AU7239287A - Anthelmintic acylhydrazones, method of use and compositions - Google Patents

Anthelmintic acylhydrazones, method of use and compositions

Info

Publication number
AU7239287A
AU7239287A AU72392/87A AU7239287A AU7239287A AU 7239287 A AU7239287 A AU 7239287A AU 72392/87 A AU72392/87 A AU 72392/87A AU 7239287 A AU7239287 A AU 7239287A AU 7239287 A AU7239287 A AU 7239287A
Authority
AU
Australia
Prior art keywords
acylhydrazones
anthelmintic
compositions
cestodes
trematodes
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Abandoned
Application number
AU72392/87A
Inventor
George A. Conder
Sylvester D. Folz
Douglas L. Rector
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Pharmacia and Upjohn Co
Original Assignee
Upjohn Co
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Upjohn Co filed Critical Upjohn Co
Publication of AU7239287A publication Critical patent/AU7239287A/en
Abandoned legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
    • C07D401/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
    • C07D401/12—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings linked by a chain containing hetero atoms as chain links
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P33/00—Antiparasitic agents
    • A61P33/10—Anthelmintics
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D209/00—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom
    • C07D209/02—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom condensed with one carbocyclic ring
    • C07D209/04—Indoles; Hydrogenated indoles
    • C07D209/10—Indoles; Hydrogenated indoles with substituted hydrocarbon radicals attached to carbon atoms of the hetero ring
    • C07D209/14—Radicals substituted by nitrogen atoms, not forming part of a nitro radical
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D307/00—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom
    • C07D307/77—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom ortho- or peri-condensed with carbocyclic rings or ring systems
    • C07D307/78—Benzo [b] furans; Hydrogenated benzo [b] furans
    • C07D307/79—Benzo [b] furans; Hydrogenated benzo [b] furans with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached to carbon atoms of the hetero ring
    • C07D307/81—Radicals substituted by nitrogen atoms not forming part of a nitro radical
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D311/00—Heterocyclic compounds containing six-membered rings having one oxygen atom as the only hetero atom, condensed with other rings
    • C07D311/02—Heterocyclic compounds containing six-membered rings having one oxygen atom as the only hetero atom, condensed with other rings ortho- or peri-condensed with carbocyclic rings or ring systems
    • C07D311/04—Benzo[b]pyrans, not hydrogenated in the carbocyclic ring
    • C07D311/06—Benzo[b]pyrans, not hydrogenated in the carbocyclic ring with oxygen or sulfur atoms directly attached in position 2
    • C07D311/08—Benzo[b]pyrans, not hydrogenated in the carbocyclic ring with oxygen or sulfur atoms directly attached in position 2 not hydrogenated in the hetero ring
    • C07D311/12—Benzo[b]pyrans, not hydrogenated in the carbocyclic ring with oxygen or sulfur atoms directly attached in position 2 not hydrogenated in the hetero ring substituted in position 3 and unsubstituted in position 7
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D333/00—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom
    • C07D333/50—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom condensed with carbocyclic rings or ring systems
    • C07D333/52—Benzo[b]thiophenes; Hydrogenated benzo[b]thiophenes
    • C07D333/54—Benzo[b]thiophenes; Hydrogenated benzo[b]thiophenes with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached to carbon atoms of the hetero ring
    • C07D333/58—Radicals substituted by nitrogen atoms

Landscapes

  • Organic Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Tropical Medicine & Parasitology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Indole Compounds (AREA)

Abstract

Process for killing internal parasites, especially nematodes, trematodes, and cestodes affecting warm blooded animals such as sheep, cattle, swine, goats, dogs, cats, horses and humans as well as poultry by administering an effective amount of a compound of formula (I). The compounds are readily prepared by conventional chemical reactions.
AU72392/87A 1986-04-07 1987-04-03 Anthelmintic acylhydrazones, method of use and compositions Abandoned AU7239287A (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US84903486A 1986-04-07 1986-04-07
US849034 1986-04-07

Publications (1)

Publication Number Publication Date
AU7239287A true AU7239287A (en) 1987-11-09

Family

ID=25304904

Family Applications (1)

Application Number Title Priority Date Filing Date
AU72392/87A Abandoned AU7239287A (en) 1986-04-07 1987-04-03 Anthelmintic acylhydrazones, method of use and compositions

Country Status (6)

Country Link
EP (1) EP0299973B1 (en)
JP (1) JPH01502585A (en)
AT (1) ATE77237T1 (en)
AU (1) AU7239287A (en)
DE (1) DE3779916T2 (en)
WO (1) WO1987006133A1 (en)

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
AU602140B2 (en) * 1986-04-07 1990-10-04 Upjohn Company, The Anthelmintic acylhydrazones, method of use and compositions

Families Citing this family (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5049561A (en) * 1987-07-31 1991-09-17 The Upjohn Company Anthelmintic acylhydrazones, method of use and compositions
JPH10338673A (en) * 1997-06-04 1998-12-22 Nippon Bayeragrochem Kk Isonicotinic acid hydrazide derivative and pest controlling agent
US7781480B2 (en) * 2007-03-27 2010-08-24 Vlife Sciences Technologies Pvt. Ltd. Indole derivatives and their metal conjugates and uses thereof
WO2012051708A1 (en) * 2010-10-21 2012-04-26 The University Of British Columbia Anti-bacterial pyruvate kinase modulator compounds, compositions, uses, and methods
EP3535242B1 (en) 2016-10-20 2024-01-24 B.G. Negev Technologies and Applications Ltd., at Ben-Gurion University Dna primase and gyrase inhibitors
CN107033063B (en) * 2017-06-20 2019-07-05 齐鲁工业大学 Preparation, structure and the purposes of 4-acetylbiphenyl hydrazone -4- indolecarboxaldehyde Schiff base
CN107043344B (en) * 2017-06-20 2019-07-05 齐鲁工业大学 Preparation, structure and the purposes of 4-acetylbiphenyl hydrazone-N- methyl -3- indolecarboxaldehyde Schiff base
CN115558485B (en) * 2022-09-28 2024-05-24 哈尔滨理工大学 Preparation method and application of fluorescent sensor for detecting phosphate radical

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US2775593A (en) * 1948-10-01 1956-12-25 Schenley Ind Inc Thiosemicarbazones of aldehydes and ketones of the heterocyclic series
US3882149A (en) * 1973-12-17 1975-05-06 American Cyanamid Co Substituted benzofuranyl ethylidene carbazic acid esters
WO1986005982A2 (en) * 1985-04-11 1986-10-23 Upjohn Co Anthelmintic quinolinyl acylhydrazones, method of use and compositions

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
AU602140B2 (en) * 1986-04-07 1990-10-04 Upjohn Company, The Anthelmintic acylhydrazones, method of use and compositions

Also Published As

Publication number Publication date
JPH01502585A (en) 1989-09-07
DE3779916T2 (en) 1993-02-04
ATE77237T1 (en) 1992-07-15
EP0299973B1 (en) 1992-06-17
DE3779916D1 (en) 1992-07-23
EP0299973A1 (en) 1989-01-25
WO1987006133A1 (en) 1987-10-22

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