AU7397587A - A prodrug form of 5-fluorouracil and a method of treatment of cancer - Google Patents

A prodrug form of 5-fluorouracil and a method of treatment of cancer

Info

Publication number
AU7397587A
AU7397587A AU73975/87A AU7397587A AU7397587A AU 7397587 A AU7397587 A AU 7397587A AU 73975/87 A AU73975/87 A AU 73975/87A AU 7397587 A AU7397587 A AU 7397587A AU 7397587 A AU7397587 A AU 7397587A
Authority
AU
Australia
Prior art keywords
fluorouracil
cancer
treatment
prodrug form
prodrug
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Abandoned
Application number
AU73975/87A
Inventor
Hans Bundgaard
Anders Buur
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Farmaceutisk Laboratorium Ferring AS
Original Assignee
Farmaceutisk Laboratorium Ferring AS
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Farmaceutisk Laboratorium Ferring AS filed Critical Farmaceutisk Laboratorium Ferring AS
Publication of AU7397587A publication Critical patent/AU7397587A/en
Abandoned legal-status Critical Current

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D239/00Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings
    • C07D239/02Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings
    • C07D239/24Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings having three or more double bonds between ring members or between ring members and non-ring members
    • C07D239/28Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings having three or more double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, directly attached to ring carbon atoms
    • C07D239/46Two or more oxygen, sulphur or nitrogen atoms
    • C07D239/52Two oxygen atoms
    • C07D239/54Two oxygen atoms as doubly bound oxygen atoms or as unsubstituted hydroxy radicals
    • C07D239/545Two oxygen atoms as doubly bound oxygen atoms or as unsubstituted hydroxy radicals with other hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, directly attached to ring carbon atoms
    • C07D239/553Two oxygen atoms as doubly bound oxygen atoms or as unsubstituted hydroxy radicals with other hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, directly attached to ring carbon atoms with halogen atoms or nitro radicals directly attached to ring carbon atoms, e.g. fluorouracil

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
AU73975/87A 1986-04-30 1987-04-29 A prodrug form of 5-fluorouracil and a method of treatment of cancer Abandoned AU7397587A (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
DK1974/86 1986-04-30
DK197486A DK197486A (en) 1986-04-30 1986-04-30 5-FLUORURACIL PRODUCT

Publications (1)

Publication Number Publication Date
AU7397587A true AU7397587A (en) 1987-11-24

Family

ID=8109215

Family Applications (1)

Application Number Title Priority Date Filing Date
AU73975/87A Abandoned AU7397587A (en) 1986-04-30 1987-04-29 A prodrug form of 5-fluorouracil and a method of treatment of cancer

Country Status (4)

Country Link
EP (1) EP0265506A1 (en)
AU (1) AU7397587A (en)
DK (1) DK197486A (en)
WO (1) WO1987006581A1 (en)

Families Citing this family (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US20040152769A1 (en) * 2002-11-09 2004-08-05 Ekwuribe Nnochiri Nkem Modified carbamate-containing prodrugs and methods of synthesizing same
WO2010107487A2 (en) * 2009-03-18 2010-09-23 Wu Nian Lipid-drug conjugates for drug delivery

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS6024789B2 (en) * 1976-09-03 1985-06-14 小野薬品工業株式会社 5-Fluorouracil derivative compound
JPS5331676A (en) * 1976-09-06 1978-03-25 Mitsui Toatsu Chem Inc Uracil derivatives and their preparation
JPS6052708B2 (en) * 1976-12-24 1985-11-20 エーザイ株式会社 5-Fluorouracil compounds and antitumor agents containing them
AU523746B2 (en) * 1977-04-05 1982-08-12 Taiho Pharmaceutical Co., Ltd. Anticancer composition
JPS62174060A (en) * 1985-10-11 1987-07-30 Terumo Corp 5-fluorouracil derivative and drug preparation containing same

Also Published As

Publication number Publication date
EP0265506A1 (en) 1988-05-04
WO1987006581A1 (en) 1987-11-05
DK197486D0 (en) 1986-04-30
DK197486A (en) 1987-10-31

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