AU6968287A - Cyclophosphazene compounds - Google Patents
Cyclophosphazene compoundsInfo
- Publication number
- AU6968287A AU6968287A AU69682/87A AU6968287A AU6968287A AU 6968287 A AU6968287 A AU 6968287A AU 69682/87 A AU69682/87 A AU 69682/87A AU 6968287 A AU6968287 A AU 6968287A AU 6968287 A AU6968287 A AU 6968287A
- Authority
- AU
- Australia
- Prior art keywords
- substituted
- radicals
- radical
- alkyl
- formula
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Abandoned
Links
- 150000001875 compounds Chemical class 0.000 title abstract 5
- -1 1-aziridinyl radical Chemical class 0.000 abstract 14
- 125000005843 halogen group Chemical group 0.000 abstract 4
- 150000003254 radicals Chemical class 0.000 abstract 4
- 238000006467 substitution reaction Methods 0.000 abstract 4
- 125000004450 alkenylene group Chemical group 0.000 abstract 2
- 125000000217 alkyl group Chemical group 0.000 abstract 2
- 125000002947 alkylene group Chemical group 0.000 abstract 2
- 125000004419 alkynylene group Chemical group 0.000 abstract 2
- 150000005840 aryl radicals Chemical class 0.000 abstract 2
- 125000004435 hydrogen atom Chemical group [H]* 0.000 abstract 2
- 125000003107 substituted aryl group Chemical group 0.000 abstract 2
- NOWKCMXCCJGMRR-UHFFFAOYSA-N Aziridine Chemical compound C1CN1 NOWKCMXCCJGMRR-UHFFFAOYSA-N 0.000 abstract 1
- 108091008663 GR-A Proteins 0.000 abstract 1
- 238000000034 method Methods 0.000 abstract 1
- 229920000768 polyamine Polymers 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07F—ACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
- C07F9/00—Compounds containing elements of Groups 5 or 15 of the Periodic Table
- C07F9/02—Phosphorus compounds
- C07F9/547—Heterocyclic compounds, e.g. containing phosphorus as a ring hetero atom
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07F—ACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
- C07F9/00—Compounds containing elements of Groups 5 or 15 of the Periodic Table
- C07F9/02—Phosphorus compounds
- C07F9/547—Heterocyclic compounds, e.g. containing phosphorus as a ring hetero atom
- C07F9/6564—Heterocyclic compounds, e.g. containing phosphorus as a ring hetero atom having phosphorus atoms, with or without nitrogen, oxygen, sulfur, selenium or tellurium atoms, as ring hetero atoms
- C07F9/6581—Heterocyclic compounds, e.g. containing phosphorus as a ring hetero atom having phosphorus atoms, with or without nitrogen, oxygen, sulfur, selenium or tellurium atoms, as ring hetero atoms having phosphorus and nitrogen atoms with or without oxygen or sulfur atoms, as ring hetero atoms
- C07F9/65812—Cyclic phosphazenes [P=N-]n, n>=3
- C07F9/65815—Cyclic phosphazenes [P=N-]n, n>=3 n = 3
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
Landscapes
- Chemical & Material Sciences (AREA)
- Health & Medical Sciences (AREA)
- Organic Chemistry (AREA)
- General Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Veterinary Medicine (AREA)
- Pharmacology & Pharmacy (AREA)
- General Chemical & Material Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Public Health (AREA)
- Medicinal Chemistry (AREA)
- Biochemistry (AREA)
- Molecular Biology (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Immunology (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Lubricants (AREA)
- Polymers With Sulfur, Phosphorus Or Metals In The Main Chain (AREA)
Abstract
1. Claims for the Contracting States : AT, BE, CH, DE, FR, GB, IT, LI, LU, NL, SE Compounds having the formula I : see diagramm : EP0240392,P18,F1 in which : Az is a 1-aziridinyl radical, substituted or non-substituted, the substitution consisting of 1 to 4 C1 to C3 alkyl or alkoxy radicals, A, B and C, independently of one another, can represent an alkylene or alkenylene or alkynylene chain which may be straight or branched, substituted or non-substituted, and can be interrupted by one or more divalent radicals -NR3 -, -S- or -O-, and R1 , R2 and R3 , independently of one another, can represent a hydrogen atom or a substituted or non-substituted alkyl radical or a substituted or non-substituted alkenyl radical or a substituted or non-substituted alkynyl radical or a substituted or non-substituted aryl radical, and the substitutions of the -A-, -B- and -C- chains and the radicals R1 , R2 and R3 are chosen from among one or more halogen atoms or imino, amino or aryl radicals, non-substituted or substituted by one or more halogen atoms or C1 to C3 alkyl radicals. 