AU7240291A - Process and device for the simultaneous synthesis of several polypeptides - Google Patents
Process and device for the simultaneous synthesis of several polypeptidesInfo
- Publication number
- AU7240291A AU7240291A AU72402/91A AU7240291A AU7240291A AU 7240291 A AU7240291 A AU 7240291A AU 72402/91 A AU72402/91 A AU 72402/91A AU 7240291 A AU7240291 A AU 7240291A AU 7240291 A AU7240291 A AU 7240291A
- Authority
- AU
- Australia
- Prior art keywords
- simultaneous synthesis
- several polypeptides
- polypeptides
- several
- simultaneous
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
Links
Classifications
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- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K1/00—General methods for the preparation of peptides, i.e. processes for the organic chemical preparation of peptides or proteins of any length
- C07K1/04—General methods for the preparation of peptides, i.e. processes for the organic chemical preparation of peptides or proteins of any length on carriers
- C07K1/045—General methods for the preparation of peptides, i.e. processes for the organic chemical preparation of peptides or proteins of any length on carriers using devices to improve synthesis, e.g. reactors, special vessels
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01J—CHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY; THEIR RELEVANT APPARATUS
- B01J19/00—Chemical, physical or physico-chemical processes in general; Their relevant apparatus
- B01J19/0046—Sequential or parallel reactions, e.g. for the synthesis of polypeptides or polynucleotides; Apparatus and devices for combinatorial chemistry or for making molecular arrays
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01J—CHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY; THEIR RELEVANT APPARATUS
- B01J2219/00—Chemical, physical or physico-chemical processes in general; Their relevant apparatus
- B01J2219/00274—Sequential or parallel reactions; Apparatus and devices for combinatorial chemistry or for making arrays; Chemical library technology
- B01J2219/00277—Apparatus
- B01J2219/00279—Features relating to reactor vessels
- B01J2219/00281—Individual reactor vessels
- B01J2219/00286—Reactor vessels with top and bottom openings
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- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01J—CHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY; THEIR RELEVANT APPARATUS
- B01J2219/00—Chemical, physical or physico-chemical processes in general; Their relevant apparatus
- B01J2219/00274—Sequential or parallel reactions; Apparatus and devices for combinatorial chemistry or for making arrays; Chemical library technology
- B01J2219/00277—Apparatus
- B01J2219/00279—Features relating to reactor vessels
- B01J2219/00306—Reactor vessels in a multiple arrangement
- B01J2219/00308—Reactor vessels in a multiple arrangement interchangeably mounted in racks or blocks
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01J—CHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY; THEIR RELEVANT APPARATUS
- B01J2219/00—Chemical, physical or physico-chemical processes in general; Their relevant apparatus
- B01J2219/00274—Sequential or parallel reactions; Apparatus and devices for combinatorial chemistry or for making arrays; Chemical library technology
- B01J2219/00277—Apparatus
- B01J2219/00279—Features relating to reactor vessels
- B01J2219/00306—Reactor vessels in a multiple arrangement
- B01J2219/00308—Reactor vessels in a multiple arrangement interchangeably mounted in racks or blocks
- B01J2219/0031—Reactor vessels in a multiple arrangement interchangeably mounted in racks or blocks the racks or blocks being mounted in stacked arrangements
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01J—CHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY; THEIR RELEVANT APPARATUS
- B01J2219/00—Chemical, physical or physico-chemical processes in general; Their relevant apparatus
