US6265379B1
(en)
*
|
1999-10-13 |
2001-07-24 |
Allergan Sales, Inc. |
Method for treating otic disorders
|
US7838007B2
(en)
|
1999-12-07 |
2010-11-23 |
Allergan, Inc. |
Methods for treating mammary gland disorders
|
US7838008B2
(en)
*
|
1999-12-07 |
2010-11-23 |
Allergan, Inc. |
Methods for treating diverse cancers
|
US6821520B2
(en)
*
|
2000-02-15 |
2004-11-23 |
Allergan, Inc. |
Clostridial toxin therapy for Hashimoto's thyroiditis
|
US20040170665A1
(en)
*
|
2000-06-02 |
2004-09-02 |
Allergan, Inc. |
Intravitreal botulinum toxin implant
|
US20040033241A1
(en)
*
|
2000-06-02 |
2004-02-19 |
Allergan, Inc. |
Controlled release botulinum toxin system
|
US20040219619A1
(en)
*
|
2000-07-21 |
2004-11-04 |
Ester Fernandez-Salas |
Methods of identifying compounds that alter toxin persistence and/or protease activity
|
US6903187B1
(en)
*
|
2000-07-21 |
2005-06-07 |
Allergan, Inc. |
Leucine-based motif and clostridial neurotoxins
|
US7691983B2
(en)
|
2000-07-21 |
2010-04-06 |
Allergan, Inc. |
Chimera botulinum toxin type E
|
US7491799B2
(en)
*
|
2000-07-21 |
2009-02-17 |
Allergan, Inc. |
Modified botulinum neurotoxins
|
JP4707254B2
(en)
*
|
2001-04-24 |
2011-06-22 |
クミアイ化学工業株式会社 |
Granular composition and method for producing the same
|
US7115399B2
(en)
*
|
2001-07-31 |
2006-10-03 |
Allergan, Inc. |
Pinna reflex assay
|
US6984375B2
(en)
*
|
2001-08-03 |
2006-01-10 |
Allergan, Inc. |
Nuclei density and nuclei area methods for determining effects of a botulinum toxin on muscles
|
EP1443932B1
(en)
|
2001-11-15 |
2012-12-26 |
Micro Algae Corporation |
Pharmaceutical compositions containing 3,4-propinoperhydropurines and uses thereof for blocking neuronal transmission
|
WO2003071986A2
(en)
*
|
2002-02-22 |
2003-09-04 |
Control Delivery Systems, Inc. |
Method for treating otic disorders
|
US6688311B2
(en)
|
2002-03-14 |
2004-02-10 |
Allergan, Inc. |
Method for determining effect of a clostridial toxin upon a muscle
|
US7140371B2
(en)
*
|
2002-03-14 |
2006-11-28 |
Allergan, Inc. |
Surface topography method for determining effects of a botulinum toxin upon a muscle and for comparing botulinum toxins
|
US7589110B2
(en)
*
|
2002-09-06 |
2009-09-15 |
Durect Corporation |
Delivery of modulators of glutamate-mediated neurotransmission to the inner ear
|
US6656172B1
(en)
*
|
2002-09-27 |
2003-12-02 |
Medtronic, Inc. |
Method for treating severe tinnitus
|
US6969383B2
(en)
*
|
2002-09-27 |
2005-11-29 |
Medtronic, Inc. |
Method for treating severe tinnitus
|
KR20050061541A
(en)
*
|
2002-10-15 |
2005-06-22 |
알러간, 인코포레이티드 |
Botulinum toxin dental therapies and procedures
|
US20040086532A1
(en)
*
|
2002-11-05 |
2004-05-06 |
Allergan, Inc., |
Botulinum toxin formulations for oral administration
|
US7238357B2
(en)
*
|
2002-11-05 |
2007-07-03 |
Allergan, Inc. |
Methods for treating ulcers and gastroesophageal reflux disease
|
US8071550B2
(en)
*
|
2003-03-03 |
2011-12-06 |
Allergan, Inc. |
Methods for treating uterine disorders
