AU762986B2 - Combination therapy using nucleic acids and conventional drugs - Google Patents

Combination therapy using nucleic acids and conventional drugs Download PDF

Info

Publication number
AU762986B2
AU762986B2 AU35912/99A AU3591299A AU762986B2 AU 762986 B2 AU762986 B2 AU 762986B2 AU 35912/99 A AU35912/99 A AU 35912/99A AU 3591299 A AU3591299 A AU 3591299A AU 762986 B2 AU762986 B2 AU 762986B2
Authority
AU
Australia
Prior art keywords
nucleic acid
cells
lipid
cell cycle
cell
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired
Application number
AU35912/99A
Other languages
English (en)
Other versions
AU3591299A (en
Inventor
Roger W. Graham
Phalgun B. Joshi
Ian Maclachlan
Ian C. Mortimer
Patrick M.S. Tam
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Inex Pharmaceuticals Corp
Original Assignee
Inex Pharmaceuticals Corp
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from US09/295,663 external-priority patent/US6841537B1/en
Application filed by Inex Pharmaceuticals Corp filed Critical Inex Pharmaceuticals Corp
Publication of AU3591299A publication Critical patent/AU3591299A/en
Application granted granted Critical
Publication of AU762986B2 publication Critical patent/AU762986B2/en
Anticipated expiration legal-status Critical
Expired legal-status Critical Current

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K48/00—Medicinal preparations containing genetic material which is inserted into cells of the living body to treat genetic diseases; Gene therapy
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K41/00—Medicinal preparations obtained by treating materials with wave energy or particle radiation ; Therapies using these preparations
    • A61K41/0038—Radiosensitizing, i.e. administration of pharmaceutical agents that enhance the effect of radiotherapy
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09—Recombinant DNA-technology
    • C12N15/87—Introduction of foreign genetic material using processes not otherwise provided for, e.g. co-transformation

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Genetics & Genomics (AREA)
  • General Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Medicinal Chemistry (AREA)
  • Organic Chemistry (AREA)
  • Veterinary Medicine (AREA)
  • Biotechnology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • General Engineering & Computer Science (AREA)
  • Molecular Biology (AREA)
  • Epidemiology (AREA)
  • Wood Science & Technology (AREA)
  • Biomedical Technology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Zoology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Plant Pathology (AREA)
  • Biophysics (AREA)
  • Microbiology (AREA)
  • Physics & Mathematics (AREA)
  • Biochemistry (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
AU35912/99A 1998-04-22 1999-04-22 Combination therapy using nucleic acids and conventional drugs Expired AU762986B2 (en)

Applications Claiming Priority (7)

Application Number Priority Date Filing Date Title
US8266598P 1998-04-22 1998-04-22
US60/082665 1998-04-22
US11163598P 1998-12-09 1998-12-09
US60/111635 1998-12-09
US09/295663 1999-04-21
US09/295,663 US6841537B1 (en) 1998-04-22 1999-04-21 Combination therapy using nucleic acids and conventional drugs
PCT/CA1999/000371 WO1999054445A2 (fr) 1998-04-22 1999-04-22 Traitement associe utilisant des acides nucleiques et des medicaments classiques

Publications (2)

Publication Number Publication Date
AU3591299A AU3591299A (en) 1999-11-08
AU762986B2 true AU762986B2 (en) 2003-07-10

Family

ID=27374309

Family Applications (1)

Application Number Title Priority Date Filing Date
AU35912/99A Expired AU762986B2 (en) 1998-04-22 1999-04-22 Combination therapy using nucleic acids and conventional drugs

Country Status (5)

Country Link
EP (1) EP1082419A2 (fr)
JP (1) JP2002512258A (fr)
AU (1) AU762986B2 (fr)
CA (1) CA2325561A1 (fr)
WO (1) WO1999054445A2 (fr)

