AU8058398A - Enzymatic kinetic resolution of an intermediate useful for preparing substitutedtricyclics - Google Patents

Enzymatic kinetic resolution of an intermediate useful for preparing substitutedtricyclics

Info

Publication number
AU8058398A
AU8058398A AU80583/98A AU8058398A AU8058398A AU 8058398 A AU8058398 A AU 8058398A AU 80583/98 A AU80583/98 A AU 80583/98A AU 8058398 A AU8058398 A AU 8058398A AU 8058398 A AU8058398 A AU 8058398A
Authority
AU
Australia
Prior art keywords
substitutedtricyclics
preparing
kinetic resolution
intermediate useful
enzymatic kinetic
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Abandoned
Application number
AU80583/98A
Other languages
English (en)
Inventor
Jinchu Liu
William Brian Morgan
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Merck Sharp and Dohme LLC
Original Assignee
Schering Corp
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Schering Corp filed Critical Schering Corp
Publication of AU8058398A publication Critical patent/AU8058398A/en
Abandoned legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
    • C12P41/00—Processes using enzymes or microorganisms to separate optical isomers from a racemic mixture
    • C12P41/006—Processes using enzymes or microorganisms to separate optical isomers from a racemic mixture by reactions involving C-N bonds, e.g. nitriles, amides, hydantoins, carbamates, lactames, transamination reactions, or keto group formation from racemic mixtures
    • C12P41/007—Processes using enzymes or microorganisms to separate optical isomers from a racemic mixture by reactions involving C-N bonds, e.g. nitriles, amides, hydantoins, carbamates, lactames, transamination reactions, or keto group formation from racemic mixtures by reactions involving acyl derivatives of racemic amines
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
    • C12P17/00—Preparation of heterocyclic carbon compounds with only O, N, S, Se or Te as ring hetero atoms
    • C12P17/16—Preparation of heterocyclic carbon compounds with only O, N, S, Se or Te as ring hetero atoms containing two or more hetero rings
    • C12P17/165—Heterorings having nitrogen atoms as the only ring heteroatoms

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Zoology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Wood Science & Technology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Microbiology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Biotechnology (AREA)
  • Health & Medical Sciences (AREA)
  • Biochemistry (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • General Engineering & Computer Science (AREA)
  • General Health & Medical Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Analytical Chemistry (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Plural Heterocyclic Compounds (AREA)
AU80583/98A 1997-06-17 1998-06-15 Enzymatic kinetic resolution of an intermediate useful for preparing substitutedtricyclics Abandoned AU8058398A (en)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US87767597A 1997-06-17 1997-06-17
US08877675 1997-06-17
PCT/US1998/011501 WO1998058073A1 (en) 1997-06-17 1998-06-15 Enzymatic kinetic resolution of an intermediate useful for preparing substituted tricyclics

Publications (1)

Publication Number Publication Date
AU8058398A true AU8058398A (en) 1999-01-04

Family

ID=25370483

Family Applications (1)

Application Number Title Priority Date Filing Date
AU80583/98A Abandoned AU8058398A (en) 1997-06-17 1998-06-15 Enzymatic kinetic resolution of an intermediate useful for preparing substitutedtricyclics

Country Status (9)

Country Link
EP (1) EP1002123A1 (enEXAMPLES)
JP (1) JP3421355B2 (enEXAMPLES)
AR (1) AR015892A1 (enEXAMPLES)
AU (1) AU8058398A (enEXAMPLES)
CA (1) CA2293708C (enEXAMPLES)
IN (1) IN187248B (enEXAMPLES)
MY (1) MY133532A (enEXAMPLES)
WO (1) WO1998058073A1 (enEXAMPLES)
ZA (1) ZA985217B (enEXAMPLES)

Families Citing this family (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP1091954B1 (en) * 1998-07-02 2003-03-12 Schering Corporation Process for producing (8-chloro-3,10-dibromo-6,11-dihydro-5h-benzo 5,6]cyclohepta[1,2-b]pyridin-11-yl)-1-piperidine
US6706883B1 (en) 1998-07-02 2004-03-16 Schering Corporation Process for producing (8-chloro-3,10-dibromo-6,11-dihydro-5H-benzo[5,6]cyclohepta[1,2-B]pyridin-11-YL)-1-piperdine
EP1156120B1 (en) 2000-05-08 2006-11-22 Pfizer Products Inc. Enzymatic resolution of selective estrogen receptor modulators

Also Published As

Publication number Publication date
JP3421355B2 (ja) 2003-06-30
IN187248B (enEXAMPLES) 2002-03-09
AR015892A1 (es) 2001-05-30
ZA985217B (en) 1999-01-07
CA2293708A1 (en) 1998-12-23
WO1998058073A1 (en) 1998-12-23
JP2000512862A (ja) 2000-10-03
EP1002123A1 (en) 2000-05-24
CA2293708C (en) 2004-05-11
MY133532A (en) 2007-11-30

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Legal Events

Date Code Title Description
MK6 Application lapsed section 142(2)(f)/reg. 8.3(3) - pct applic. not entering national phase