|
AU2004216901B2
(en)
*
|
2003-03-06 |
2009-11-12 |
Botulinum Toxin Research Associates, Inc. |
Treatment of chronic chalazion and hordeolum with botulinum toxin
|
KR20050109969A
(en)
*
|
2003-03-06 |
2005-11-22 |
보툴리늄 톡신 리서치 어쏘시에이츠, 인크. |
Treatment of sinusitis related chronic facial pain and headache with botulinum toxin
|
WO2004093870A1
(en)
*
|
2003-03-20 |
2004-11-04 |
Pharmacia Corporation |
Treatment and prevention of otic disorders
|
US7390496B2
(en)
*
|
2003-04-25 |
2008-06-24 |
Allergan, Inc. |
Therapeutic treatments for repetitive hand washing
|
US7393537B2
(en)
*
|
2003-04-25 |
2008-07-01 |
Allergan, Inc. |
Botulinum toxin for treatment of obsessive compulsive finger biting disorder
|
US7393538B2
(en)
*
|
2003-04-25 |
2008-07-01 |
Ackerman Alan H |
Clostridial toxin treatment for dermatillomania
|
US7422753B2
(en)
*
|
2003-04-25 |
2008-09-09 |
Allergan, Inc. |
Methods for treating trichotillomania
|
US7396535B2
(en)
*
|
2003-04-25 |
2008-07-08 |
Ackerman Alan H |
Therapy for obsessive compulsive head banging
|
US6838434B2
(en)
*
|
2003-05-02 |
2005-01-04 |
Allergan, Inc. |
Methods for treating sinus headache
|
US20040226556A1
(en)
*
|
2003-05-13 |
2004-11-18 |
Deem Mark E. |
Apparatus for treating asthma using neurotoxin
|
US7220422B2
(en)
*
|
2003-05-20 |
2007-05-22 |
Allergan, Inc. |
Methods and compositions for treating eye disorders
|
US20040253274A1
(en)
*
|
2003-06-11 |
2004-12-16 |
Allergan, Inc. |
Use of a clostridial toxin to reduce appetite
|
US20050013850A1
(en)
*
|
2003-07-15 |
2005-01-20 |
Caers Jan K. |
Device to assist hyperhydrosis therapy
|
FR2857595B1
(en)
*
|
2003-07-18 |
2005-10-07 |
Sod Conseils Rech Applic |
USE OF BOTULINUM TOXIN FOR PREPARING A MEDICAMENT FOR PREVENTING OR TREATING AGONY-RELATED SOUND DISORDERS
|
US8609112B2
(en)
|
2003-10-29 |
2013-12-17 |
Allergan, Inc. |
Botulinum toxin treatments of depression
|
US8734810B2
(en)
|
2003-10-29 |
2014-05-27 |
Allergan, Inc. |
Botulinum toxin treatments of neurological and neuropsychiatric disorders
|
US8609113B2
(en)
|
2003-10-29 |
2013-12-17 |
Allergan, Inc. |
Botulinum toxin treatments of depression
|
US8617572B2
(en)
*
|
2003-10-29 |
2013-12-31 |
Allergan, Inc. |
Botulinum toxin treatments of depression
|
US7172764B2
(en)
*
|
2003-11-17 |
2007-02-06 |
Allergan, Inc. |
Rescue agents for treating botulinum toxin intoxications
|
US8048423B2
(en)
*
|
2003-12-09 |
2011-11-01 |
Allergan, Inc. |
Botulinum toxin therapy for skin disorders
|
US20050129677A1
(en)
*
|
2003-12-10 |
2005-06-16 |
Shengwen Li |
Lipid rafts and clostridial toxins
|
US20050148935A1
(en)
*
|
2003-12-29 |
2005-07-07 |
Rozalina Dimitrova |
Botulinum toxin injection guide
|
US7270287B2
(en)
*
|
2004-01-06 |
2007-09-18 |
Allergan, Inc. |
Botulinum toxin treatment for kinesia
|
US6974579B2
(en)
*
|
2004-01-08 |
2005-12-13 |
Allergan, Inc. |
Methods for treating vascular disorders
|
US20060063802A1
(en)
*
|
2004-03-29 |
