AU744150B2 - NK cell activation inducing ligand (nail) DNA and polypeptides, and use thereof - Google Patents
NK cell activation inducing ligand (nail) DNA and polypeptides, and use thereof Download PDFInfo
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- AU744150B2 AU744150B2 AU31970/99A AU3197099A AU744150B2 AU 744150 B2 AU744150 B2 AU 744150B2 AU 31970/99 A AU31970/99 A AU 31970/99A AU 3197099 A AU3197099 A AU 3197099A AU 744150 B2 AU744150 B2 AU 744150B2
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- 230000002441 reversible effect Effects 0.000 description 1
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- 238000005185 salting out Methods 0.000 description 1
- 238000009738 saturating Methods 0.000 description 1
- 230000003248 secreting effect Effects 0.000 description 1
- 238000002864 sequence alignment Methods 0.000 description 1
- 239000013605 shuttle vector Substances 0.000 description 1
- 230000007727 signaling mechanism Effects 0.000 description 1
- 230000037432 silent mutation Effects 0.000 description 1
- 239000000741 silica gel Substances 0.000 description 1
- 229910002027 silica gel Inorganic materials 0.000 description 1
- 238000002741 site-directed mutagenesis Methods 0.000 description 1
- 238000001542 size-exclusion chromatography Methods 0.000 description 1
- 210000002027 skeletal muscle Anatomy 0.000 description 1
- 210000000813 small intestine Anatomy 0.000 description 1
- 239000011780 sodium chloride Substances 0.000 description 1
- 238000010532 solid phase synthesis reaction Methods 0.000 description 1
- 239000002904 solvent Substances 0.000 description 1
- 125000006850 spacer group Chemical group 0.000 description 1
- 230000003393 splenic effect Effects 0.000 description 1
- 210000000130 stem cell Anatomy 0.000 description 1
- 238000007920 subcutaneous administration Methods 0.000 description 1
- 238000013268 sustained release Methods 0.000 description 1
- 239000012730 sustained-release form Substances 0.000 description 1
- 230000002194 synthesizing effect Effects 0.000 description 1
- 239000012622 synthetic inhibitor Substances 0.000 description 1
- 229920003002 synthetic resin Polymers 0.000 description 1
- 238000004885 tandem mass spectrometry Methods 0.000 description 1
- 210000001550 testis Anatomy 0.000 description 1
- 229960002180 tetracycline Drugs 0.000 description 1
- 229930101283 tetracycline Natural products 0.000 description 1
- 235000019364 tetracycline Nutrition 0.000 description 1
- 150000003522 tetracyclines Chemical class 0.000 description 1
- 230000001225 therapeutic effect Effects 0.000 description 1
- RTKIYNMVFMVABJ-UHFFFAOYSA-L thimerosal Chemical compound [Na+].CC[Hg]SC1=CC=CC=C1C([O-])=O RTKIYNMVFMVABJ-UHFFFAOYSA-L 0.000 description 1
- 229940033663 thimerosal Drugs 0.000 description 1
- 229940104230 thymidine Drugs 0.000 description 1
- 210000001541 thymus gland Anatomy 0.000 description 1
- 229960001479 tosylchloramide sodium Drugs 0.000 description 1
- 230000005026 transcription initiation Effects 0.000 description 1
- 230000005030 transcription termination Effects 0.000 description 1
- 230000001131 transforming effect Effects 0.000 description 1
- 230000010474 transient expression Effects 0.000 description 1
- 230000014621 translational initiation Effects 0.000 description 1
- 229930013292 trichothecene Natural products 0.000 description 1
- 150000003327 trichothecene derivatives Chemical class 0.000 description 1
- LENZDBCJOHFCAS-UHFFFAOYSA-N tris Chemical compound OCC(N)(CO)CO LENZDBCJOHFCAS-UHFFFAOYSA-N 0.000 description 1
- 230000005909 tumor killing Effects 0.000 description 1
- 102000003390 tumor necrosis factor Human genes 0.000 description 1
- 230000007306 turnover Effects 0.000 description 1
- 238000000108 ultra-filtration Methods 0.000 description 1
- 230000009452 underexpressoin Effects 0.000 description 1
- 241001529453 unidentified herpesvirus Species 0.000 description 1
- LSGOVYNHVSXFFJ-UHFFFAOYSA-N vanadate(3-) Chemical compound [O-][V]([O-])([O-])=O LSGOVYNHVSXFFJ-UHFFFAOYSA-N 0.000 description 1
- 230000003442 weekly effect Effects 0.000 description 1
- 238000002424 x-ray crystallography Methods 0.000 description 1
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Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- C07K14/705—Receptors; Cell surface antigens; Cell surface determinants
- C07K14/70503—Immunoglobulin superfamily
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2319/00—Fusion polypeptide
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2319/00—Fusion polypeptide
