AU6728781A - Microbiologically prepared polypeptide with the aminoacid sequence of human interferon - Google Patents

Microbiologically prepared polypeptide with the aminoacid sequence of human interferon

Info

Publication number
AU6728781A
AU6728781A AU67287/81A AU6728781A AU6728781A AU 6728781 A AU6728781 A AU 6728781A AU 67287/81 A AU67287/81 A AU 67287/81A AU 6728781 A AU6728781 A AU 6728781A AU 6728781 A AU6728781 A AU 6728781A
Authority
AU
Australia
Prior art keywords
polypeptide
interferon
human interferon
aminoacid sequence
cdna
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Abandoned
Application number
AU67287/81A
Inventor
Jurgen Groneberg
Joachim Hilfenhaus
Friedrich Wengenmayer
Ernst-Ludwig Winnacker
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Hoechst AG
Original Assignee
Hoechst AG
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Hoechst AG filed Critical Hoechst AG
Publication of AU6728781A publication Critical patent/AU6728781A/en
Abandoned legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09—Recombinant DNA-technology
    • C12N15/10—Processes for the isolation, preparation or purification of DNA or RNA
    • C12N15/1003—Extracting or separating nucleic acids from biological samples, e.g. pure separation or isolation methods; Conditions, buffers or apparatuses therefor
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/52—Cytokines; Lymphokines; Interferons
    • C07K14/555—Interferons [IFN]
    • C07K14/565—IFN-beta

Abstract

There is utilised recombinant DNA technology in the production of interferon, which provides a microbiologically produced polypeptide, all or part of which comprises the amino acid sequence of human interferon, especially fibroblast (???) interferon. There is also provided CDNA which codes for such a polypeptide; a plasmid, especially plasmid pBR 322, which comprises the cDNA; and a microorganism, for example Escherichia coli, especially E. coli K12 or E. coli X1776, which comprises the genetic information required for the production of such a polypeptide. The cDNA is preferably prepared using mRNA obtained from human fibroblasts.
AU67287/81A 1980-02-16 1981-02-13 Microbiologically prepared polypeptide with the aminoacid sequence of human interferon Abandoned AU6728781A (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
DE30058436 1980-02-16
DE19803005843 DE3005843A1 (en) 1980-02-16 1980-02-16 GENERAL PRODUCT OF A HIGHER ORGANISM FROM A MICROORGANISM CONTAINING THIS GENE

Publications (1)

Publication Number Publication Date
AU6728781A true AU6728781A (en) 1981-08-27

Family

ID=6094790

Family Applications (1)

Application Number Title Priority Date Filing Date
AU67287/81A Abandoned AU6728781A (en) 1980-02-16 1981-02-13 Microbiologically prepared polypeptide with the aminoacid sequence of human interferon

Country Status (13)

Country Link
EP (1) EP0034306B1 (en)
JP (1) JPS56131522A (en)
AT (1) ATE26999T1 (en)
AU (1) AU6728781A (en)
BE (1) BE887530A (en)
DE (2) DE3005843A1 (en)
ES (3) ES499289A0 (en)
FR (1) FR2482132A1 (en)
GB (1) GB2069504A (en)
IT (1) IT1141976B (en)
NL (1) NL8100719A (en)
SE (1) SE8101004L (en)
ZA (1) ZA81973B (en)

Families Citing this family (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DK33181A (en) * 1980-02-06 1981-08-07 Searle & Co PROCEDURE FOR THE PREPARATION OF AN INTERFERONOUS PROTEIN
IL62552A0 (en) * 1980-04-03 1981-06-29 Biogen Nv Dna sequences,recombinant dna molecules and processes for producing human fibroblast interferon-like polypeptides
ATE25985T1 (en) * 1980-06-12 1987-04-15 Japan Found Cancer PLASMID.
GR81946B (en) * 1980-09-25 1984-12-12 Genentech Inc
EP0098876A1 (en) * 1982-01-19 1984-01-25 Cetus Corporation Multiclass hybrid interferons
US6432677B1 (en) 1982-03-08 2002-08-13 Genentech, Inc. Non-human animal interferons
IE54592B1 (en) * 1982-03-08 1989-12-06 Genentech Inc Anumal interferons, processes involved in their production, compositions containing them, dna sequences coding therefor and espression vehicles containing such sequences and cells transformed thereby
US5827694A (en) * 1982-03-08 1998-10-27 Genentech, Inc. DNA encoding non-human animal interferons, vectors and hosts therefor, and recombinant production of IFN polypeptides
DE3220116A1 (en) * 1982-05-28 1983-12-01 Dr. Karl Thomae Gmbh, 7950 Biberach MICROBIOLOGICALLY MANUFACTURED (ALPHA) AND SS INTERFERONES, DNA SEQUENCES CODING FOR THESE INTERFERONES, MICROORGANISMS CONTAINING THIS GENETIC INFORMATION, AND METHOD FOR THE PRODUCTION THEREOF
US5831023A (en) * 1982-11-01 1998-11-03 Genentech, Inc. Recombinant animal interferon polypeptides

Family Cites Families (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FI77877C (en) * 1979-04-20 1989-05-10 Technobiotic Ltd Process for the preparation and purification of human Le-shaped interferon protein.
AU538665B2 (en) * 1979-10-30 1984-08-23 Juridical Foundation, Japanese Foundation For Cancer Research Human interferon dna
IL58765A (en) * 1979-11-21 1986-09-30 Yeda Res & Dev Process for the production of essentially pure messenger rna of human fibroblast interferon and process for the production of interferon beta
PH21848A (en) * 1980-01-08 1988-03-17 Biogen Nv Dna sequences and recombinant dna molecules
DK33181A (en) * 1980-02-06 1981-08-07 Searle & Co PROCEDURE FOR THE PREPARATION OF AN INTERFERONOUS PROTEIN
AU545912B2 (en) * 1980-03-10 1985-08-08 Cetus Corporation Cloned heterologous jive products in bacillies
IL62552A0 (en) * 1980-04-03 1981-06-29 Biogen Nv Dna sequences,recombinant dna molecules and processes for producing human fibroblast interferon-like polypeptides

Also Published As

Publication number Publication date
ES8205430A1 (en) 1982-06-01
FR2482132A1 (en) 1981-11-13
ES499290A0 (en) 1982-06-01
EP0034306B1 (en) 1987-05-06
ES499285A0 (en) 1983-01-01
BE887530A (en) 1981-08-17
ES8205429A1 (en) 1982-06-01
ZA81973B (en) 1982-03-31
DE3176161D1 (en) 1987-06-11
ATE26999T1 (en) 1987-05-15
SE8101004L (en) 1981-08-17
ES8302089A1 (en) 1983-01-01
EP0034306A3 (en) 1981-11-04
ES499289A0 (en) 1982-06-01
JPS56131522A (en) 1981-10-15
NL8100719A (en) 1981-09-16
IT1141976B (en) 1986-10-08
IT8119759A0 (en) 1981-02-13
GB2069504A (en) 1981-08-26
EP0034306A2 (en) 1981-08-26
DE3005843A1 (en) 1981-09-10

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