2006-03-23 |
Matthieu Guitton |
Methods for the treatment of tinnitus induced by cochlear excitotoxicity
|
US8268866B2
(en)
*
|
2004-03-29 |
2012-09-18 |
Matthieu Guitton |
Methods for the treatment of tinnitus induced by cochlear excitotoxicity
|
US9072662B2
(en)
|
2004-03-29 |
2015-07-07 |
Auris Medical Ag |
Methods for the treatment of tinnitus induced by cochlear excitotoxicity
|
WO2005102345A1
(en)
*
|
2004-03-30 |
2005-11-03 |
Alcon, Inc. |
Use of rho kinase inhibitors in the treatment of hearing loss, tinnitus and improving body balance
|
CN1997373B
(en)
*
|
2004-05-07 |
2010-12-22 |
菲特托克斯有限公司 |
Phycotoxins and uses thereof
|
AU2005244096B2
(en)
*
|
2004-05-07 |
2011-03-17 |
Algenis Spa |
Transdermal administration of phycotoxins
|
US7514088B2
(en)
*
|
2005-03-15 |
2009-04-07 |
Allergan, Inc. |
Multivalent Clostridial toxin derivatives and methods of their use
|
US7811584B2
(en)
*
|
2004-06-30 |
2010-10-12 |
Allergan, Inc. |
Multivalent clostridial toxins
|
US20060024794A1
(en)
*
|
2004-07-30 |
2006-02-02 |
Shengwen Li |
Novel methods for production of di-chain botulinum toxin
|
WO2006013370A1
(en)
|
2004-08-04 |
2006-02-09 |
Ipsen Limited |
Pharmaceutical composition containing botulinum neurotoxin a2
|
TR201708749T4
(en)
*
|
2004-08-04 |
2018-03-21 |
Ipsen Biopharm Ltd |
PHARMACEUTICAL COMPOSITION CONTAINING BOTULINUM NEUROTOXIN A2
|
EP1982996A1
(en)
|
2004-09-01 |
2008-10-22 |
Allergan, Inc. |
Degradable clostridial toxins
|
US7429386B2
(en)
*
|
2004-09-03 |
2008-09-30 |
Allergan, Inc. |
Stretch mark treatment
|
US7179474B2
(en)
*
|
2004-09-03 |
2007-02-20 |
Allergan, Inc. |
Methods for treating a buttock deformity
|
US20060073208A1
(en)
|
2004-10-01 |
2006-04-06 |
Allergan, Inc. |
Cosmetic neurotoxin compositions and methods
|
KR20070116710A
(en)
|
2005-03-03 |
2007-12-11 |
알러간, 인코포레이티드 |
Animal product free system and process for purifying a botulinum toxin
|
AU2006225116B2
(en)
|
2005-03-15 |
2012-04-19 |
Allergan, Inc. |
Modified Clostridial toxins with altered targeting capabilities for Clostridial toxin target cells
|
US7419675B2
(en)
*
|
2005-05-26 |
2008-09-02 |
Allergan, Inc. |
Method for treating peritoneal adhesions
|
US8105611B2
(en)
*
|
2005-06-17 |
2012-01-31 |
Allergan, Inc. |
Treatment of autoimmune disorder with a neurotoxin
|
US10052465B2
(en)
|
2005-07-22 |
2018-08-21 |
The Foundry, Llc |
Methods and systems for toxin delivery to the nasal cavity
|
JP5826450B2
(en)
*
|
2005-07-22 |
2015-12-02 |
ザ ファウンドリー, エルエルシー |
Systems and methods for delivery of therapeutic agents
|
US7655243B2
(en)
|
2005-07-22 |
2010-02-02 |
The Foundry, Llc |
Methods and systems for toxin delivery to the nasal cavity
|
US7910116B2
(en)
*
|
2005-08-24 |
2011-03-22 |
Allergan, Inc. |
Use of a botulinum toxin to improve gastric emptying and/or to treat GERD
|
CU20080044A7
(en)
*
|
2005-09-28 |
2011-04-26 |
|
Pharmaceutical compositions for the treatment of disorders of the inner ear.