1. Claims for the Contracting States : ES, GR A method of preparing a compound having the formula I : see diagramm : EP0240392,P20,F1 in which : Az is a 1-aziridinyl radical, substituted or non-substituted, the substitution consisting of 1 to 4 C1 to C3 alkyl or alkoxy radicals, A, B and C, independently of one another, can represent an alkylene or alkenylene or alkynylene chain which may be straight or branched, substituted or non-substituted, and can be interrupted by one or more divalent radicals -NR3 -, -S- or -O-, and R1 , R2 and R3 , independently of one another, can represent a hydrogen atom or a substituted or non-substituted alkyl radical or a substituted or non-substituted alkenyl radical or a substituted or non-substituted alkynyl radical or a substituted or non-substituted aryl radical, and the substitutions of the -A-, -B- and -C- chains and the radicals R1 , R2 and R3 are chosen from among one or more halogen atoms or imino, amino or aryl radicals, non-substituted or substituted by one or more halogen atoms or C1 to C3 alkyl radicals, characterised in that : a) a substituted or non-substituted polyamine having the formula II : H(R1 N)-A-NH-B-NH-C-(NR2 )H is reacted with an excess of the dichlorinated gem compound having the formula III : see diagramm : EP0240392,P21,F1 or b) an excess of the aziridine, substituted or non-substituted, is reacted with the compound having the formula IV : see diagramm : EP0240392,P21,F2
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| FR8603155 | 1986-03-06 | ||
| FR8603155A FR2595360B1 (en) | 1986-03-06 | 1986-03-06 | CYCLOPHOSPHAZENE-LIKE COMPOUNDS, PREPARATION METHOD AND PHARMACEUTICAL COMPOSITION CONTAINING THEM |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| AU6968287A true AU6968287A (en) | 1987-09-10 |
Family
ID=9332823
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| AU69682/87A Abandoned AU6968287A (en) | 1986-03-06 | 1987-03-04 | Cyclophosphazene compounds |
Country Status (10)
| Country | Link |
|---|---|
| EP (1) | EP0240392B1 (en) |
| JP (1) | JPS62223186A (en) |
| KR (1) | KR870008902A (en) |
| AT (1) | ATE52515T1 (en) |
| AU (1) | AU6968287A (en) |
| DE (1) | DE3762622D1 (en) |
| ES (1) | ES2015067B3 (en) |
| FR (1) | FR2595360B1 (en) |
| GR (1) | GR3000692T3 (en) |
| HU (1) | HUT44571A (en) |
Families Citing this family (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| FR2655046B1 (en) * | 1989-11-24 | 1992-04-03 | Centre Nat Rech Scient | OXODIAMINODICYCLOPHOSPHAZENES OF MONO-BINO AND DI-BINO CONFIGURATIONS, COMPLEXES DERIVED FROM COMPOUNDS AND APPLICATIONS OF SAID COMPLEXES AND COMPOUNDS THEREOF. |
| FR2706464A1 (en) * | 1993-06-18 | 1994-12-23 | Pf Medicament | New spirodiaza- or spirooxaazaalkylcyclotriphosphazene derivatives substituted by methyl- or dimethylaziridines, their preparation and their use as medicament |
Family Cites Families (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| FR2536751B1 (en) * | 1982-11-25 | 1986-04-25 | Centre Nat Rech Scient | NOVEL TRICYCLOPHOSPHAZENES DERIVATIVES, PROCESS FOR THEIR PREPARATION AND THEIR APPLICATION AS MEDICAMENTS |
-
1986
- 1986-03-06 FR FR8603155A patent/FR2595360B1/en not_active Expired
-
1987
- 1987-03-04 AU AU69682/87A patent/AU6968287A/en not_active Abandoned
- 1987-03-05 ES ES87400490T patent/ES2015067B3/en not_active Expired - Lifetime
- 1987-03-05 AT AT87400490T patent/ATE52515T1/en not_active IP Right Cessation
- 1987-03-05 DE DE8787400490T patent/DE3762622D1/en not_active Expired - Fee Related
- 1987-03-05 EP EP87400490A patent/EP0240392B1/en not_active Expired - Lifetime
- 1987-03-06 HU HU87970A patent/HUT44571A/en unknown
- 1987-03-06 KR KR870002015A patent/KR870008902A/en not_active Application Discontinuation
- 1987-03-06 JP JP62051865A patent/JPS62223186A/en active Pending
-
1990
- 1990-08-02 GR GR90400551T patent/GR3000692T3/en unknown
Also Published As
| Publication number | Publication date |
|---|---|
| JPS62223186A (en) | 1987-10-01 |
| HUT44571A (en) | 1988-03-28 |
| ATE52515T1 (en) | 1990-05-15 |
| EP0240392A1 (en) | 1987-10-07 |
| DE3762622D1 (en) | 1990-06-13 |
| ES2015067B3 (en) | 1990-08-01 |
| FR2595360B1 (en) | 1988-07-01 |
| EP0240392B1 (en) | 1990-05-09 |
| FR2595360A1 (en) | 1987-09-11 |
| GR3000692T3 (en) | 1991-09-27 |
| KR870008902A (en) | 1987-10-22 |
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| ES2113713T3 (en) | THYAMID PREPARATION. | |
| AU6968287A (en) | Cyclophosphazene compounds | |
| IN167606B (en) | ||
| PH19184A (en) | Novel-1(2-carbethoxy 4-benzalkylamido phenoxy)3-amino 2-propanols | |
| ATE31061T1 (en) | CYCLOHEXYLDIOXANES. | |
| EP0115314A3 (en) | Process for the preparation of cholecalciferol derivatives | |
| IL77445A (en) | Process for the preparation of n-sulphonyl-(n-(phosphonomethyl)glycyl)amine derivatives | |
| TW363967B (en) | Bisquaternary ammonium compound of 2,2'- dimethyl-l, l'-binaphthyl and process for their preparation | |
| ATE75730T1 (en) | PROCESS FOR THE PREPARATION OF SUBSTITUTED GUANYLTHIOUREAS. | |
| DE68926016D1 (en) | Halogeno-4-methylpyrazoles and process for their preparation | |
| RO82862B1 (en) | 5-carbamoyloxymethyl-3, 7-dioxa-1-azabicyclo(3.3,0)octanic derivatives and process for preparing the same | |
| RO84591B1 (en) | Ammonium phosphonate derivatives and process for preparing the same | |
| AU555944B2 (en) | Phosphorus derivatives of carbamimidothioic esters | |
| JPS5692300A (en) | Novel cc3 branched cardenolideeglycoside*its manufacture and use |