10—Organic substances
    • A23K20/174—Vitamins
    • A—HUMAN NECESSITIES
    • A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
    • A23K—FODDER
    • A23K50/00—Feeding-stuffs specially adapted for particular animals
    • A23K50/10—Feeding-stuffs specially adapted for particular animals for ruminants
    • A—HUMAN NECESSITIES
    • A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
    • A23K—FODDER
    • A23K50/00—Feeding-stuffs specially adapted for particular animals
    • A23K50/20—Feeding-stuffs specially adapted for particular animals for horses
    • A—HUMAN NECESSITIES
    • A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
    • A23K—FODDER
    • A23K50/00—Feeding-stuffs specially adapted for particular animals
    • A23K50/30—Feeding-stuffs specially adapted for particular animals for swines
    • A—HUMAN NECESSITIES
    • A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
    • A23K—FODDER
    • A23K50/00—Feeding-stuffs specially adapted for particular animals
    • A23K50/70—Feeding-stuffs specially adapted for particular animals for birds
    • A23K50/75—Feeding-stuffs specially adapted for particular animals for birds for poultry
    • A—HUMAN NECESSITIES
    • A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
    • A23K—FODDER
    • A23K50/00—Feeding-stuffs specially adapted for particular animals
    • A23K50/80—Feeding-stuffs specially adapted for particular animals for aquatic animals, e.g. fish, crustaceans or molluscs
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
    • C12N9/14—Hydrolases (3)
    • C12N9/48—Hydrolases (3) acting on peptide bonds (3.4)
    • C12N9/50—Proteinases, e.g. Endopeptidases (3.4.21-3.4.25)
    • C12N9/52—Proteinases, e.g. Endopeptidases (3.4.21-3.4.25) derived from bacteria or Archaea
    • C12N9/54—Proteinases, e.g. Endopeptidases (3.4.21-3.4.25) derived from bacteria or Archaea bacteria being Bacillus
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
    • C12N9/14—Hydrolases (3)
    • C12N9/48—Hydrolases (3) acting on peptide bonds (3.4)
    • C12N9/50—Proteinases, e.g. Endopeptidases (3.4.21-3.4.25)
    • C12N9/58—Proteinases, e.g. Endopeptidases (3.4.21-3.4.25) derived from fungi
    • C12N9/62—Proteinases, e.g. Endopeptidases (3.4.21-3.4.25) derived from fungi from Aspergillus
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
    • C12N9/14—Hydrolases (3)
    • C12N9/78—Hydrolases (3) acting on carbon to nitrogen bonds other than peptide bonds (3.5)

Landscapes

  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Polymers & Plastics (AREA)
  • Engineering & Computer Science (AREA)
  • Animal Husbandry (AREA)
  • Food Science & Technology (AREA)
  • Zoology (AREA)
  • Birds (AREA)
  • Physiology (AREA)
  • Molecular Biology (AREA)
  • Biotechnology (AREA)
  • Health & Medical Sciences (AREA)
  • Botany (AREA)
  • Mycology (AREA)
  • Microbiology (AREA)
  • Biochemistry (AREA)
  • Marine Sciences & Fisheries (AREA)
  • Insects & Arthropods (AREA)
  • Biomedical Technology (AREA)
  • Fodder In General (AREA)

Abstract

De huidige uitvinding betreft voederadditief voor het verbeteren van de darmgezondheid en/of de verteerbaarheid van voeder in vee, omvattende een serineprotease isoleerbaar uit Bacillus licheniformis met een eerste enzymactiviteit gemeten bij een pH gelegen tussen 7 en 8, en een zuur endoprotease isoleerbaar uit Aspergillus niger met een tweede enzymactiviteit gemeten bij een pH gelegen tussen 2,5 en 3,5, waarin de verhouding tussen de eerste enzymactiviteit en de tweede enzymactiviteit gelegen is tussen 0,8/1 en 1/0,8. De uitvinding betreft eveneens een werkwijze voor het bereiden van een voornoemd voederadditief, alsook een voedersamenstelling omvattende voornoemd voederadditief en een gebruik van voornoemd voederadditief.The present invention concerns a feed additive for improving intestinal health and/or the digestibility of feed in livestock, comprising a serine protease isolable from Bacillus licheniformis with a first enzyme activity measured at a pH between 7 and 8, and an acid endoprotease isolable from Aspergillus niger with a second enzyme activity measured at a pH between 2.5 and 3.5, wherein the ratio between the first enzyme activity and the second enzyme activity is between 0.8/1 and 1/0.8. The invention also concerns a method for preparing said feed additive, as well as a feed composition comprising said feed additive and a use of said feed additive.