|
US7794386B2
(en)
|
2006-03-15 |
2010-09-14 |
Allergan, Inc. |
Methods for facilitating weight loss
|
US7811586B2
(en)
*
|
2006-05-02 |
2010-10-12 |
Allergan, Inc. |
Methods for alleviating testicular pain
|
US20080092910A1
(en)
*
|
2006-10-18 |
2008-04-24 |
Allergan, Inc. |
Apparatus and method for treating obesity using neurotoxins in conjunction with bariatric procedures
|
US20080113051A1
(en)
*
|
2006-11-13 |
2008-05-15 |
Allergan, Inc. |
Methods for alleviating tattoo pain
|
EP2117584B1
(en)
*
|
2007-02-15 |
2013-10-09 |
Allergan, Inc. |
Use of botulinum toxin and enzymes for treating bladder disorders
|
US8483831B1
(en)
|
2008-02-15 |
2013-07-09 |
Holaira, Inc. |
System and method for bronchial dilation
|
US8470337B2
(en)
*
|
2008-03-13 |
2013-06-25 |
Allergan, Inc. |
Therapeutic treatments using botulinum neurotoxin
|
US8617571B2
(en)
|
2008-04-03 |
2013-12-31 |
Allergan, Inc. |
Suture line administration technique using botulinum toxin
|
EP2529686B1
(en)
|
2008-05-09 |
2015-10-14 |
Holaira, Inc. |
System for treating a bronchial tree
|
US20100028385A1
(en)
*
|
2008-08-04 |
2010-02-04 |
Allergan, Inc. |
Treatment of excess cerumen secretion
|
WO2011049954A2
(en)
*
|
2009-10-21 |
2011-04-28 |
Otonomy, Inc. |
Compositions comprising wnt modulators or neurotoxins for the treatment of otic disorders
|
US9649153B2
(en)
|
2009-10-27 |
2017-05-16 |
Holaira, Inc. |
Delivery devices with coolable energy emitting assemblies
|
CA2780608C
(en)
|
2009-11-11 |
2019-02-26 |
Innovative Pulmonary Solutions, Inc. |
Systems, apparatuses, and methods for treating tissue and controlling stenosis
|
US8911439B2
(en)
|
2009-11-11 |
2014-12-16 |
Holaira, Inc. |
Non-invasive and minimally invasive denervation methods and systems for performing the same
|
US20120195878A1
(en)
|
2011-01-28 |
2012-08-02 |
Allergan, Inc. |
Protocol for the administration of botulinum toxins
|
US20120244188A1
(en)
*
|
2011-03-25 |
2012-09-27 |
Allergan, Inc. |
Treatment of Sensory Disturbance Disorders
|
EP2729163A1
(en)
|
2011-07-08 |
2014-05-14 |
Allergan, Inc. |
Method for treatment of autonomic nervous system disorders
|
US8992941B2
(en)
|
2011-07-08 |
2015-03-31 |
Allergan, Inc. |
Method for treatment of esophageal spasm
|
KR20140054055A
(en)
|
2011-07-14 |
2014-05-08 |
알러간, 인코포레이티드 |
Methods for treatment of incontinence associated with sexual activity
|
MX2014000612A
(en)
|
2011-07-20 |
2014-02-27 |
Allergan Inc |
Botulinum toxins for use in a method for treatment of adipose deposits.
