AU8268987A - Chroman derivatives - Google Patents

Chroman derivatives

Info

Publication number
AU8268987A
AU8268987A AU82689/87A AU8268987A AU8268987A AU 8268987 A AU8268987 A AU 8268987A AU 82689/87 A AU82689/87 A AU 82689/87A AU 8268987 A AU8268987 A AU 8268987A AU 8268987 A AU8268987 A AU 8268987A
Authority
AU
Australia
Prior art keywords
chroman derivatives
chroman
derivatives
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Granted
Application number
AU82689/87A
Other versions
AU604809B2 (en
Inventor
Manfred Dr. Baumgarth
Rolf Dr. Bergmann
Jacques Dr. De Peyer
Rolf Dr. Gericke
Gunter Prof. Dr. Hausler
Inge Dr. Lues
Hanns Dr. Wurziger
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Merck Patent GmbH
Original Assignee
Merck Patent GmbH
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=25850767&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=AU8268987(A) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Merck Patent GmbH filed Critical Merck Patent GmbH
Publication of AU8268987A publication Critical patent/AU8268987A/en
Application granted granted Critical
Publication of AU604809B2 publication Critical patent/AU604809B2/en
Anticipated expiration legal-status Critical
Ceased legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D405/00—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom
    • C07D405/02—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings
    • C07D405/04—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings directly linked by a ring-member-to-ring-member bond
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P21/00—Drugs for disorders of the muscular or neuromuscular system
    • A61P21/02—Muscle relaxants, e.g. for tetanus or cramps
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/12—Antihypertensives
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D311/00—Heterocyclic compounds containing six-membered rings having one oxygen atom as the only hetero atom, condensed with other rings
    • C07D311/02—Heterocyclic compounds containing six-membered rings having one oxygen atom as the only hetero atom, condensed with other rings ortho- or peri-condensed with carbocyclic rings or ring systems
    • C07D311/04—Benzo[b]pyrans, not hydrogenated in the carbocyclic ring
    • C07D311/22—Benzo[b]pyrans, not hydrogenated in the carbocyclic ring with oxygen or sulfur atoms directly attached in position 4
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D405/00—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom
    • C07D405/02—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings
    • C07D405/10—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings linked by a carbon chain containing aromatic rings
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D405/00—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom
    • C07D405/02—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings
    • C07D405/12—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings linked by a chain containing hetero atoms as chain links
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D405/00—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom
    • C07D405/14—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing three or more hetero rings
AU82689/87A 1986-12-23 1987-12-16 Chroman derivatives Ceased AU604809B2 (en)

Applications Claiming Priority (4)

Application Number Priority Date Filing Date Title
DE3644094 1986-12-23
DE3644094 1986-12-23
DE3726261 1987-08-07
DE19873726261 DE3726261A1 (en) 1986-12-23 1987-08-07 CHROME DERIVATIVES

Publications (2)

Publication Number Publication Date
AU8268987A true AU8268987A (en) 1988-06-23
AU604809B2 AU604809B2 (en) 1991-01-03

Family

ID=25850767

Family Applications (1)

Application Number Title Priority Date Filing Date
AU82689/87A Ceased AU604809B2 (en) 1986-12-23 1987-12-16 Chroman derivatives

Country Status (7)

Country Link
EP (1) EP0273262A3 (en)
JP (1) JP2523343B2 (en)
KR (1) KR960004828B1 (en)
AU (1) AU604809B2 (en)
CA (1) CA1340960C (en)
DE (1) DE3726261A1 (en)
HU (1) HU207728B (en)

Cited By (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
AU615275B2 (en) * 1988-03-31 1991-09-26 Hoechst Aktiengesellschaft Unsaturated N-benzopyranyllactams
US5071991A (en) * 1988-12-26 1991-12-10 Sanofi Method of preparing chroman derivatives, and synthesis intermediates
AU618007B2 (en) * 1987-06-23 1991-12-12 Sanofi 2,2-dimethylchroman-3-ol derivatives, process for their preparation and pharmaceutical compositions in which they are present
AU619766B2 (en) * 1987-10-12 1992-02-06 Sanofi 2,2-dimethylchromene derivatives, process for their preparation and pharmaceutical compositions in which they are present

