AU6709794A - Erythropoietin muteins with enhanced activity - Google Patents

Erythropoietin muteins with enhanced activity

Info

Publication number
AU6709794A
AU6709794A AU67097/94A AU6709794A AU6709794A AU 6709794 A AU6709794 A AU 6709794A AU 67097/94 A AU67097/94 A AU 67097/94A AU 6709794 A AU6709794 A AU 6709794A AU 6709794 A AU6709794 A AU 6709794A
Authority
AU
Australia
Prior art keywords
enhanced activity
erythropoietin muteins
muteins
erythropoietin
enhanced
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Abandoned
Application number
AU67097/94A
Inventor
Jean-Paul R Boissel
H. Franklin Bunn
Mark O Showers
Danyi Wen
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Brigham and Womens Hospital Inc
Original Assignee
Brigham and Womens Hospital Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Brigham and Womens Hospital Inc filed Critical Brigham and Womens Hospital Inc
Publication of AU6709794A publication Critical patent/AU6709794A/en
Abandoned legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/475—Growth factors; Growth regulators
    • C07K14/505—Erythropoietin [EPO]
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides

Landscapes

  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Organic Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Biochemistry (AREA)
  • Biophysics (AREA)
  • Zoology (AREA)
  • Genetics & Genomics (AREA)
  • Medicinal Chemistry (AREA)
  • Molecular Biology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Toxicology (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Peptides Or Proteins (AREA)
AU67097/94A 1993-04-21 1994-04-21 Erythropoietin muteins with enhanced activity Abandoned AU6709794A (en)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US4980293A 1993-04-21 1993-04-21
US049802 1993-04-21
PCT/US1994/004361 WO1994024160A2 (en) 1993-04-21 1994-04-21 Erythropoietin muteins with enhanced activity

Publications (1)

Publication Number Publication Date
AU6709794A true AU6709794A (en) 1994-11-08

Family

ID=21961825

Family Applications (1)

Application Number Title Priority Date Filing Date
AU67097/94A Abandoned AU6709794A (en) 1993-04-21 1994-04-21 Erythropoietin muteins with enhanced activity

Country Status (2)

Country Link
AU (1) AU6709794A (en)
WO (1) WO1994024160A2 (en)

Families Citing this family (22)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5614184A (en) * 1992-07-28 1997-03-25 New England Deaconess Hospital Recombinant human erythropoietin mutants and therapeutic methods employing them
US6153407A (en) * 1992-07-28 2000-11-28 Beth Israel Deaconess Medical Center Erythropoietin DNA having modified 5' and 3' sequences and its use to prepare EPO therapeutics
JP4301347B2 (en) 1996-03-14 2009-07-22 ジェネンテク， インコーポレイテッド Applications of GDNF and GDNF receptor
GB2318352A (en) * 1996-06-25 1998-04-22 Dejan Markovic Polypeptides mimicking the activity of human erythropoietin
US6967092B1 (en) 1996-10-25 2005-11-22 Mc Kearn John P Multi-functional chimeric hematopoietic receptor agonists
US5952226A (en) * 1996-11-05 1999-09-14 Modex Therapeutiques Hypoxia responsive EPO producing cells
KR100524041B1 (en) * 1999-05-07 2005-10-27 제넨테크, 인크. Novel Chimpanzee Erythropoietin (CHEPO) Polypeptides and Nucleic Acids Encoding the Same
EP1177285A1 (en) * 1999-05-07 2002-02-06 Genentech, Inc. Chimpanzee erythropoietin (chepo) polypeptides and nucleic acids encoding the same
US6831060B2 (en) 1999-05-07 2004-12-14 Genentech, Inc. Chimpanzee erythropoietin (CHEPO) polypeptides and nucleic acids encoding the same
US6555343B1 (en) 1999-05-07 2003-04-29 Genentech Inc. Chimpanzee erythropoietin (CHEPO) polypeptides and nucleic acids encoding the same
WO2001036489A2 (en) * 1999-11-12 2001-05-25 Merck Patent Gmbh Erythropoietin forms with improved properties
US6992174B2 (en) 2001-03-30 2006-01-31 Emd Lexigen Research Center Corp. Reducing the immunogenicity of fusion proteins
ES2545090T3 (en) 2001-12-21 2015-09-08 Human Genome Sciences, Inc. Albumin and GCSF fusion proteins
MXPA05000063A (en) * 2002-07-01 2005-04-08 Kenneth S Warren Inst Inc Recombinant tissue protective cytokines and encoding nucleic acids thereof for protection, restoration, and enhancement of responsive cells, tissues, and organs.
AU2003246486A1 (en) * 2002-07-19 2004-02-09 Cangene Corporation Pegylated erythropoietic compounds
WO2007052154A2 (en) * 2005-04-29 2007-05-10 University Of Medicine And Dentistry Of New Jersey Erythropoietin-derived short peptide and its mimics as immuno/inflammatory modulators
US9345745B2 (en) * 2005-04-29 2016-05-24 Bo Wang Methods for treating inflammatory disorders and traumatic brain injury using stabilized non-hematopoietic EPO short peptides
WO2007136752A2 (en) 2006-05-19 2007-11-29 Glycofi, Inc. Erythropoietin compositions
EP2120998B1 (en) * 2006-11-28 2013-08-07 HanAll Biopharma Co., Ltd. Modified erythropoietin polypeptides and uses thereof for treatment
CN102232085A (en) * 2008-09-26 2011-11-02 Ambrx公司 Modified animal erythropoietin polypeptides and their uses
AR113091A1 (en) * 2018-09-27 2020-01-22 Univ Nacional Del Litoral MODIFIED HUMAN ERYTHROPOYETIN
WO2022159414A1 (en) 2021-01-22 2022-07-28 University Of Rochester Erythropoietin for gastroinfestinal dysfunction

Family Cites Families (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4703008A (en) * 1983-12-13 1987-10-27 Kiren-Amgen, Inc. DNA sequences encoding erythropoietin
NZ210501A (en) * 1983-12-13 1991-08-27 Kirin Amgen Inc Erythropoietin produced by procaryotic or eucaryotic expression of an exogenous dna sequence
US4835260A (en) * 1987-03-20 1989-05-30 Genetics Institute, Inc. Erythropoietin composition
DE3923963A1 (en) * 1989-07-20 1991-01-31 Behringwerke Ag MUTEINE OF HUMAN ERYTHROPOETIN, THEIR PRODUCTION AND THEIR USE
KR100263845B1 (en) * 1989-10-13 2000-08-16 스튜어트 엘.왓트 Erythropoietin isoforms and preparation method thereof and pharmaceutical composition containing it
JPH03151399A (en) * 1989-11-07 1991-06-27 Snow Brand Milk Prod Co Ltd Mutant human erythropoietin

Also Published As

Publication number Publication date
WO1994024160A2 (en) 1994-10-27
WO1994024160A3 (en) 1995-01-05

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