BE20225716A 2022-09-12 2022-09-12 FEED ADDITIVE FOR IMPROVING INTESTINAL HEALTH AND/OR DIGESTIBILITY OF FEED IN LIVESTOCK BE1030865B1 (en)

Priority Applications (3)

Application Number Priority Date Filing Date Title
BE20225716A BE1030865B1 (en) 2022-09-12 2022-09-12 FEED ADDITIVE FOR IMPROVING INTESTINAL HEALTH AND/OR DIGESTIBILITY OF FEED IN LIVESTOCK
NL2035782A NL2035782A (en) 2022-09-12 2023-09-12 FEED ADDITIVE FOR IMPROVING INTESTINAL HEALTH AND/OR DIGESTIBILITY OF FEED IN LIVESTOCK
BE20235744A BE1030811B1 (en) 2022-09-12 2023-09-12 Feed additive to improve intestinal health and/or feed digestibility in livestock

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
BE20225716A BE1030865B1 (en) 2022-09-12 2022-09-12 FEED ADDITIVE FOR IMPROVING INTESTINAL HEALTH AND/OR DIGESTIBILITY OF FEED IN LIVESTOCK

Publications (2)

Publication Number Publication Date
BE1030865A1 BE1030865A1 (en) 2024-04-04
BE1030865B1 true BE1030865B1 (en) 2024-04-09

Family

ID=83362614

Family Applications (2)

Application Number Title Priority Date Filing Date
BE20225716A BE1030865B1 (en) 2022-09-12 2022-09-12 FEED ADDITIVE FOR IMPROVING INTESTINAL HEALTH AND/OR DIGESTIBILITY OF FEED IN LIVESTOCK
BE20235744A BE1030811B1 (en) 2022-09-12 2023-09-12 Feed additive to improve intestinal health and/or feed digestibility in livestock

Family Applications After (1)

Application Number Title Priority Date Filing Date
BE20235744A BE1030811B1 (en) 2022-09-12 2023-09-12 Feed additive to improve intestinal health and/or feed digestibility in livestock

Country Status (2)

Country Link
BE (2) BE1030865B1 (en)
NL (1) NL2035782A (en)

Citations (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US20080031999A1 (en) * 2006-08-07 2008-02-07 Novozymes A/S Enzyme Granules for Animal Feed
CN105779423A (en) * 2015-11-17 2016-07-20 济南诺能生物工程有限公司 Compound protease as well as production method and applications thereof
CN106497902A (en) * 2016-10-14 2017-03-15 济南诺能生物工程有限公司 A kind of compound protein enzyme preparation for improving broiler protein digestibility and its broiler fodder
CN108450667A (en) * 2016-12-09 2018-08-28 上海欧耐施生物技术有限公司 A kind of compound protease effectively improving feed protein utilization rate and its application
CN110973371A (en) * 2019-12-31 2020-04-10 河南科技大学 Livestock and poultry egg white enzyme feed additive and application thereof
CN111000052A (en) * 2019-12-31 2020-04-14 河南科技大学 Piglet enzyme bacterium feed additive and application thereof
US20220088151A1 (en) * 2019-02-07 2022-03-24 Bright Lifecare Pvt. Ltd Proteolytic enzyme composition

Family Cites Families (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DK91192D0 (en) 1992-07-10 1992-07-10 Novo Nordisk As PROTEIN
FI109759B (en) * 1996-12-23 2002-10-15 Suomen Rehu Oy Use of a food additive
US7319087B2 (en) 2001-05-04 2008-01-15 Novozymes A/S Antimicrobial polypeptide from Aspergillus niger
NZ532962A (en) 2001-11-20 2006-11-30 Novozymes As Antimicrobial polypeptides from pseudoplectania nigrella
JP2005513042A (en) 2001-12-03 2005-05-12 ノボザイムス アクティーゼルスカブ Statin-like compounds
WO2004034776A2 (en) 2002-08-09 2004-04-29 North Carolina State University Methods and compositions for improving growth of meat-type poultry
CA2633066C (en) * 2005-12-15 2015-01-20 Chemgen Corporation Enzymes for reduced immunological stress