- C07K2319/30—Non-immunoglobulin-derived peptide or protein having an immunoglobulin constant or Fc region, or a fragment thereof, attached thereto
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Organic Chemistry (AREA)
- Medicinal Chemistry (AREA)
- General Health & Medical Sciences (AREA)
- Immunology (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- General Chemical & Material Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Animal Behavior & Ethology (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Zoology (AREA)
- Biophysics (AREA)
- Cell Biology (AREA)
- Toxicology (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Gastroenterology & Hepatology (AREA)
- Biochemistry (AREA)
- Engineering & Computer Science (AREA)
- Genetics & Genomics (AREA)
- Molecular Biology (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Micro-Organisms Or Cultivation Processes Thereof (AREA)
- Peptides Or Proteins (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
Applications Claiming Priority (5)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US7984598P | 1998-03-27 | 1998-03-27 | |
| US60/079845 | 1998-03-27 | ||
| US9675098P | 1998-08-17 | 1998-08-17 | |
| US60/096750 | 1998-08-17 | ||
| PCT/US1999/006215 WO1999050297A1 (en) | 1998-03-27 | 1999-03-23 | Nk cell activation inducing ligand (nail) dna and polypeptides, and use thereof |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| AU3197099A AU3197099A (en) | 1999-10-18 |
| AU744150B2 true AU744150B2 (en) | 2002-02-14 |
Family
ID=26762494
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| AU31970/99A Ceased AU744150B2 (en) | 1998-03-27 | 1999-03-23 | NK cell activation inducing ligand (nail) DNA and polypeptides, and use thereof |
Country Status (8)
| Country | Link |
|---|---|
| US (1) | US20080081043A1 (https=) |
| EP (1) | EP1064307A1 (https=) |
| JP (1) | JP2002509712A (https=) |
| AU (1) | AU744150B2 (https=) |
| CA (1) | CA2323524A1 (https=) |
| IL (2) | IL138410A0 (https=) |
| NZ (1) | NZ507641A (https=) |
| WO (1) | WO1999050297A1 (https=) |
Families Citing this family (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| WO2000073333A2 (en) * | 1999-05-28 | 2000-12-07 | Immunex Corporation | Ligand for cd7, and methods for use thereof |
| IL160157A0 (en) | 2001-08-17 | 2004-07-25 | Coley Pharm Group Inc | Combination motif immune stimulation oligonucleotides with improved activity |
| CN106103701B (zh) * | 2014-01-03 | 2020-04-24 | 中央研究院 | 改造的自然杀手细胞及其组成与用途 |
Citations (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US5688690A (en) * | 1994-09-16 | 1997-11-18 | The Wistar Institute Of Anatomy And Biology | Human cytotoxic lymphocyte signal transduction surface protein (P38) and monoclonal antibodies thereto |
Family Cites Families (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| ATE300615T1 (de) | 1990-08-29 | 2005-08-15 | Genpharm Int | Transgene mäuse fähig zur produktion heterologer antikörper |
| WO2013128474A1 (en) | 2012-03-02 | 2013-09-06 | Council Of Scientific & Industrial Research | Double fortified salt composition containing iron and iodine and process for the preparation thereof |
-
1999
- 1999-03-23 IL IL13841099A patent/IL138410A0/xx not_active IP Right Cessation
- 1999-03-23 NZ NZ507641A patent/NZ507641A/en unknown
- 1999-03-23 JP JP2000541199A patent/JP2002509712A/ja active Pending
- 1999-03-23 AU AU31970/99A patent/AU744150B2/en not_active Ceased
- 1999-03-23 WO PCT/US1999/006215 patent/WO1999050297A1/en not_active Ceased
- 1999-03-23 CA CA002323524A patent/CA2323524A1/en not_active Abandoned
- 1999-03-23 EP EP99914030A patent/EP1064307A1/en not_active Withdrawn
-
2000
- 2000-09-12 IL IL138410A patent/IL138410A/en unknown
-
2007
- 2007-07-03 US US11/824,835 patent/US20080081043A1/en not_active Abandoned
Patent Citations (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US5688690A (en) * | 1994-09-16 | 1997-11-18 | The Wistar Institute Of Anatomy And Biology | Human cytotoxic lymphocyte signal transduction surface protein (P38) and monoclonal antibodies thereto |
Non-Patent Citations (1)
| Title |
|---|
| P.A. MATHEW ET AL. J.IMMUNOLOGY V151(10), P5328-5337 1993 * |
Also Published As
| Publication number | Publication date |
|---|---|
| CA2323524A1 (en) | 1999-10-07 |
| JP2002509712A (ja) | 2002-04-02 |
| US20080081043A1 (en) | 2008-04-03 |
| EP1064307A1 (en) | 2001-01-03 |
| AU3197099A (en) | 1999-10-18 |
| WO1999050297A1 (en) | 1999-10-07 |
| IL138410A (en) | 2008-07-08 |
| IL138410A0 (en) | 2001-10-31 |
| NZ507641A (en) | 2003-09-26 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| FGA | Letters patent sealed or granted (standard patent) |