|
ES2759478T3
(en)
|
2012-03-12 |
2020-05-11 |
William J Binder |
Treatment of migraine headaches with presynaptic neurotoxin
|
US8722060B2
(en)
*
|
2012-05-23 |
2014-05-13 |
William J. Binder |
Method of treating vertigo
|
EP2649985A1
(en)
|
2012-04-13 |
2013-10-16 |
Lipotec, S.A. |
Compounds which inhibit neuronal exocytosis (III)
|
ES2660901T3
(en)
|
2012-04-13 |
2018-03-26 |
Lubrizol Advanced Materials, Inc. |
Compounds that inhibit neuronal exocytosis (II)
|
EP2649983A1
(en)
|
2012-04-13 |
2013-10-16 |
Lipotec, S.A. |
Compounds which inhibit neuronal exocytosis (II)
|
EP2649984A1
(en)
|
2012-04-13 |
2013-10-16 |
Lipotec, S.A. |
Compounds which inhibit neuronal exocytosis
|
US9005628B2
(en)
|
2012-10-04 |
2015-04-14 |
Dublin City University |
Biotherapy for pain
|
US9398933B2
(en)
|
2012-12-27 |
2016-07-26 |
Holaira, Inc. |
Methods for improving drug efficacy including a combination of drug administration and nerve modulation
|
GB201312317D0
(en)
|
2013-07-09 |
2013-08-21 |
Syntaxin Ltd |
Cationic neurotoxins
|
US10149893B2
(en)
|
2013-09-24 |
2018-12-11 |
Allergan, Inc. |
Methods for modifying progression of osteoarthritis
|
US9480731B2
(en)
|
2013-12-12 |
2016-11-01 |
Medy-Tox, Inc. |
Long lasting effect of new botulinum toxin formulations
|
US9216210B2
(en)
|
2013-12-23 |
2015-12-22 |
Dublin City University |
Multiprotease therapeutics for chronic pain
|
HUE053935T2
(en)
|
2015-01-09 |
2021-08-30 |
Ipsen Bioinnovation Ltd |
Cationic neurotoxins
|
GB201517450D0
(en)
|
2015-10-02 |
2015-11-18 |
Ipsen Biopharm Ltd |
Method
|
GB201607901D0
(en)
|
2016-05-05 |
2016-06-22 |
Ipsen Biopharm Ltd |
Chimeric neurotoxins
|
EP3263710A1
(en)
|
2016-07-01 |
2018-01-03 |
Ipsen Biopharm Limited |
Production of activated clostridial neurotoxins
|
WO2018038301A1
(en)
|
2016-08-26 |
2018-03-01 |
Hugel Inc. |
Stabilized liquid formulation of botulinum toxin and preparation method thereof
|
EP3519430A1
(en)
|
2016-09-29 |
2019-08-07 |
Ipsen Biopharm Limited |
Hybrid neurotoxins
|
WO2019068888A1
(en)
|
2017-10-06 |
2019-04-11 |
Ranoux Daniele |
Use of botulinum toxin for the treatment of subjective tinnitus
|
EP3470054B1
(en)
|
2017-10-11 |
2023-09-20 |
Hugel Inc. |
Microstructure formulation techniques for botulinum toxin
|
US10792400B2
(en)
|
2017-10-12 |
2020-10-06 |
Hugel Inc. |
Microstructure formulation techniques for botulinum toxin
|
US10525111B2
(en)
|
2017-10-12 |
2020-01-07 |
Hugel, Inc. |
Microstructure formulation techniques for botulinum toxin
|
JP7186228B2
(en)
|
2018-02-26 |
2022-12-08 |
イプセン バイオファーム リミテッド |
Use of ultrasound to guide injection of non-cytotoxic proteases
|
LT3660509T
(en)
|
2018-11-29 |
2022-05-10 |
Hugel Inc. |
A cell-based method for determining an activity of botulinum toxin
|
GB202103372D0
(en)
|
2021-03-11 |
2021-04-28 |
Ipsen Biopharm Ltd |
Modified clostridial neurotoxins
|