AU6998394A - Arylidene-4-oxo-2-thioxo-3-thiazolidine carboxylic aids, method of preparing them and drugs containing such compounds - Google Patents

Arylidene-4-oxo-2-thioxo-3-thiazolidine carboxylic aids, method of preparing them and drugs containing such compounds

Info

Publication number
AU6998394A
AU6998394A AU69983/94A AU6998394A AU6998394A AU 6998394 A AU6998394 A AU 6998394A AU 69983/94 A AU69983/94 A AU 69983/94A AU 6998394 A AU6998394 A AU 6998394A AU 6998394 A AU6998394 A AU 6998394A
Authority
AU
Australia
Prior art keywords
arylidene
thioxo
oxo
preparing
compounds
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Abandoned
Application number
AU69983/94A
Inventor
Rudolf Reiter
Edgar Voss
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Roche Diagnostics GmbH
Original Assignee
Boehringer Mannheim GmbH
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Boehringer Mannheim GmbH filed Critical Boehringer Mannheim GmbH
Publication of AU6998394A publication Critical patent/AU6998394A/en
Abandoned legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D277/00—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings
    • C07D277/02—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings not condensed with other rings
    • C07D277/20—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D417/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00
    • C07D417/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings
    • C07D417/06—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings linked by a carbon chain containing only aliphatic carbon atoms

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Thiazole And Isothizaole Compounds (AREA)
AU69983/94A 1993-06-04 1994-05-28 Arylidene-4-oxo-2-thioxo-3-thiazolidine carboxylic aids, method of preparing them and drugs containing such compounds Abandoned AU6998394A (en)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
DE4318550 1993-06-04
DE19934318550 DE4318550A1 (en) 1993-06-04 1993-06-04 Arylidene-4-oxo-2-thioxo-3-thiazolidinecarboxylic acids, process for their preparation and pharmaceutical compositions containing them
PCT/EP1994/001749 WO1994029287A1 (en) 1993-06-04 1994-05-28 Arylidene-4-oxo-2-thioxo-3-thiazolidine carboxylic aids, method of preparing them and drugs containing such compounds

Publications (1)

Publication Number Publication Date
AU6998394A true AU6998394A (en) 1995-01-03

Family

ID=6489611

Family Applications (1)

Application Number Title Priority Date Filing Date
AU69983/94A Abandoned AU6998394A (en) 1993-06-04 1994-05-28 Arylidene-4-oxo-2-thioxo-3-thiazolidine carboxylic aids, method of preparing them and drugs containing such compounds

Country Status (3)

Country Link
AU (1) AU6998394A (en)
DE (1) DE4318550A1 (en)
WO (1) WO1994029287A1 (en)