- B01J2219/00274—Sequential or parallel reactions; Apparatus and devices for combinatorial chemistry or for making arrays; Chemical library technology
- B01J2219/00277—Apparatus
- B01J2219/00351—Means for dispensing and evacuation of reagents
- B01J2219/00364—Pipettes
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01J—CHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY; THEIR RELEVANT APPARATUS
- B01J2219/00—Chemical, physical or physico-chemical processes in general; Their relevant apparatus
- B01J2219/00274—Sequential or parallel reactions; Apparatus and devices for combinatorial chemistry or for making arrays; Chemical library technology
- B01J2219/00277—Apparatus
- B01J2219/00351—Means for dispensing and evacuation of reagents
- B01J2219/00389—Feeding through valves
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01J—CHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY; THEIR RELEVANT APPARATUS
- B01J2219/00—Chemical, physical or physico-chemical processes in general; Their relevant apparatus
- B01J2219/00274—Sequential or parallel reactions; Apparatus and devices for combinatorial chemistry or for making arrays; Chemical library technology
- B01J2219/00277—Apparatus
- B01J2219/00351—Means for dispensing and evacuation of reagents
- B01J2219/00414—Means for dispensing and evacuation of reagents using suction
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01J—CHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY; THEIR RELEVANT APPARATUS
- B01J2219/00—Chemical, physical or physico-chemical processes in general; Their relevant apparatus
- B01J2219/00274—Sequential or parallel reactions; Apparatus and devices for combinatorial chemistry or for making arrays; Chemical library technology
- B01J2219/00277—Apparatus
- B01J2219/00351—Means for dispensing and evacuation of reagents
- B01J2219/00423—Means for dispensing and evacuation of reagents using filtration, e.g. through porous frits
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01J—CHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY; THEIR RELEVANT APPARATUS
- B01J2219/00—Chemical, physical or physico-chemical processes in general; Their relevant apparatus
- B01J2219/00274—Sequential or parallel reactions; Apparatus and devices for combinatorial chemistry or for making arrays; Chemical library technology
- B01J2219/00277—Apparatus
- B01J2219/00497—Features relating to the solid phase supports
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- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01J—CHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY; THEIR RELEVANT APPARATUS
- B01J2219/00—Chemical, physical or physico-chemical processes in general; Their relevant apparatus
- B01J2219/00274—Sequential or parallel reactions; Apparatus and devices for combinatorial chemistry or for making arrays; Chemical library technology
- B01J2219/00583—Features relative to the processes being carried out
- B01J2219/00585—Parallel processes
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- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01J—CHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY; THEIR RELEVANT APPARATUS
- B01J2219/00—Chemical, physical or physico-chemical processes in general; Their relevant apparatus
- B01J2219/00274—Sequential or parallel reactions; Apparatus and devices for combinatorial chemistry or for making arrays; Chemical library technology
- B01J2219/00583—Features relative to the processes being carried out
- B01J2219/0059—Sequential processes
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01J—CHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY; THEIR RELEVANT APPARATUS
- B01J2219/00—Chemical, physical or physico-chemical processes in general; Their relevant apparatus
- B01J2219/00274—Sequential or parallel reactions; Apparatus and devices for combinatorial chemistry or for making arrays; Chemical library technology
