AU706955B2 - 7-O-methoxymethyl paclitaxel - Google Patents

7-O-methoxymethyl paclitaxel Download PDF

Info

Publication number
AU706955B2
AU706955B2 AU31240/97A AU3124097A AU706955B2 AU 706955 B2 AU706955 B2 AU 706955B2 AU 31240/97 A AU31240/97 A AU 31240/97A AU 3124097 A AU3124097 A AU 3124097A AU 706955 B2 AU706955 B2 AU 706955B2
Authority
AU
Australia
Prior art keywords
compound
paclitaxel
methoxymethyl
ethyl acetate
mmol
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Ceased
Application number
AU31240/97A
Other languages
English (en)
Other versions
AU3124097A (en
Inventor
Mark D. Wittman
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Bristol Myers Squibb Co
Original Assignee
Bristol Myers Squibb Co
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Bristol Myers Squibb Co filed Critical Bristol Myers Squibb Co
Publication of AU3124097A publication Critical patent/AU3124097A/en
Application granted granted Critical
Publication of AU706955B2 publication Critical patent/AU706955B2/en
Anticipated expiration legal-status Critical
Ceased legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D305/00—Heterocyclic compounds containing four-membered rings having one oxygen atom as the only ring hetero atoms
    • C07D305/14—Heterocyclic compounds containing four-membered rings having one oxygen atom as the only ring hetero atoms condensed with carbocyclic rings or ring systems
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Epoxy Compounds (AREA)
AU31240/97A 1996-05-16 1997-05-08 7-O-methoxymethyl paclitaxel Ceased AU706955B2 (en)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US1791996P 1996-05-16 1996-05-16
US60/017919 1996-05-16
PCT/US1997/008079 WO1997042948A1 (en) 1996-05-16 1997-05-08 7-o-methoxymethyl paclitaxel

Publications (2)

Publication Number Publication Date
AU3124097A AU3124097A (en) 1997-12-05
AU706955B2 true AU706955B2 (en) 1999-07-01

Family

ID=21785279

Family Applications (1)

Application Number Title Priority Date Filing Date
AU31240/97A Ceased AU706955B2 (en) 1996-05-16 1997-05-08 7-O-methoxymethyl paclitaxel

Country Status (5)

Country Link
EP (1) EP0906095A1 (ja)
JP (1) JP2000510148A (ja)
AU (1) AU706955B2 (ja)
CA (1) CA2253443A1 (ja)
WO (1) WO1997042948A1 (ja)

Citations (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4960790A (en) * 1989-03-09 1990-10-02 University Of Kansas Derivatives of taxol, pharmaceutical compositions thereof and methods for the preparation thereof

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5646176A (en) * 1992-12-24 1997-07-08 Bristol-Myers Squibb Company Phosphonooxymethyl ethers of taxane derivatives
ATE171170T1 (de) * 1994-06-28 1998-10-15 Upjohn Co 7-äther-taxol ähnliche verbindungen antineoplastische verwendung und diese enthaltende pharmazeutische zusammenstellungen

Patent Citations (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4960790A (en) * 1989-03-09 1990-10-02 University Of Kansas Derivatives of taxol, pharmaceutical compositions thereof and methods for the preparation thereof

Non-Patent Citations (1)

* Cited by examiner, † Cited by third party
Title
DIGENIS ET AL., DRUG LATENTIATION, HANDBOOK OF PHARMACOLOGY, OCTOBER 1975, VOL.28, PP.86-112 *

Also Published As

Publication number Publication date
EP0906095A1 (en) 1999-04-07
WO1997042948A1 (en) 1997-11-20
EP0906095A4 (ja) 1999-05-12
AU3124097A (en) 1997-12-05
JP2000510148A (ja) 2000-08-08
CA2253443A1 (en) 1997-11-20

Similar Documents

Publication Publication Date Title
EP0960107B1 (en) 6-thio-substituted paclitaxels
AU722082B2 (en) 6-halo-or nitrate-substituted paclitaxels
WO1998008833A1 (en) Sulfenamide taxane derivatives
AU706155B2 (en) 7-deoxy-6-substituted paclitaxels
US5840929A (en) C4 methoxy ether derivatives of paclitaxel
US5773464A (en) C-10 epoxy taxanes
EP0856512A2 (en) 1-deoxy paclitaxels, method of preparation and pharmaceutical use
AU706955B2 (en) 7-O-methoxymethyl paclitaxel
CA2328771A1 (en) 2-aroyl-4-acyl paclitaxel (taxol) analogs
EP1263749B1 (en) Taxane anticancer agents
AU724591B2 (en) 7-methylthiooxomethyl and 7-methylthiodioxomethyl paclitaxels
AU2001245582A1 (en) Taxane anticancer agents
WO1998047360A1 (en) 7-sulfur substituted paclitaxels
WO1999032109A1 (en) 7-deoxy-6-nitrogen substituted paclitaxels
WO1998000419A1 (en) Ortho-ester analogs of paclitaxel
KR20030049023A (ko) 방사선 감작제용 파클리탁셀 유도체

Legal Events

Date Code Title Description
MK14 Patent ceased section 143(a) (annual fees not paid) or expired