Families Citing this family (35)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE3820506A1 (en) * 1988-06-16 1989-12-21 Merck Patent Gmbh N-Heterocyclically substituted chroman derivatives and their use as medicaments
US5387587A (en) * 1986-12-23 1995-02-07 Merck Patent Gesellschaft Mit Beschrankter Haftung Chroman derivatives
DE3835011A1 (en) * 1988-10-14 1990-04-19 Merck Patent Gmbh CHROME DERIVATIVES
EP0277611B1 (en) * 1987-02-04 1993-06-16 Hoechst Aktiengesellschaft Alkyl-substituted n-benzopyranyl lactames, process for their preparation, their use and pharmaceutical preparations on the basis of these compounds
US5284838A (en) * 1987-06-23 1994-02-08 Elf Sanofi Use of 2,2-dimethylchroman-3-ol derivatives in the treatment of asthma
FI90343C (en) * 1987-06-23 1994-01-25 Merck Patent Gmbh Process for the preparation of antihypertensive and antiarrhythmic trans-2,2-dimethylchroman-3-parent derivatives
DE3732146A1 (en) * 1987-09-24 1989-04-06 Merck Patent Gmbh AZACHROMANDERIVATIVES
GB8800199D0 (en) * 1988-01-06 1988-02-10 Beecham Group Plc Pharmaceutical preparation
US5021432A (en) * 1988-04-26 1991-06-04 Yoshitomi Pharmaceutical Industries, Ltd. Benzopyran compound and its pharmaceutical use
AU628331B2 (en) * 1988-05-06 1992-09-17 Merck Patent Gesellschaft Mit Beschrankter Haftung Chroman derivatives
US5254557A (en) * 1988-05-09 1993-10-19 Beecham Group P.L.C. Compound and treatment
JPH03500542A (en) * 1988-05-09 1991-02-07 ビーチャム　グループ　ピーエルシー Novel compounds and treatments
EP0346724A1 (en) * 1988-06-16 1989-12-20 MERCK PATENT GmbH Chroman derivates
DE3823533A1 (en) * 1988-07-12 1990-02-08 Beiersdorf Ag SUBSTITUTED 4-HETEROCYCLYL-2H-BENZO (B) PYRANEES, METHOD AND 4-HYDROXY-3-BROM, 3,4-OXIRANYL-3,4-DEHYDRO-2H-BENZO (B) PYRANES AS INTERMEDIATE PRODUCTS FOR THEIR MANUFACTURE, AND THE INVENTION PHARMACEUTICAL PRECAUTIONS CONTAINING THEM
DE3827532A1 (en) * 1988-08-13 1990-03-01 Hoechst Ag 6-AROYL-SUBSTITUTED 3,4-DIHYDRO-2H-BENZOPYRANES, METHOD FOR THE PRODUCTION THEREOF, THEIR USE AND PHARMACEUTICAL PREPARATIONS BASED ON THESE COMPOUNDS
DE3837809A1 (en) * 1988-11-08 1990-05-10 Merck Patent Gmbh tetralin
FR2639227A1 (en) * 1988-11-23 1990-05-25 Sanofi Sa USE OF CHROMANE DERIVATIVES FOR THE TREATMENT OF DEPRESSIVE STATES
US5072006A (en) * 1988-12-09 1991-12-10 Recherche Syntex France S.A. Novel benzopyranylpyrrolinone derivatives
EP0376524B1 (en) * 1988-12-13 1995-03-29 Beecham Group Plc Benzopyran and related compounds
DE3904496A1 (en) * 1989-02-15 1990-08-16 Merck Patent Gmbh METHOD FOR ENANTIOMER SEPARATION OF A BENZOPYRANE DERIVATIVE
US5162553A (en) * 1989-03-03 1992-11-10 Yoshitomi Pharmaceutical Industries, Ltd. Processes for preparing optically active 3,4-dihydro-3,4-epoxy-2H-1-benzopyran compounds and intermediates therefor
US5066816A (en) * 1989-03-03 1991-11-19 Yoshitomi Pharmaceutical Industries, Ltd. Processes for preparing optically active 3,4-dihydro-3,4-epoxy-2h-1-benzopyran compounds and intermediates therefor
FR2645021A1 (en) * 1989-03-30 1990-10-05 Sanofi Sa USE OF A POTASSIC AGONIST IN THE TREATMENT OF GLAUCOMA
DE3915236A1 (en) * 1989-05-10 1990-11-15 Merck Patent Gmbh PHARMACEUTICAL PREPARATION
DE3918041A1 (en) * 1989-06-02 1990-12-06 Merck Patent Gmbh CHROME DERIVATIVES
DE3922392A1 (en) 1989-07-07 1991-01-17 Merck Patent Gmbh CHROME DERIVATIVES
DE3923839A1 (en) * 1989-07-19 1991-01-31 Beiersdorf Ag New benzopyran derivs. (I) as vasodilators and spasmolytic agents - for treatment of hypertension, angina, migrating, asthma etc.
DE3924417A1 (en) * 1989-07-24 1991-01-31 Merck Patent Gmbh chroman
DE3926001A1 (en) * 1989-08-05 1991-02-07 Merck Patent Gmbh chroman
WO1991009031A1 (en) * 1989-12-11 1991-06-27 Beecham Group Plc Trifluoromethyl substituted compounds and a pharmaceutical composition
DE4010097A1 (en) * 1990-03-29 1991-10-02 Basf Ag UNSATURATED N-BENZOXODIAZOLOPYRANYLLACTAME, THEIR PRODUCTION AND USE
US5254578A (en) * 1990-10-24 1993-10-19 Sankyo Company, Limited Benzopyran derivatives having anti-hypertensive and vasodilatory activity and their therapeutic use
FR2698873B1 (en) 1992-12-07 1995-02-24 Lipha Benzocycloheptenes, benzoxepines and benzothiepins activators of potassium channels, preparation process, pharmaceutical composition containing them.
WO2007027959A1 (en) 2005-09-01 2007-03-08 Janssen Pharmaceutica N.V. Novel benzopyran derivatives as potassium channel openers
US7812183B2 (en) 2005-09-01 2010-10-12 Janssen Pharmaceutica Nv Benzopyran derivatives as potassium channel openers