Families Citing this family (35)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5914332A (en) * 1995-12-13 1999-06-22 Abbott Laboratories Retroviral protease inhibiting compounds
IL125974A0 (en) * 1996-03-07 1999-04-11 American Home Prod 2-thioxotetrahydropyrimidin-4-one derivatives
WO2000018747A1 (en) * 1998-09-30 2000-04-06 Roche Diagnostics Gmbh Rhodanine carboxylic acid derivatives for the treatment and prevention of metabolic bone disorders
JP2003502320A (en) * 1999-06-10 2003-01-21 ワーナー−ランバート・カンパニー Rhodanin derivatives for use in a method of inhibiting amyloid protein aggregation and imaging amyloid deposits
US6506755B2 (en) * 2000-02-03 2003-01-14 Hoffmann-La Roche Inc. Thiazolidinecarboxyl acids
GB0021421D0 (en) 2000-08-31 2000-10-18 Oxford Glycosciences Uk Ltd Compounds
GB0021419D0 (en) * 2000-08-31 2000-10-18 Oxford Glycosciences Uk Ltd Compounds
WO2003070238A1 (en) * 2002-02-23 2003-08-28 Oxford Glycosciences (Uk) Ltd Thiazolidine antifungal agents
US20060014812A1 (en) * 2004-07-14 2006-01-19 Player Mark R Use of estrogen related receptor-modulating aryl ethers
JP2007045946A (en) * 2005-08-10 2007-02-22 Shipro Kasei Kaisha Ltd Organic pigment using thiazolidine derivative
WO2009067697A1 (en) * 2007-11-21 2009-05-28 Regents Of The University Of Minnesota Therapeutic compounds
MX2010012626A (en) 2008-05-20 2011-02-22 Merck Sharp & Dohme Efficient production of heterologous proteins using mannosyl transferase inhibitors.
WO2013010218A1 (en) * 2011-07-15 2013-01-24 Freie Universität Berlin Inhibition of clathrin
EP2797597B1 (en) 2011-12-28 2020-02-26 Global Blood Therapeutics, Inc. Substituted heteroaryl aldehyde compounds and methods for their use in increasing tissue oxygenation
PE20221914A1 (en) 2011-12-28 2022-12-23 Global Blood Therapeutics Inc SUBSTITUTE BENZALDEHYDE COMPOUNDS AND METHODS FOR THEIR USE IN INCREASING TISSUE OXYGENATION
KR101971385B1 (en) 2013-03-15 2019-04-22 글로벌 블러드 테라퓨틱스, 인크. Compounds and uses thereof for the modulation of hemoglobin
AU2014237330A1 (en) 2013-03-15 2015-09-17 Global Blood Therapeutics, Inc. Compounds and uses thereof for the modulation of hemoglobin
US8952171B2 (en) 2013-03-15 2015-02-10 Global Blood Therapeutics, Inc. Compounds and uses thereof for the modulation of hemoglobin
US10266551B2 (en) 2013-03-15 2019-04-23 Global Blood Therapeutics, Inc. Compounds and uses thereof for the modulation of hemoglobin
US9802900B2 (en) 2013-03-15 2017-10-31 Global Blood Therapeutics, Inc. Bicyclic heteroaryl compounds and uses thereof for the modulation of hemoglobin
US9458139B2 (en) 2013-03-15 2016-10-04 Global Blood Therapeutics, Inc. Compounds and uses thereof for the modulation of hemoglobin
CN112500338A (en) 2013-03-15 2021-03-16 全球血液疗法股份有限公司 Compounds and their use for modulating hemoglobin
US10100043B2 (en) 2013-03-15 2018-10-16 Global Blood Therapeutics, Inc. Substituted aldehyde compounds and methods for their use in increasing tissue oxygenation
US9604999B2 (en) 2013-03-15 2017-03-28 Global Blood Therapeutics, Inc. Compounds and uses thereof for the modulation of hemoglobin
US9422279B2 (en) 2013-03-15 2016-08-23 Global Blood Therapeutics, Inc. Compounds and uses thereof for the modulation of hemoglobin
US20140274961A1 (en) 2013-03-15 2014-09-18 Global Blood Therapeutics, Inc. Compounds and uses thereof for the modulation of hemoglobin
EA201992707A1 (en) 2013-11-18 2020-06-30 Глобал Блад Терапьютикс, Инк. COMPOUNDS AND THEIR APPLICATIONS FOR HEMOGLOBIN MODULATION
AU2015214182B2 (en) 2014-02-07 2020-04-30 Global Blood Therapeutics, Inc. Crystalline polymorphs of the free base of 2-hydroxy-6-((2-(1-isopropyl-1H-pyrazol-5-yl)pyridin-3-yl)methoxy)benzaldehyde
EP3221299A1 (en) 2014-11-21 2017-09-27 BSIM2 Biomolecular Simulations Lda. 2-thioxothiazolidin-4-one derivatives active as transthyretin ligands and uses thereof
MA41841A (en) 2015-03-30 2018-02-06 Global Blood Therapeutics Inc ALDEHYDE COMPOUNDS FOR THE TREATMENT OF PULMONARY FIBROSIS, HYPOXIA, AND AUTOIMMUNE AND CONNECTIVE TISSUE DISEASES
MA43373A (en) 2015-12-04 2018-10-10 Global Blood Therapeutics Inc DOSAGE REGIMES FOR 2-HYDROXY-6 - ((2- (1-ISOPROPYL-1H-PYRAZOL-5-YL) PYRIDIN-3-YL) METHOXY) BENZALDEHYDE
TWI663160B (en) 2016-05-12 2019-06-21 全球血液治療公司 Process for synthesizing 2-hydroxy-6-((2-(1-isopropyl-1h-pyrazol-5-yl)-pyridin-3-yl)methoxy)benzaldehyde
TW202332423A (en) 2016-10-12 2023-08-16 美商全球血液治療公司 Tablets comprising 2-hydroxy-6-((2-(1-isopropyl-1h-pyrazol-5-yl)pyridin-3-yl)methoxy)benzaldehyde
WO2020046020A1 (en) * 2018-08-30 2020-03-05 서울대학교산학협력단 Inhibitory material against human body-derived nicotinamide adenine dinucleotide phosphate-dependent steroid dehydrogenase-like, and anticancer agent comprising same as effective ingredient or pharmaceutical composition comprising same as effective ingredient for treatment of hyperlipidemia
WO2020072377A1 (en) 2018-10-01 2020-04-09 Global Blood Therapeutics, Inc. Modulators of hemoglobin for the treatment of sickle cell disease

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
AT312602B (en) * 1971-04-13 1974-01-10 Boehringer Sohn Ingelheim Process for the preparation of new 3-carboxyalkyl-azolidinonmethylhydrazides and their salts
JPS5740478A (en) * 1980-08-22 1982-03-06 Ono Pharmaceut Co Ltd Rhodanine derivative, its preparation and aldose reductase inhibitor containing rhodanine derivative
KR870006897A (en) * 1986-01-07 1987-08-13 모리오까 시게오 Heterocyclic Compounds, Methods of Making the Same, and Pharmaceutical Compositions Containing the Same
GB8721302D0 (en) * 1987-09-10 1987-10-14 London King S College Substrates for assay of enzymes
JPH01172836A (en) * 1987-12-26 1989-07-07 Mita Ind Co Ltd Charge generating material and its production

Also Published As

Publication number Publication date
DE4318550A1 (en) 1994-12-08
WO1994029287A1 (en) 1994-12-22

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