- B01J2219/00583—Features relative to the processes being carried out
- B01J2219/00596—Solid-phase processes
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01J—CHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY; THEIR RELEVANT APPARATUS
- B01J2219/00—Chemical, physical or physico-chemical processes in general; Their relevant apparatus
- B01J2219/00274—Sequential or parallel reactions; Apparatus and devices for combinatorial chemistry or for making arrays; Chemical library technology
- B01J2219/0068—Means for controlling the apparatus of the process
- B01J2219/00686—Automatic
- B01J2219/00689—Automatic using computers
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01J—CHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY; THEIR RELEVANT APPARATUS
- B01J2219/00—Chemical, physical or physico-chemical processes in general; Their relevant apparatus
- B01J2219/00274—Sequential or parallel reactions; Apparatus and devices for combinatorial chemistry or for making arrays; Chemical library technology
- B01J2219/0068—Means for controlling the apparatus of the process
- B01J2219/00695—Synthesis control routines, e.g. using computer programs
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01J—CHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY; THEIR RELEVANT APPARATUS
- B01J2219/00—Chemical, physical or physico-chemical processes in general; Their relevant apparatus
- B01J2219/00274—Sequential or parallel reactions; Apparatus and devices for combinatorial chemistry or for making arrays; Chemical library technology
- B01J2219/00718—Type of compounds synthesised
- B01J2219/0072—Organic compounds
- B01J2219/00725—Peptides
-
- C—CHEMISTRY; METALLURGY
- C40—COMBINATORIAL TECHNOLOGY
- C40B—COMBINATORIAL CHEMISTRY; LIBRARIES, e.g. CHEMICAL LIBRARIES
- C40B40/00—Libraries per se, e.g. arrays, mixtures
- C40B40/04—Libraries containing only organic compounds
- C40B40/10—Libraries containing peptides or polypeptides, or derivatives thereof
-
- C—CHEMISTRY; METALLURGY
- C40—COMBINATORIAL TECHNOLOGY
- C40B—COMBINATORIAL CHEMISTRY; LIBRARIES, e.g. CHEMICAL LIBRARIES
- C40B60/00—Apparatus specially adapted for use in combinatorial chemistry or with libraries
- C40B60/14—Apparatus specially adapted for use in combinatorial chemistry or with libraries for creating libraries
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Analytical Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Biochemistry (AREA)
- Biophysics (AREA)
- General Health & Medical Sciences (AREA)
- Genetics & Genomics (AREA)
- Medicinal Chemistry (AREA)
- Molecular Biology (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Peptides Or Proteins (AREA)
- Saccharide Compounds (AREA)
- Physical Or Chemical Processes And Apparatus (AREA)
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
DE4005518A DE4005518A1 (en) | 1990-02-22 | 1990-02-22 | METHOD AND DEVICE FOR SIMULTANEOUS SYNTHESIS OF SEVERAL POLYPEPTIDES |
DE4005518 | 1990-02-22 |
Publications (2)
Publication Number | Publication Date |
---|---|
AU7240291A true AU7240291A (en) | 1991-09-18 |
AU642710B2 AU642710B2 (en) | 1993-10-28 |
Family
ID=6400688
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
AU72402/91A Ceased AU642710B2 (en) | 1990-02-22 | 1991-02-20 | Process and device for the simultaneous synthesis of several polypeptides |
Country Status (6)
Country | Link |
---|---|
EP (1) | EP0516672B1 (en) |
JP (1) | JPH05504147A (en) |
AU (1) | AU642710B2 (en) |
CA (1) | CA2076683A1 (en) |
DE (2) | DE4005518A1 (en) |
WO (1) | WO1991013084A1 (en) |
Families Citing this family (22)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
JP2787963B2 (en) * | 1991-08-24 | 1998-08-20 | 株式会社島津製作所 | Reaction tank |
JPH0720546B2 (en) * | 1991-08-26 | 1995-03-08 | 株式会社島津製作所 | Multi-item simultaneous chemical reactor |
US5324483B1 (en) * | 1992-10-08 | 1996-09-24 | Warner Lambert Co | Apparatus for multiple simultaneous synthesis |
