AU8923291A - L-2'-desoxyuridines and pharmaceutical compositions containing them - Google Patents

L-2'-desoxyuridines and pharmaceutical compositions containing them

Info

Publication number
AU8923291A
AU8923291A AU89232/91A AU8923291A AU8923291A AU 8923291 A AU8923291 A AU 8923291A AU 89232/91 A AU89232/91 A AU 89232/91A AU 8923291 A AU8923291 A AU 8923291A AU 8923291 A AU8923291 A AU 8923291A
Authority
AU
Australia
Prior art keywords
desoxyuridines
pharmaceutical compositions
compositions containing
pharmaceutical
compositions
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Abandoned
Application number
AU89232/91A
Inventor
Federico Arcamone
Giovanni Ciarrocchi
Francesco Paolo Colonna
Federico Focher
Anna Maria Garbesi
Stefano Iotti
Silvio Spadari
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Consiglio Nazionale delle Richerche CNR
Menarini Ricerche SpA
Original Assignee
Consiglio Nazionale delle Richerche CNR
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Consiglio Nazionale delle Richerche CNR filed Critical Consiglio Nazionale delle Richerche CNR
Publication of AU8923291A publication Critical patent/AU8923291A/en
Abandoned legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
    • C07H19/00—Compounds containing a hetero ring sharing one ring hetero atom with a saccharide radical; Nucleosides; Mononucleotides; Anhydro-derivatives thereof
    • C07H19/02—Compounds containing a hetero ring sharing one ring hetero atom with a saccharide radical; Nucleosides; Mononucleotides; Anhydro-derivatives thereof sharing nitrogen
    • C07H19/04—Heterocyclic radicals containing only nitrogen atoms as ring hetero atom
    • C07H19/06—Pyrimidine radicals

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Biochemistry (AREA)
  • Biotechnology (AREA)
  • General Health & Medical Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Molecular Biology (AREA)
  • Saccharide Compounds (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
AU89232/91A 1990-11-13 1991-11-09 L-2'-desoxyuridines and pharmaceutical compositions containing them Abandoned AU8923291A (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
IT22032/90 1990-11-13
IT02203290A IT1246983B (en) 1990-11-13 1990-11-13 L-2'-DESOXYURIDINE AND PHARMACEUTICAL COMPOSITIONS THAT CONTAIN IT.

Publications (1)

Publication Number Publication Date
AU8923291A true AU8923291A (en) 1992-06-11

Family

ID=11190463

Family Applications (1)

Application Number Title Priority Date Filing Date
AU89232/91A Abandoned AU8923291A (en) 1990-11-13 1991-11-09 L-2'-desoxyuridines and pharmaceutical compositions containing them

Country Status (3)

Country Link
AU (1) AU8923291A (en)
IT (1) IT1246983B (en)
WO (1) WO1992008727A1 (en)

