BE1026481B1 - HERBICIDE COMPOSITION - Google Patents

Abstract

Compositions comprising diflufenican and prosulfocarb are described herein. Such compositions exhibit stability over a long period of time and are therefore more flexible to be stored and handled.

Description

HERBICIDE COMPOSITION

TECHNICAL FIELD OF THE INVENTION

The present invention relates to a stable composition comprising diflufenican and prosulfocarb and the use of such a composition for combating undesired vegetation in agricultural crops.

BACKGROUND OF THE INVENTION

Difluphenican (DFF or N- (2,4-difluorophenyl) -2- [3- (trifluoromethyl) phenoxy] -3-pyridinecarboxamide) belongs to the group of pyridinecarboxamide herbicides and acts as an inhibitor of carotenoid biosynthesis.

Figure 1 Diflufenican

Prosulfocarb (S- (phenylmethyl) dipropyl carbamothioate), on the other hand, belongs to the herbicides of the thiocarbamate class and acts as an inhibitor of lipid synthesis.

O

CH ₃

Figure 1 Prosulfocarb

EP 2 198 712 describes a herbicide composition comprising diflufenican and prosulfocarb, wherein the mixing ratios of diflufenican to prosulfocarb are from 50: 1 to 1:50.

SUMMARY OF THE INVENTION

One of the major problems of compositions comprising diflufenican and prosulfocarb mixture is that such compositions are susceptible to degradation of active ingredients and therefore not suitable for long-term storage.

BE2018 / 5521

- 2 It has surprisingly been found that in compositions of the present invention degradation of active ingredients and consequently the formation of their degradation products is avoided or delayed, therefore the stability of the compositions is maintained for a longer period and a more flexible storage and handling is provided.

According to the present invention, stable compositions comprise:

diflufenican prosulfocarb one or more emulsifiers, and an organic solvent.

In one aspect of the present invention, prosulfocarb is present in an amount of 500-800 g / L of the composition.

In another aspect, diflufenican is present in an amount of 10-50 g / L of the composition.

In a further aspect, at least one organic solvent is present in an amount of 10-50% w / V.

Compositions of the present invention comprise one or more emulsifiers in an amount of 5-30% w / V.

Compositions of the present invention include one or more emulsifiers selected from anionic emulsifiers, non-ionic emulsifiers, and mixtures thereof.

In a further aspect, compositions of the present invention are used as a herbicide for combating undesired vegetation in agricultural crops, wherein the crops are selected from potatoes, rice, maize and grains such as barley, wheat, rye, oats and triticale.

DETAILED DESCRIPTION OF THE INVENTION

Stable compositions comprising diflufenican and prosulfocarb are mentioned herein.

The formulations described exhibit acceptable stability with regard to maintaining diflufenican and prosulfocarb efficacy and potency and

BE2018 / 5521

-3 preventing unacceptable degradation of active substances into undesirable related substances.

Term stable as used herein refers to compositions comprising less than 5% diflufenican degradation products and less than 5% prosulfocarb degradation products, determined by HPLC analysis, under typical storage conditions, such as storage at a temperature of 15 ° C for a period of up to 24 months.

Analysis of the compositions of the present invention can be performed using other techniques known in the art.

Example 1. Stability of diflufenican and prosulfocarb composition

Composition comprising diflufenican in an amount of about 14 g / L and prosulfocarb in an amount of about 680 g / L was produced.

The active substances diflufenican and prosulfocarb were mixed together in a suitable solvent and emulsifiers were added to the mixture.

Decomposition of active ingredients into degradation products was calculated with the following equation:

^ active ingredient / Ü = ^COnCentrati ^ active ingredient ~ ^COnCmtration Active ingredient

Percentage of the degradation product was calculated:

^ active ingredient) / ï} 100

Λ Γοζ, Ι = degradation product γ _{r Ί} ^{COnCentration} activeinient \ 9 / ^l i

Time point - Tn Save temperature Cancel Δ diflufenican % Abort Δ prosulfocarb% Initial - T0 pre-storage - - 6 months - T6 15 ° C <5% <5% 12 months - T12 15 ° C <5% <5% 24 months - T24 15 ° C <5% <5%

BE2018 / 5521

Claims (8)

CONCLUSIONS A composition comprising a) diflufenican b) prosulfocarb c) one or more emulsifiers, and d) at least one organic solvent. The composition of claim 1, wherein prosulfocarb is present in an amount of 500-800 g / L of the composition. The composition of claims 1 and 2, wherein diflufenican is present in an amount of 10-50 g / L of the composition. A composition according to any one of the preceding claims, wherein organic solvent is present in an amount of 10-50% w / V. A composition according to any one of the preceding claims, wherein one or more emulsifiers are present in an amount of 5-30% w / V. The composition of claim 5, wherein one or more emulsifiers are selected from anionic emulsifiers, non-ionic emulsifiers, and mixtures thereof. Use of the composition according to any one of the preceding claims for combating undesired vegetation in crops, wherein the crops are grains, potatoes, corn and rice. Use according to claim 7, wherein cereals are selected from barley, wheat, rye, oats and triticale.