US5702672A (en) * | 1992-10-08 | 1997-12-30 | Warner-Lambert Company | Apparatus and method for multiple simultaneous synthesis |
US5714127A (en) * | 1992-10-08 | 1998-02-03 | Warner-Lambert Company | System for multiple simultaneous synthesis |
US5565173A (en) * | 1992-10-08 | 1996-10-15 | Warner-Lambert Company | Apparatus and method for multiple simultaneous synthesis |
JPH06128286A (en) * | 1992-10-13 | 1994-05-10 | Shimadzu Corp | Automatic peptide synthesizer |
US5470703A (en) * | 1992-10-21 | 1995-11-28 | Shimadzu Corporation | Method for peptide C-terminal fragment sequence analysis and apparatus for collecting peptide fragment |
JPH06220084A (en) * | 1993-01-23 | 1994-08-09 | Shimadzu Corp | Peptide synthesizer |
US5472672A (en) * | 1993-10-22 | 1995-12-05 | The Board Of Trustees Of The Leland Stanford Junior University | Apparatus and method for polymer synthesis using arrays |
DE19602464B4 (en) * | 1996-01-24 | 2006-05-04 | Rapp, Wolfgang, Dr. | Device for the multiple, simultaneous and parallel synthesis of chemical compounds and for the discrete further treatment of aliquots |
EP0917493A1 (en) * | 1996-08-12 | 1999-05-26 | Monsanto Company | Solid phase organic synthesis device with pressure-regulated manifold |
US5792430A (en) * | 1996-08-12 | 1998-08-11 | Monsanto Company | Solid phase organic synthesis device with pressure-regulated manifold |
US5785927A (en) * | 1996-10-24 | 1998-07-28 | Eli Lilly And Company | Vessel handling system useful for combinatorial chemistry |
US6270730B1 (en) | 1998-06-16 | 2001-08-07 | Northwest Engineering Inc. | Multi-well rotary synthesizer |
DE10057195A1 (en) * | 2000-11-17 | 2002-05-23 | Robert Loesel | Reaction vessel, used for carrying out chemical reactions, comprises base formed by membrane having liquid permeability that can be controlled using pressures |
US6932943B1 (en) | 2001-01-26 | 2005-08-23 | Third Wave Technologies | Nucleic acid synthesizers |
US7435390B2 (en) | 2001-01-26 | 2008-10-14 | Third Wave Technologies, Inc. | Nucleic acid synthesizers |
US20050009022A1 (en) * | 2001-07-06 | 2005-01-13 | Weiner Michael P. | Method for isolation of independent, parallel chemical micro-reactions using a porous filter |
CN107056879A (en) * | 2017-03-08 | 2017-08-18 | 河南工程学院 | Multichannel Solid-phase synthesis peptides device |
CN108264536B (en) * | 2018-03-27 | 2023-08-08 | 润辉生物技术(威海)有限公司 | Continuous high-flux polypeptide synthesis device and application method thereof |
CN110590901A (en) * | 2019-10-11 | 2019-12-20 | 浙江昂拓莱司生物技术有限公司 | Method for quickly constructing trace peptide library and synthesis device thereof |
Family Cites Families (3)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
FR2582655B1 (en) * | 1985-06-03 | 1988-12-23 | Centre Nat Rech Scient | SOLID PHASE SEMI-AUTOMATIC PEPTIDE MULTI-SYNTHESIZER |
US4775629A (en) * | 1987-05-05 | 1988-10-04 | E. I. Du Pont De Nemours And Company | Apparatus for processing fluids |
DE3828576A1 (en) * | 1988-08-23 | 1990-03-08 | Boehringer Ingelheim Kg | METHOD AND DEVICE FOR THE FULLY AUTOMATIC SIMULTANEOUS SYNTHESIS OF SEVERAL POLYPEPTIDES |
-
1990
- 1990-02-22 DE DE4005518A patent/DE4005518A1/en not_active Withdrawn
-
1991
- 1991-02-20 JP JP3504203A patent/JPH05504147A/en active Pending
- 1991-02-20 WO PCT/EP1991/000318 patent/WO1991013084A1/en active IP Right Grant
- 1991-02-20 AU AU72402/91A patent/AU642710B2/en not_active Ceased
- 1991-02-20 EP EP91904242A patent/EP0516672B1/en not_active Expired - Lifetime
- 1991-02-20 CA CA002076683A patent/CA2076683A1/en not_active Abandoned
- 1991-02-20 DE DE59101618T patent/DE59101618D1/en not_active Expired - Lifetime
Also Published As
Publication number | Publication date |
---|---|
JPH05504147A (en) | 1993-07-01 |
AU642710B2 (en) | 1993-10-28 |
DE4005518A1 (en) | 1991-08-29 |
CA2076683A1 (en) | 1991-08-23 |
EP0516672A1 (en) | 1992-12-09 |
EP0516672B1 (en) | 1994-05-11 |
DE59101618D1 (en) | 1994-06-16 |
WO1991013084A1 (en) | 1991-09-05 |
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