AU7130101A - Enzyme-cleavable prodrug compounds - Google Patents
Enzyme-cleavable prodrug compoundsInfo
- Publication number
- AU7130101A AU7130101A AU7130101A AU7130101A AU7130101A AU 7130101 A AU7130101 A AU 7130101A AU 7130101 A AU7130101 A AU 7130101A AU 7130101 A AU7130101 A AU 7130101A AU 7130101 A AU7130101 A AU 7130101A
- Authority
- AU
- Australia
- Prior art keywords
- enzyme
- prodrug compounds
- cleavable prodrug
- cleavable
- compounds
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Pending
Links
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/50—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates
- A61K47/51—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent
- A61K47/62—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent the modifying agent being a protein, peptide or polyamino acid
- A61K47/65—Peptidic linkers, binders or spacers, e.g. peptidic enzyme-labile linkers
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- Animal Behavior & Ethology (AREA)
- General Chemical & Material Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Organic Chemistry (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Oncology (AREA)
- Epidemiology (AREA)
- Communicable Diseases (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Pain & Pain Management (AREA)
- Rheumatology (AREA)
- Medicinal Preparation (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Peptides Or Proteins (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Applications Claiming Priority (3)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US21188700P | 2000-06-14 | 2000-06-14 | |
US29044801P | 2001-05-11 | 2001-05-11 | |
PCT/US2001/018903 WO2001095945A2 (en) | 2000-06-14 | 2001-06-11 | Prodrug compounds cleavable by thimet oligopeptidase |
Publications (1)
Publication Number | Publication Date |
---|---|
AU7130101A true AU7130101A (en) | 2001-12-24 |
Family
ID=26906558
Family Applications (2)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
AU7130101A Pending AU7130101A (en) | 2000-06-14 | 2001-06-11 | Enzyme-cleavable prodrug compounds |
AU2001271301A Ceased AU2001271301B2 (en) | 2000-06-14 | 2001-06-11 | Prodrug compounds cleavable by thimet oligopeptidase |
Family Applications After (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
AU2001271301A Ceased AU2001271301B2 (en) | 2000-06-14 | 2001-06-11 | Prodrug compounds cleavable by thimet oligopeptidase |
Country Status (5)
Country | Link |
---|---|
EP (1) | EP1294405A2 (en) |
JP (1) | JP2004510703A (en) |
AU (2) | AU7130101A (en) |
CA (1) | CA2411660C (en) |
WO (1) | WO2001095945A2 (en) |
Families Citing this family (12)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
KR20030033007A (en) | 2001-05-31 | 2003-04-26 | 코울터 파머수티컬, 인코포레이티드 | Cytotoxins, prodrugs, linkers and stabilizers useful therefor |
DE60239679D1 (en) * | 2001-06-11 | 2011-05-19 | Medarex Inc | METHOD FOR MACHINING CD10-ACTIVATED PRODRUG COMPOUNDS |
FR2858936A1 (en) * | 2003-08-22 | 2005-02-25 | Diatos | New active compound precursor, useful as therapeutic or diagnostic agent or tracer, includes cleavable component that increases half-life in the circulation, attached through hydrophilic spacer |
TWI447124B (en) | 2006-12-01 | 2014-08-01 | Medarex Llc | Human antibodies that bind cd22 and uses thereof |
CL2007003622A1 (en) | 2006-12-13 | 2009-08-07 | Medarex Inc | Human anti-cd19 monoclonal antibody; composition comprising it; and tumor cell growth inhibition method. |
IN2009KN02404A (en) | 2006-12-14 | 2015-08-07 | Medarex Inc | |
DE102008007381A1 (en) * | 2008-02-01 | 2009-08-13 | Dritte Patentportfolio Beteiligungsgesellschaft Mbh & Co.Kg | Amidines and guanidines and their derivatives for the treatment of diseases |
US9662308B2 (en) | 2008-02-01 | 2017-05-30 | Dritte Patentportfolio Beteiligungsgesellschaft Mbh & Co. Kg | Orally bioavailable pentamidine prodrugs for the treatment of diseases |
WO2014147124A1 (en) | 2013-03-21 | 2014-09-25 | Sanofi-Aventis Deutschland Gmbh | Synthesis of hydantoin containing peptide products |
US10450343B2 (en) | 2013-03-21 | 2019-10-22 | Sanofi-Aventis Deutschland Gmbh | Synthesis of cyclic imide containing peptide products |
EP4267188A1 (en) | 2020-12-22 | 2023-11-01 | Cobiores NV | Compounds comprising a tetrapeptidic moiety |
WO2022167664A1 (en) | 2021-02-07 | 2022-08-11 | Cobiores Nv | Compounds comprising a tetrapeptidic moiety |
Family Cites Families (2)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
DE69535665T2 (en) * | 1994-08-19 | 2009-04-02 | La Region Wallonne | CONJUGATES CONTAIN AN ANTITUMORAL AGENT AND ITS USE |
IL143666A0 (en) * | 1998-12-11 | 2002-04-21 | Coulter Pharm Inc | Prodrug compounds and process for preparation thereof |
-
2001
- 2001-06-11 AU AU7130101A patent/AU7130101A/en active Pending
- 2001-06-11 EP EP01950291A patent/EP1294405A2/en not_active Withdrawn
- 2001-06-11 WO PCT/US2001/018903 patent/WO2001095945A2/en active Application Filing
- 2001-06-11 JP JP2002510122A patent/JP2004510703A/en active Pending
- 2001-06-11 CA CA2411660A patent/CA2411660C/en not_active Expired - Fee Related
- 2001-06-11 AU AU2001271301A patent/AU2001271301B2/en not_active Ceased
Also Published As
Publication number | Publication date |
---|---|
CA2411660C (en) | 2011-03-01 |
WO2001095945A3 (en) | 2002-08-15 |
AU2001271301B2 (en) | 2006-08-31 |
WO2001095945A2 (en) | 2001-12-20 |
CA2411660A1 (en) | 2001-12-20 |
EP1294405A2 (en) | 2003-03-26 |
JP2004510703A (en) | 2004-04-08 |
Similar Documents
Publication | Publication Date | Title |
---|---|---|
AU7552501A (en) | Tripeptide prodrug compounds | |
GB0107758D0 (en) | Anti-cancer compounds | |
AU6685301A (en) | Prodrug compounds with isoleucine | |
EP1349851A4 (en) | Compounds | |
AU7130101A (en) | Enzyme-cleavable prodrug compounds | |
AU2405002A (en) | Dehalogeno compounds | |
GB0027552D0 (en) | Anti-tumor compounds | |
GB0028105D0 (en) | Compounds | |
AU2002221812A1 (en) | Fap-activated anti-tumour prodrug | |
GB0007636D0 (en) | Anti-cancer compounds | |
GB0015117D0 (en) | Anti-cancer compounds | |
GB0027551D0 (en) | Anti-tumor compounds | |
GB0014642D0 (en) | Compounds | |
GB0006797D0 (en) | Compounds | |
GB0020503D0 (en) | Compounds | |
GB0018351D0 (en) | Compounds | |
GB0018306D0 (en) | Compounds | |
GB0015902D0 (en) | Compounds | |
GB0015863D0 (en) | Compounds | |
GB0003140D0 (en) | Compounds | |
GB0015852D0 (en) | Compounds | |
GB0014823D0 (en) | Compounds | |
GB0014652D0 (en) | Compounds | |
GB0023193D0 (en) | Compounds | |
GB0014641D0 (en) | Compounds |