AU6720998A - Process for synthesising pure enantiomer anthracycline - Google Patents
Process for synthesising pure enantiomer anthracyclineInfo
- Publication number
- AU6720998A AU6720998A AU67209/98A AU6720998A AU6720998A AU 6720998 A AU6720998 A AU 6720998A AU 67209/98 A AU67209/98 A AU 67209/98A AU 6720998 A AU6720998 A AU 6720998A AU 6720998 A AU6720998 A AU 6720998A
- Authority
- AU
- Australia
- Prior art keywords
- synthesising
- anthracycline
- pure enantiomer
- enantiomer
- pure
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Abandoned
Links
- 229940045799 anthracyclines and related substance Drugs 0.000 title 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C50/00—Quinones
- C07C50/26—Quinones containing groups having oxygen atoms singly bound to carbon atoms
- C07C50/36—Quinones containing groups having oxygen atoms singly bound to carbon atoms the quinoid structure being part of a condensed ring system having four or more rings
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C43/00—Ethers; Compounds having groups, groups or groups
- C07C43/02—Ethers
- C07C43/20—Ethers having an ether-oxygen atom bound to a carbon atom of a six-membered aromatic ring
- C07C43/215—Ethers having an ether-oxygen atom bound to a carbon atom of a six-membered aromatic ring having unsaturation outside the six-membered aromatic rings
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C43/00—Ethers; Compounds having groups, groups or groups
- C07C43/02—Ethers
- C07C43/20—Ethers having an ether-oxygen atom bound to a carbon atom of a six-membered aromatic ring
- C07C43/23—Ethers having an ether-oxygen atom bound to a carbon atom of a six-membered aromatic ring containing hydroxy or O-metal groups
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C45/00—Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds
- C07C45/61—Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds by reactions not involving the formation of >C = O groups
- C07C45/67—Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds by reactions not involving the formation of >C = O groups by isomerisation; by change of size of the carbon skeleton
- C07C45/673—Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds by reactions not involving the formation of >C = O groups by isomerisation; by change of size of the carbon skeleton by change of size of the carbon skeleton
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C46/00—Preparation of quinones
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C47/00—Compounds having —CHO groups
- C07C47/52—Compounds having —CHO groups bound to carbon atoms of six—membered aromatic rings
- C07C47/575—Compounds having —CHO groups bound to carbon atoms of six—membered aromatic rings containing ether groups, groups, groups, or groups
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07F—ACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
- C07F7/00—Compounds containing elements of Groups 4 or 14 of the Periodic Table
- C07F7/02—Silicon compounds
- C07F7/08—Compounds having one or more C—Si linkages
- C07F7/18—Compounds having one or more C—Si linkages as well as one or more C—O—Si linkages
- C07F7/1804—Compounds having Si-O-C linkages
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Chemical Kinetics & Catalysis (AREA)
Applications Claiming Priority (3)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
DE19708496 | 1997-03-03 | ||
DE19708496A DE19708496A1 (en) | 1997-03-03 | 1997-03-03 | Process for enanthanum-pure anthracylin synthesis |
PCT/EP1998/000925 WO1998039337A1 (en) | 1997-03-03 | 1998-02-18 | Process for synthesising pure enantiomer anthracycline |
Publications (1)
Publication Number | Publication Date |
---|---|
AU6720998A true AU6720998A (en) | 1998-09-22 |
Family
ID=7822027
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
AU67209/98A Abandoned AU6720998A (en) | 1997-03-03 | 1998-02-18 | Process for synthesising pure enantiomer anthracycline |
Country Status (3)
Country | Link |
---|---|
AU (1) | AU6720998A (en) |
DE (1) | DE19708496A1 (en) |
WO (1) | WO1998039337A1 (en) |
Families Citing this family (8)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US6441245B1 (en) | 1997-10-24 | 2002-08-27 | United Therapeutics Corporation | Process for stereoselective synthesis of prostacyclin derivatives |
ES2198760T3 (en) * | 1997-10-24 | 2004-02-01 | United Therapeutics Corporation | PROCEDURE FOR STEREOSELECTIVE SYNTHESIS OF PROSTACICLINE DERIVATIVES. |
US6700025B2 (en) | 2001-01-05 | 2004-03-02 | United Therapeutics Corporation | Process for stereoselective synthesis of prostacyclin derivatives |
EP3287434A1 (en) | 2007-12-17 | 2018-02-28 | United Therapeutics Corporation | Process to prepare treprostinil, the active ingredient in remodulin ® |
WO2011153363A1 (en) | 2010-06-03 | 2011-12-08 | United Therapeutics Corporation | Treprostinil production |
EP2681204B1 (en) | 2011-03-02 | 2016-04-27 | United Therapeutics Corporation | Synthesis of intermediate for treprostinil production |
AT513522A1 (en) * | 2012-10-15 | 2014-05-15 | Produkem Molekulares Design Gmbh | New anthracycline derivatives |
ES2778274T3 (en) | 2014-10-20 | 2020-08-10 | United Therapeutics Corp | Synthesis of intermediate products to produce prostacyclin derivatives |
-
1997
- 1997-03-03 DE DE19708496A patent/DE19708496A1/en not_active Withdrawn
-
1998
- 1998-02-18 AU AU67209/98A patent/AU6720998A/en not_active Abandoned
- 1998-02-18 WO PCT/EP1998/000925 patent/WO1998039337A1/en active Application Filing
Also Published As
Publication number | Publication date |
---|---|
DE19708496A1 (en) | 1998-09-10 |
WO1998039337A1 (en) | 1998-09-11 |
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