AU7983400A - Improvement of clavulanic acid production - Google Patents

Improvement of clavulanic acid production

Info

Publication number
AU7983400A
AU7983400A AU79834/00A AU7983400A AU7983400A AU 7983400 A AU7983400 A AU 7983400A AU 79834/00 A AU79834/00 A AU 79834/00A AU 7983400 A AU7983400 A AU 7983400A AU 7983400 A AU7983400 A AU 7983400A
Authority
AU
Australia
Prior art keywords
improvement
acid production
clavulanic acid
clavulanic
production
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Abandoned
Application number
AU79834/00A
Inventor
Nusrat Khaleeli
Rongfeng Li
Craig A Townsend
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Johns Hopkins University
Original Assignee
Johns Hopkins University
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Johns Hopkins University filed Critical Johns Hopkins University
Publication of AU7983400A publication Critical patent/AU7983400A/en
Abandoned legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09—Recombinant DNA-technology
    • C12N15/63—Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression
    • C12N15/74—Vectors or expression systems specially adapted for prokaryotic hosts other than E. coli, e.g. Lactobacillus, Micromonospora
    • C12N15/76—Vectors or expression systems specially adapted for prokaryotic hosts other than E. coli, e.g. Lactobacillus, Micromonospora for Actinomyces; for Streptomyces
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
    • C12P17/00—Preparation of heterocyclic carbon compounds with only O, N, S, Se or Te as ring hetero atoms
    • C12P17/18—Preparation of heterocyclic carbon compounds with only O, N, S, Se or Te as ring hetero atoms containing at least two hetero rings condensed among themselves or condensed with a common carbocyclic ring system, e.g. rifamycin
    • C12P17/188—Heterocyclic compound containing in the condensed system at least one hetero ring having nitrogen atoms and oxygen atoms as the only ring heteroatoms

Landscapes

  • Genetics & Genomics (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Zoology (AREA)
  • Wood Science & Technology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Biotechnology (AREA)
  • General Engineering & Computer Science (AREA)
  • Biomedical Technology (AREA)
  • Microbiology (AREA)
  • Biochemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Plant Pathology (AREA)
  • Molecular Biology (AREA)
  • Biophysics (AREA)
  • Physics & Mathematics (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Enzymes And Modification Thereof (AREA)
AU79834/00A 1999-09-16 2000-09-15 Improvement of clavulanic acid production Abandoned AU7983400A (en)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US15421399P 1999-09-16 1999-09-16
US60154213 1999-09-16
PCT/US2000/025186 WO2001019959A1 (en) 1999-09-16 2000-09-15 Improvement of clavulanic acid production

Publications (1)

Publication Number Publication Date
AU7983400A true AU7983400A (en) 2001-04-17

Family

ID=22550464

Family Applications (1)

Application Number Title Priority Date Filing Date
AU79834/00A Abandoned AU7983400A (en) 1999-09-16 2000-09-15 Improvement of clavulanic acid production

Country Status (4)

Country Link
EP (1) EP1218486A4 (en)
AU (1) AU7983400A (en)
HK (1) HK1047957A1 (en)
WO (1) WO2001019959A1 (en)

Families Citing this family (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN100355895C (en) * 2004-12-17 2007-12-19 天津科技大学 Plasmid with bar streptomycete Lat gene loss, derivative and constructing method thereof

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB8813055D0 (en) * 1988-06-02 1988-07-06 Beecham Group Plc Novel substance
EP0673432B1 (en) * 1992-12-02 1999-03-24 Smithkline Beecham Plc Process for preparing clavulanic acid
CA2108113C (en) * 1993-10-08 2006-12-05 Susan E. Jensen Dna sequence encoding enzymes of clavulanic acid biosynthesis
GB9702218D0 (en) * 1997-02-04 1997-03-26 Smithkline Beecham Plc Novel product
ES2131001B1 (en) * 1997-06-16 2000-04-01 Antibioticos Sau PROCEDURE TO INCREASE THE PRODUCTION OF CLAVULANIC ACID THROUGH THE EXPRESSION OF REGULATORY AND BIOSYNTHETIC GENES OF STREPTOMYCES CLAVULIGERUS.

Also Published As

Publication number Publication date
EP1218486A1 (en) 2002-07-03
WO2001019959A1 (en) 2001-03-22
EP1218486A4 (en) 2002-11-04
HK1047957A1 (en) 2003-03-14

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Legal Events

Date Code Title Description
MK6 Application lapsed section 142(2)(f)/reg. 8.3(3) - pct applic. not entering national phase