AU7257994A - Novel protein inhibitors of serine proteinases (e.g. furin) derived from turkey ovomucoid third domain - Google Patents

Novel protein inhibitors of serine proteinases (e.g. furin) derived from turkey ovomucoid third domain

Info

Publication number
AU7257994A
AU7257994A AU72579/94A AU7257994A AU7257994A AU 7257994 A AU7257994 A AU 7257994A AU 72579/94 A AU72579/94 A AU 72579/94A AU 7257994 A AU7257994 A AU 7257994A AU 7257994 A AU7257994 A AU 7257994A
Authority
AU
Australia
Prior art keywords
furin
domain
derived
novel protein
protein inhibitors
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Abandoned
Application number
AU72579/94A
Inventor
Stephen Anderson
Michael Laskowski
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Individual
Original Assignee
Individual
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Individual filed Critical Individual
Publication of AU7257994A publication Critical patent/AU7257994A/en
Abandoned legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
    • C12N9/14—Hydrolases (3)
    • C12N9/48—Hydrolases (3) acting on peptide bonds (3.4)
    • C12N9/50—Proteinases, e.g. Endopeptidases (3.4.21-3.4.25)
    • C12N9/64—Proteinases, e.g. Endopeptidases (3.4.21-3.4.25) derived from animal tissue
    • C12N9/6421—Proteinases, e.g. Endopeptidases (3.4.21-3.4.25) derived from animal tissue from mammals
    • C12N9/6424—Serine endopeptidases (3.4.21)
    • C12N9/6454—Dibasic site splicing serine proteases, e.g. kexin (3.4.21.61); furin (3.4.21.75) and other proprotein convertases
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/81—Protease inhibitors
    • C07K14/8107—Endopeptidase (E.C. 3.4.21-99) inhibitors
    • C07K14/811—Serine protease (E.C. 3.4.21) inhibitors
    • C07K14/8135—Kazal type inhibitors, e.g. pancreatic secretory inhibitor, ovomucoid
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2319/00—Fusion polypeptide
AU72579/94A 1993-07-09 1994-07-08 Novel protein inhibitors of serine proteinases (e.g. furin) derived from turkey ovomucoid third domain Abandoned AU7257994A (en)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US8924893A 1993-07-09 1993-07-09
US089248 1993-07-09
PCT/US1994/007779 WO1995002055A1 (en) 1993-07-09 1994-07-08 Novel protein inhibitors of serine proteinases (e.g. furin) derived from turkey ovomucoid third domain

Publications (1)

Publication Number Publication Date
AU7257994A true AU7257994A (en) 1995-02-06

Family

ID=22216550

Family Applications (1)

Application Number Title Priority Date Filing Date
AU72579/94A Abandoned AU7257994A (en) 1993-07-09 1994-07-08 Novel protein inhibitors of serine proteinases (e.g. furin) derived from turkey ovomucoid third domain

Country Status (2)

Country Link
AU (1) AU7257994A (en)
WO (1) WO1995002055A1 (en)

Families Citing this family (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
BR9711540A (en) * 1996-09-24 2001-06-19 Protector & Gamble Company Protein stabilized protease inhibitors and variants thereof
ES2241197T3 (en) * 1997-12-23 2005-10-16 Pharis Biotec Gmbh SERINA-PROTEASA INHIBITORS.
EP1475435A1 (en) * 2003-05-09 2004-11-10 Max-Planck-Gesellschaft zur Förderung der Wissenschaften e.V. Prohormone/proprotein-proteinase crystal structure and use thereof
CN1908010B (en) * 2005-08-05 2012-02-29 同济大学 Furin enzyme inhibitor of resisting HIV-1 and preparation method thereof

Family Cites Families (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR2599752B1 (en) * 1986-06-10 1989-11-03 Transgene Sa ALPHA1- ANTITRYPSIN VARIANTS USEFUL IN PARTICULAR AS KALLIKREIN INHIBITORS

Also Published As

Publication number Publication date
WO1995002055A1 (en) 1995-01-19

Similar Documents

Publication Publication Date Title
CY2317B1 (en) Thf-containing sulfonamide inhibitors of aspartyl protease.
GR3030719T3 (en) Sulfonamide inhibitors of hiv-aspartyl protease.
AU1381499A (en) Cell-permeable protein inhibitors of calpain
EP0772590A1 (en) Thrombin inhibitors
AP9701054A0 (en) Inhibitors of cycteine protease
AU7117496A (en) Peptide inhibitor for viral protease derived from the transframe region of the gag-pol gene
ES2172657T3 (en) THROMBIN INHIBITORS.
HK1009811A1 (en) Oxygenated-heterocycle containing sulfonamide inhibitors of aspartyl protease
HK1023779A1 (en) Inhibitors of serine proteases, particularly hepatitis c virus ns3 protease
NO983688D0 (en) Serine protease inhibitors
PL328665A1 (en) Inhibitors of serinic protease
HK1016495A1 (en) Phosphorous-containing cysteine and serine protease inhibitors
NO983991D0 (en) Serine protease inhibitors
SI0932617T1 (en) Inhibitors of serine proteases, particularly hepatitis c virus ns3 protease
AU3334595A (en) Assay for the detection of proteases
AU6877998A (en) Dipeptide inhibitors of protein farnesyltransferase
WO1997008934A3 (en) Aryl acrylic acid derivatives useful as protein tyrosine phosphatase inhibitors
AU7257994A (en) Novel protein inhibitors of serine proteinases (e.g. furin) derived from turkey ovomucoid third domain
GB2299583B (en) Peptidyl inhibitors of serine proteases
IL118323A0 (en) Imadazo (1,5-a) pyridine derived serine protease inhibitors
AU2234497A (en) Novel protease inhibitors derived from guamerin
GB9405905D0 (en) Inhibitors of isoprenylated protein endoprotease
AU6967296A (en) Inhibitors of pepsin or pepsin-like proteinases as acaricides
ATE313624T1 (en) BACILLUS PROTEASES
ZA969078B (en) Inhibitors of cysteine protease.