Patent Citations (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US20080031999A1 (en) * 2006-08-07 2008-02-07 Novozymes A/S Enzyme Granules for Animal Feed
CN105779423A (en) * 2015-11-17 2016-07-20 济南诺能生物工程有限公司 Compound protease as well as production method and applications thereof
CN106497902A (en) * 2016-10-14 2017-03-15 济南诺能生物工程有限公司 A kind of compound protein enzyme preparation for improving broiler protein digestibility and its broiler fodder
CN108450667A (en) * 2016-12-09 2018-08-28 上海欧耐施生物技术有限公司 A kind of compound protease effectively improving feed protein utilization rate and its application
US20220088151A1 (en) * 2019-02-07 2022-03-24 Bright Lifecare Pvt. Ltd Proteolytic enzyme composition
CN110973371A (en) * 2019-12-31 2020-04-10 河南科技大学 Livestock and poultry egg white enzyme feed additive and application thereof
CN111000052A (en) * 2019-12-31 2020-04-14 河南科技大学 Piglet enzyme bacterium feed additive and application thereof

Non-Patent Citations (2)

* Cited by examiner, † Cited by third party
Title
ARYA PRASHANT S ET AL: "Valorization of agro-food wastes: Ease of concomitant-enzymes production with application in food and biofuel industries", BIORESOURCE TECHNOLOGY, ELSEVIER, AMSTERDAM, NL, vol. 361, 5 August 2022 (2022-08-05), XP087163495, ISSN: 0960-8524, [retrieved on 20220805], DOI: 10.1016/J.BIORTECH.2022.127738 *
SILVA RONIVALDO RODRIGUES DA ED - LEI YU: "Bacterial and Fungal Proteolytic Enzymes: Production, Catalysis and Potential Applications", APPLIED BIOCHEMISTRY AND BIOTECHNOLOGY, HUMANA PRESS INC, NEW YORK, vol. 183, no. 1, 3 February 2017 (2017-02-03), pages 1 - 19, XP036313939, ISSN: 0273-2289, [retrieved on 20170203], DOI: 10.1007/S12010-017-2427-2 *

Also Published As

Publication number Publication date
BE1030865A1 (en) 2024-04-04
NL2035782A (en) 2024-03-14
BE1030811A1 (en) 2024-03-19
BE1030811B1 (en) 2024-09-24

Similar Documents

Publication Publication Date Title
EP3160260B1 (en) A method for improving the nutritional value of animal feed
MX2019003250A (en) Use of low ph active alpha-1,4/1,6-glycoside hydrolases as a feed additive for ruminants to enhance starch digestion.
ATE244302T1 (en) PHYTATE HYDROLYSIS AND ENZYMATIC COMPOSITION FOR THE HYDROLYSIS OF PHYTATE
MXPA05001727A (en) Compositions and process for delivering an additive.
EA201171291A1 (en) FEED ADDITIVE
WO2019040935A8 (en) Evolution of bont peptidases
RU2014119583A (en) STRAIN OF BACILLUS AND ITS COMPOSITION
TWI350731B (en) Process for the granulation of an animal feedstuff additive
MXPA05009315A (en) Use of proteolytic enzymes to increase feed utilization in ruminant diets.
MX2021010264A (en) Stable protein formulations.
FI961622A0 (en) Arabinoxylan - degrading enzymes
DK1237569T3 (en) animal feed additive
RU2015105743A (en) METHOD FOR DESTRUCTING KERATIN AND APPLICATION OF THE PRODUCED HYDROLYSATE
Cole et al. Purification and partial characterisation of a novel trypsin-like cysteine protease from Metarhizium anisopliae
RU2008101939A (en) SYNERGIC EFFECT OF PHYTASIS COMBINATION IN RESPECT OF PHYTINIC ACID HYDROLYSIS
RS50592B (en) Feed or feed additive containing an alkaloid
UA87297C2 (en) Antiparasitic feed premix for animals and method for making thereof
TW200616553A (en) Stabilized pancreas product
BE1030865B1 (en) FEED ADDITIVE FOR IMPROVING INTESTINAL HEALTH AND/OR DIGESTIBILITY OF FEED IN LIVESTOCK
DE69802938D1 (en) USE OF AN ENZYME TO PREPARE BACTERIAL INFECTION
BRPI0503756A (en) soybean processing method by the use of specific enzyme, processed soybean powder and processed soybean liquid
Das et al. Effect of nutritional supplementation of solid state fermentation medium on biosynthesis of phytase from Aspergillus niger NCIM 612
MXPA04002041A (en) Method for the production of oily suspensions of water-soluble enzymes.
MX2023002477A (en) Feed composition supplemented with a protease combination comprising neutral metalloprotease and serine alkaline protease at a given ratio.
MX2024007868A (en) A method for reducing ammonia emission of animals.

Legal Events

Date Code Title Description
FG Patent granted

Effective date: 20240409