Family Cites Families (12)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB2107706A (en) * 1981-09-25 1983-05-05 Beecham Group Plc Benzopyrans
DE3368629D1 (en) * 1982-04-28 1987-02-05 Beecham Group Plc Novel chromenes and chromans
EP0107423B1 (en) * 1982-10-19 1986-07-23 Beecham Group Plc Novel chromans and chromenes
GB8308064D0 (en) * 1983-03-24 1983-05-05 Beecham Group Plc Active compounds
GB8419516D0 (en) * 1984-07-31 1984-09-05 Beecham Group Plc Treatment
GB8625185D0 (en) * 1986-10-21 1986-11-26 Beecham Group Plc Active compounds
DE3835011A1 (en) * 1988-10-14 1990-04-19 Merck Patent Gmbh CHROME DERIVATIVES
FI90343C (en) * 1987-06-23 1994-01-25 Merck Patent Gmbh Process for the preparation of antihypertensive and antiarrhythmic trans-2,2-dimethylchroman-3-parent derivatives
AU618007B2 (en) * 1987-06-23 1991-12-12 Sanofi 2,2-dimethylchroman-3-ol derivatives, process for their preparation and pharmaceutical compositions in which they are present
FR2621587B1 (en) * 1987-10-12 1990-02-09 Sanofi Sa 2,2-DIMETHYL CHROMENE DERIVATIVES, PROCESS FOR THEIR PREPARATION AND PHARMACEUTICAL COMPOSITION CONTAINING THEM
EP0322361A3 (en) * 1987-12-23 1990-01-24 Ciba-Geigy Ag Hydrogenated 1-benzooxacycloalkyl pyridine-carboxylic-acid compounds
DE3811017A1 (en) * 1988-03-31 1989-10-19 Hoechst Ag UNSATURATED N-BENZOPYRANYLLACTAME

Cited By (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
AU618007B2 (en) * 1987-06-23 1991-12-12 Sanofi 2,2-dimethylchroman-3-ol derivatives, process for their preparation and pharmaceutical compositions in which they are present
AU619766B2 (en) * 1987-10-12 1992-02-06 Sanofi 2,2-dimethylchromene derivatives, process for their preparation and pharmaceutical compositions in which they are present
AU615275B2 (en) * 1988-03-31 1991-09-26 Hoechst Aktiengesellschaft Unsaturated N-benzopyranyllactams
US5071991A (en) * 1988-12-26 1991-12-10 Sanofi Method of preparing chroman derivatives, and synthesis intermediates
US5116987A (en) * 1988-12-26 1992-05-26 Sanofi Method of preparing chroman derivatives, and synthesis intermediates

Also Published As

Publication number Publication date
EP0273262A2 (en) 1988-07-06
JP2523343B2 (en) 1996-08-07
HU207728B (en) 1993-05-28
EP0273262A3 (en) 1989-12-06
KR880007507A (en) 1988-08-27
AU604809B2 (en) 1991-01-03
DE3726261A1 (en) 1988-07-07
KR960004828B1 (en) 1996-04-16
CA1340960C (en) 2000-04-18
HUT48621A (en) 1989-06-28
JPS63170376A (en) 1988-07-14

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Legal Events

Date Code Title Description
MK14 Patent ceased section 143(a) (annual fees not paid) or expired