AU8215391A - Diagnostic and prognostic methods based on soluble derivatives of the beta amyloid protein precursor - Google Patents
Diagnostic and prognostic methods based on soluble derivatives of the beta amyloid protein precursorInfo
- Publication number
- AU8215391A AU8215391A AU82153/91A AU8215391A AU8215391A AU 8215391 A AU8215391 A AU 8215391A AU 82153/91 A AU82153/91 A AU 82153/91A AU 8215391 A AU8215391 A AU 8215391A AU 8215391 A AU8215391 A AU 8215391A
- Authority
- AU
- Australia
- Prior art keywords
- diagnostic
- methods based
- amyloid protein
- beta amyloid
- soluble derivatives
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Abandoned
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- C07K14/46—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates
- C07K14/47—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates from mammals
- C07K14/4701—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates from mammals not used
- C07K14/4711—Alzheimer's disease; Amyloid plaque core protein
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
- G01N33/68—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving proteins, peptides or amino acids
- G01N33/6893—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving proteins, peptides or amino acids related to diseases not provided for elsewhere
- G01N33/6896—Neurological disorders, e.g. Alzheimer's disease
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N2800/00—Detection or diagnosis of diseases
- G01N2800/28—Neurological disorders
- G01N2800/2814—Dementia; Cognitive disorders
- G01N2800/2821—Alzheimer
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Engineering & Computer Science (AREA)
- Chemical & Material Sciences (AREA)
- Biomedical Technology (AREA)
- Molecular Biology (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- General Health & Medical Sciences (AREA)
- Medicinal Chemistry (AREA)
- Hematology (AREA)
- Immunology (AREA)
- Biochemistry (AREA)
- Organic Chemistry (AREA)
- Urology & Nephrology (AREA)
- Neurology (AREA)
- Cell Biology (AREA)
- Zoology (AREA)
- Physics & Mathematics (AREA)
- Analytical Chemistry (AREA)
- Microbiology (AREA)
- Biotechnology (AREA)
- General Physics & Mathematics (AREA)
- Pathology (AREA)
- Toxicology (AREA)
- Food Science & Technology (AREA)
- Gastroenterology & Hepatology (AREA)
- Biophysics (AREA)
- Genetics & Genomics (AREA)
- Neurosurgery (AREA)
- Investigating Or Analysing Biological Materials (AREA)
- Peptides Or Proteins (AREA)
- Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US54648590A | 1990-06-29 | 1990-06-29 | |
US546485 | 1990-06-29 |
Publications (1)
Publication Number | Publication Date |
---|---|
AU8215391A true AU8215391A (en) | 1992-01-23 |
Family
ID=24180644
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
AU82153/91A Abandoned AU8215391A (en) | 1990-06-29 | 1991-06-27 | Diagnostic and prognostic methods based on soluble derivatives of the beta amyloid protein precursor |
Country Status (2)
Country | Link |
---|---|
AU (1) | AU8215391A (en) |
WO (1) | WO1992000521A1 (en) |
Cited By (2)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
WO1993010459A1 (en) * | 1991-11-12 | 1993-05-27 | The University Of Melbourne | A method for assaying and treating alzheimer's disease |
AU672379B2 (en) * | 1992-04-09 | 1996-10-03 | Bayer Corporation | Diagnostic assay for Alzheimer's Disease based on the proteolysis of Alzheimer's precursor protein |
Families Citing this family (13)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
ES2236682T5 (en) | 1991-01-21 | 2011-03-31 | Elan Pharmaceuticals, Inc. | TEST AND MODEL FOR ALZHEIMER'S DISEASE. |
US5441870A (en) * | 1992-04-15 | 1995-08-15 | Athena Neurosciences, Inc. | Methods for monitoring cellular processing of β-amyloid precursor protein |
US5604102A (en) * | 1992-04-15 | 1997-02-18 | Athena Neurosciences, Inc. | Methods of screening for β-amyloid peptide production inhibitors |
US6610493B1 (en) | 1993-06-17 | 2003-08-26 | Brigham And Women's Hospital | Screening compounds for the ability to alter the production of amyloid-β peptide |
ES2203620T3 (en) * | 1992-10-26 | 2004-04-16 | Elan Pharmaceuticals, Inc. | PROCEDURES FOR THE IDENTIFICATION OF INHIBITORS OF THE PRODUCTION OF THE BETA-AMILOID PEPTIDE. |
US5605811A (en) * | 1992-10-26 | 1997-02-25 | Athena Neurosciences, Inc. | Methods and compositions for monitoring cellular processing of beta-amyloid precursor protein |
AU7556994A (en) * | 1993-08-13 | 1995-03-14 | Molecular Geriatrics Corporation | Methods for the diagnosis of alzheimer's disease |
ATE198622T1 (en) | 1993-10-27 | 2001-01-15 | Elan Pharm Inc | TRANSGENIC ANIMALS HOSTING APP ALLELES WITH THE SWEDISH MUTATION |
US5804560A (en) * | 1995-01-06 | 1998-09-08 | Sibia Neurosciences, Inc. | Peptide and peptide analog protease inhibitors |
US6017887A (en) * | 1995-01-06 | 2000-01-25 | Sibia Neurosciences, Inc. | Peptide, peptide analog and amino acid analog protease inhibitors |
US6717031B2 (en) | 1995-06-07 | 2004-04-06 | Kate Dora Games | Method for selecting a transgenic mouse model of alzheimer's disease |
FR2816411B1 (en) * | 2000-11-03 | 2003-07-04 | Inst Nat Sante Rech Med | MEANS FOR DETECTING THE PATHOLOGICAL TRANSFORMATION OF THE APP PROTEIN AND THEIR APPLICATIONS |
WO2010062904A2 (en) | 2008-11-25 | 2010-06-03 | Biogen Idec Ma Inc. | Use of dr6 and p75 antagonists to promote survival of cells of the nervous system |
-
1991
- 1991-06-27 WO PCT/US1991/004607 patent/WO1992000521A1/en unknown
- 1991-06-27 AU AU82153/91A patent/AU8215391A/en not_active Abandoned
Cited By (2)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
WO1993010459A1 (en) * | 1991-11-12 | 1993-05-27 | The University Of Melbourne | A method for assaying and treating alzheimer's disease |
AU672379B2 (en) * | 1992-04-09 | 1996-10-03 | Bayer Corporation | Diagnostic assay for Alzheimer's Disease based on the proteolysis of Alzheimer's precursor protein |
Also Published As
Publication number | Publication date |
---|---|
WO1992000521A1 (en) | 1992-01-09 |
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