AU692409B2 - Key intermediates in the manufacture of simvastatin - Google Patents

Key intermediates in the manufacture of simvastatin

Info

Publication number
AU692409B2
AU692409B2 AU21409/97A AU2140997A AU692409B2 AU 692409 B2 AU692409 B2 AU 692409B2 AU 21409/97 A AU21409/97 A AU 21409/97A AU 2140997 A AU2140997 A AU 2140997A AU 692409 B2 AU692409 B2 AU 692409B2
Authority
AU
Australia
Prior art keywords
simvastatin
manufacture
key intermediates
intermediates
key
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Ceased
Application number
AU21409/97A
Other versions
AU2140997A (en
Inventor
Jag Mohan Khanna
S.M. Dileep Kumar
Yatendra Kumar
Satyananda Misra
Rajesh Kumar Thaper
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Ranbaxy Laboratories Ltd
Original Assignee
Ranbaxy Laboratories Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from IN1683DE1996 external-priority patent/IN184809B/en
Priority claimed from US08/816,574 external-priority patent/US5763653A/en
Application filed by Ranbaxy Laboratories Ltd filed Critical Ranbaxy Laboratories Ltd
Publication of AU2140997A publication Critical patent/AU2140997A/en
Application granted granted Critical
Publication of AU692409B2 publication Critical patent/AU692409B2/en
Anticipated expiration legal-status Critical
Ceased legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C235/00—Carboxylic acid amides, the carbon skeleton of the acid part being further substituted by oxygen atoms
    • C07C235/02—Carboxylic acid amides, the carbon skeleton of the acid part being further substituted by oxygen atoms having carbon atoms of carboxamide groups bound to acyclic carbon atoms and singly-bound oxygen atoms bound to the same carbon skeleton
    • C07C235/30—Carboxylic acid amides, the carbon skeleton of the acid part being further substituted by oxygen atoms having carbon atoms of carboxamide groups bound to acyclic carbon atoms and singly-bound oxygen atoms bound to the same carbon skeleton the carbon skeleton being unsaturated and containing rings other than six-membered aromatic rings
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C231/00—Preparation of carboxylic acid amides
    • C07C231/10—Preparation of carboxylic acid amides from compounds not provided for in groups C07C231/02 - C07C231/08
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C231/00—Preparation of carboxylic acid amides
    • C07C231/12—Preparation of carboxylic acid amides by reactions not involving the formation of carboxamide groups
AU21409/97A 1996-05-30 1997-05-14 Key intermediates in the manufacture of simvastatin Ceased AU692409B2 (en)

Applications Claiming Priority (4)

Application Number Priority Date Filing Date Title
US816574 1986-01-06
IN1683/96 1996-05-30
IN1683DE1996 IN184809B (en) 1996-05-30 1996-05-30
US08/816,574 US5763653A (en) 1997-03-13 1997-03-13 Key intermediates in the manufacture of simvastatin

Publications (2)

Publication Number Publication Date
AU2140997A AU2140997A (en) 1998-01-29
AU692409B2 true AU692409B2 (en) 1998-06-04

Family

ID=26324705

Family Applications (1)

Application Number Title Priority Date Filing Date
AU21409/97A Ceased AU692409B2 (en) 1996-05-30 1997-05-14 Key intermediates in the manufacture of simvastatin

Country Status (4)

Country Link
KR (1) KR100503923B1 (en)
CN (1) CN1101805C (en)
AU (1) AU692409B2 (en)
HR (1) HRP970436B1 (en)

Families Citing this family (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
KR20010009846A (en) * 1999-07-14 2001-02-05 구광시 Intermediates useful for manufacturing simvastatin and processes for the preparation thereof
CN103254076A (en) * 2008-05-09 2013-08-21 上海医药工业研究院 Synthesis method for simvastatin ammonium salt, used intermediate and preparation methods for both
CN103864611B (en) * 2013-12-24 2015-11-11 深圳华润九新药业有限公司 The preparation method of a kind of preparation method of Simvastatin alcohol acid compound, composition, composition and application thereof

Also Published As

Publication number Publication date
HRP970436B1 (en) 2003-06-30
KR100503923B1 (en) 2005-10-13
CN1101805C (en) 2003-02-19
HRP970436A2 (en) 1999-06-30
AU2140997A (en) 1998-01-29
CN1173488A (en) 1998-02-18
KR970074750A (en) 1997-12-10

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