Families Citing this family (33)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5204466A (en) * 1990-02-01 1993-04-20 Emory University Method and compositions for the synthesis of bch-189 and related compounds
US6069252A (en) 1990-02-01 2000-05-30 Emory University Method of resolution and antiviral activity of 1,3-oxathiolane nucleoside enantiomers
US5914331A (en) * 1990-02-01 1999-06-22 Emory University Antiviral activity and resolution of 2-hydroxymethyl-5-(5-fluorocytosin-1-yl)-1,3-oxathiolane
US5276151A (en) * 1990-02-01 1994-01-04 Emory University Method of synthesis of 1,3-dioxolane nucleosides
GB9218810D0 (en) * 1992-09-04 1992-10-21 Univ Birmingham Antiviral pyrimidine nucleosides
US20020120130A1 (en) 1993-09-10 2002-08-29 Gilles Gosselin 2' or 3' -deoxy and 2', 3' -dideoxy-beta-L-pentofuranonucleo-side compounds, method of preparation and application in therapy, especially as anti- viral agents
FR2709754B1 (en) * 1993-09-10 1995-12-01 Centre Nat Rech Scient Compounds 2 'or 3'-deoxy- and 2', 3'-dideoxy-beta-L-pentofuranonucleosides, preparation process and therapeutic application, in particular anti-viral.
US5587362A (en) * 1994-01-28 1996-12-24 Univ. Of Ga Research Foundation L-nucleosides
US5559101A (en) * 1994-10-24 1996-09-24 Genencor International, Inc. L-ribofuranosyl nucleosides
ATE284894T1 (en) * 1994-10-24 2005-01-15 Genencor Int L-PYRANOSYL NUCLEOSIDES
US6391859B1 (en) 1995-01-27 2002-05-21 Emory University [5-Carboxamido or 5-fluoro]-[2′,3′-unsaturated or 3′-modified]-pyrimidine nucleosides
US5703058A (en) * 1995-01-27 1997-12-30 Emory University Compositions containing 5-fluoro-2',3'-didehydro-2',3'-dideoxycytidine or a mono-, di-, or triphosphate thereof and a second antiviral agent
US5808040A (en) * 1995-01-30 1998-09-15 Yale University L-nucleosides incorporated into polymeric structure for stabilization of oligonucleotides
US5753789A (en) * 1996-07-26 1998-05-19 Yale University Oligonucleotides containing L-nucleosides
IL129126A0 (en) * 1996-10-16 2000-02-17 Icn Pharmaceuticals Monocyclic l-nucleosides analogs and uses thereof
EP1302474A1 (en) * 1996-10-16 2003-04-16 Ribapharm, Inc. Monocyclic L-nucleosides, analogs and uses thereof
BR9908270A (en) 1998-02-25 2004-06-29 Univ Emory 2-Fluoro-nucleosides, pharmaceutical compositions and their uses
ES2579903T3 (en) 1998-08-10 2016-08-17 Centre National De La Recherche Scientifique (Cnrs) Beta-L-2'-deoxy-nucleosides for the treatment of hepatitis B
AU2007216721B2 (en) * 1998-08-10 2011-05-19 Centre National De La Recherche Scientifique Beta-L-2'-Deoxy Nucleosides for the Treatment of Hepatitis B
EP1431304B1 (en) * 1998-08-10 2014-12-03 Novartis AG Beta - L-2'-Deoxy-Nucleosides for the treatment of Hepatitis B
US6444652B1 (en) 1998-08-10 2002-09-03 Novirio Pharmaceuticals Limited β-L-2'-deoxy-nucleosides for the treatment of hepatitis B
CN101120947B (en) * 1998-08-10 2010-11-24 艾丹尼克斯(开曼)有限公司 Beta-l-2'-deoxy-nucleosides for the treatment of hepatitis b
AU2011211428B2 (en) * 1998-08-10 2013-02-07 Centre National De La Recherche Scientifique Beta-L-2'-Deoxy Nucleosides for the treatment of Hepatitis B
EP1600452A3 (en) * 1999-11-12 2008-09-10 Pharmasset, Inc. Synthesis of 2'-deoxy-L-nucleosides
TR200601782T2 (en) * 1999-11-12 2006-09-21 Pharmasset Ltd. Synthesis of 2'-Deoxy-L-Nucleosides.
US6787526B1 (en) 2000-05-26 2004-09-07 Idenix Pharmaceuticals, Inc. Methods of treating hepatitis delta virus infection with β-L-2′-deoxy-nucleosides
US6875751B2 (en) 2000-06-15 2005-04-05 Idenix Pharmaceuticals, Inc. 3′-prodrugs of 2′-deoxy-β-L-nucleosides
MY141594A (en) * 2000-06-15 2010-05-14 Novirio Pharmaceuticals Ltd 3'-PRODRUGS OF 2'-DEOXY-ß-L-NUCLEOSIDES
CN1646141B (en) 2000-10-18 2014-06-25 吉利德制药有限责任公司 Modified nucleosides for treatment of viral infections and abnormal cellular proliferation
EP1478322A4 (en) 2001-06-22 2007-08-08 Pharmasset Ltd Beta-2'-OR 3'-HALONUCLEOSIDES
TWI244393B (en) 2002-08-06 2005-12-01 Idenix Pharmaceuticals Inc Crystalline and amorphous forms of beta-L-2'-deoxythymidine
PT1572095E (en) 2002-09-13 2015-10-13 Novartis Ag Beta-l-2'-deoxynucleosides for use in the treatment of resistant hbv strains
US8895531B2 (en) 2006-03-23 2014-11-25 Rfs Pharma Llc 2′-fluoronucleoside phosphonates as antiviral agents

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DK167377B1 (en) * 1985-09-17 1993-10-25 Wellcome Found 3'-AZIDOPYRIMIDINE NUCLEOSIDES OR PHARMACEUTICAL ACCEPTABLE SALTS OR ESTERS THEREOF USED FOR TREATMENT OR PROPHYLAXY FOR A HUMAN RETROVIRUS INFECTION
DD279407A1 (en) * 1986-07-24 1990-06-06 Akad Wissenschaften Ddr METHOD FOR PRODUCING AN AGENT AGAINST AIDS
FR2640267B2 (en) * 1988-01-19 1992-02-14 Univ Paris Curie PROCESS FOR THE SYNTHESIS OF AZIDO-3 (PRIME) -DESOXY-3 (PRIME) -THYMIDINE AND THE LIKE
FR2627492B1 (en) * 1988-02-24 1990-08-10 Irceba NOVEL AMINO-5 (PRIME) -DIDEOXY-2 (PRIME) -5 (PRIME) -URIDINE DERIVATIVES, PROCESS FOR THEIR PREPARATION AND PHARMACEUTICAL COMPOSITIONS CONTAINING THESE COMPOUNDS
SE8802687D0 (en) * 1988-07-20 1988-07-20 Astra Ab NUCLEOSIDE DERIVATIVES

Also Published As

Publication number Publication date
IT9022032A0 (en) 1990-11-13
IT9022032A1 (en) 1992-05-13
IT1246983B (en) 1994-12-12
WO1992008727A1 (en) 1992-05-29

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