Families Citing this family (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2001066144A2 (fr) 2000-03-08 2001-09-13 Rhode Island Hospital, A Lifespan Partner Therapie d'association de medicaments
US7294511B2 (en) 2001-03-22 2007-11-13 Chromos Molecular Systems, Inc. Methods for delivering nucleic acid molecules into cells and assessment thereof
US6936469B2 (en) 2001-03-22 2005-08-30 Chromos Molecular Systems Inc. Methods for delivering nucleic acid molecules into cells and assessment thereof
AU2003221584A1 (en) * 2002-05-01 2003-11-17 Chromos Molecular Systems, Inc. Methods for delivering nucleic acid molecules into cells and assessment thereof

Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO1997039135A1 (fr) * 1996-04-17 1997-10-23 Board Of Regents, The University Of Texas System Expression renforcee de transgenes
AU6438098A (en) * 1997-02-18 1998-09-08 Canji, Inc. Combined tumor suppressor gene therapy and chemotherapy in the treatment of neoplasms

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4029663A (en) * 1975-07-10 1977-06-14 Eli Lilly And Company Dimeric anhydro-vinca derivatives
CA2138124A1 (fr) * 1992-06-24 1994-01-06 David D. Eveleth, Jr. Utilisation d'inhibiteurs de la calpaine pour inhiber et traiter des affections medicales associees a une augmentation de l'activite de la calpaine
CA2129282A1 (fr) * 1993-09-29 1995-03-30 George Weber Methode de traitement des maladies neoplasiques a l'aide du taxol et du triazofurin
US5688773A (en) * 1994-08-17 1997-11-18 The General Hospital Corporation Method of selectively destroying neoplastic cells

Patent Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO1997039135A1 (fr) * 1996-04-17 1997-10-23 Board Of Regents, The University Of Texas System Expression renforcee de transgenes
AU6438098A (en) * 1997-02-18 1998-09-08 Canji, Inc. Combined tumor suppressor gene therapy and chemotherapy in the treatment of neoplasms

Non-Patent Citations (1)

* Cited by examiner, † Cited by third party
Title
IMMUNOLOGY LETTERS, 57(1997) PP 19-25, CHRIST ET AL. *

Also Published As

Publication number Publication date
AU3591299A (en) 1999-11-08
CA2325561A1 (fr) 1999-10-28
WO1999054445A3 (fr) 1999-12-09
JP2002512258A (ja) 2002-04-23
EP1082419A2 (fr) 2001-03-14
WO1999054445A2 (fr) 1999-10-28

Similar Documents

Publication Publication Date Title
AU749881B2 (en) Systemic delivery of serum stable plasmid lipid particles for cancer therapy
US20050118253A1 (en) Systemic delivery of serum stable plasmid lipid particles for cancer therapy
US5705385A (en) Lipid-nucleic acid particles prepared via a hydrophobic lipid-nucleic acid complex intermediate and use for gene transfer
Roth et al. Gene therapy for cancer: what have we done and where are we going?
US5965542A (en) Use of temperature to control the size of cationic liposome/plasmid DNA complexes
EP1328254B1 (fr) Formulations de lipides pour une administration ciblee
CA2309727C (fr) Methodes d'encapsulation d'acides nucleiques dans des bicouches lipidiques
JP2010263920A (ja) 標的化リポゾーム遺伝子送達
CA2134773A1 (fr) Methodes et compositions pour genotherapie in vivo
US6841537B1 (en) Combination therapy using nucleic acids and conventional drugs
Isomoto et al. Heat-directed suicide gene therapy mediated by heat shock protein promoter for gastric cancer
Hofland et al. Inhibition of human ovarian carcinoma cell proliferation by liposome-plasmid DNA complex
AU762986B2 (en) Combination therapy using nucleic acids and conventional drugs
AU737720B2 (en) Formulation of stabilized cationic transfection agent(s)/nucleic acid particles
AU754244B2 (en) Combination therapy using nucleic acids and radio therapy
AU2003201008B2 (en) Methods for Encapsulating Nucleic Acids in Lipid Bilayers
MXPA99006783A (en) Formulation of stabilised cationic transfection agent(s)/nucleic acid particles

Legal Events

Date Code Title Description
FGA Letters patent sealed or granted (standard patent)
MK14 Patent ceased section 143(a) (annual fees not paid) or expired