AU6237198A - Large-scale purification of full length oligonucleotides by solid-liquid affinity extraction - Google Patents

Large-scale purification of full length oligonucleotides by solid-liquid affinity extraction

Info

Publication number
AU6237198A
AU6237198A AU62371/98A AU6237198A AU6237198A AU 6237198 A AU6237198 A AU 6237198A AU 62371/98 A AU62371/98 A AU 62371/98A AU 6237198 A AU6237198 A AU 6237198A AU 6237198 A AU6237198 A AU 6237198A
Authority
AU
Australia
Prior art keywords
solid
full length
scale purification
liquid affinity
length oligonucleotides
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Abandoned
Application number
AU62371/98A
Other languages
English (en)
Inventor
Danhua Chen
Douglas L. Cole
Githa Susan Srivatsa
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Ionis Pharmaceuticals Inc
Original Assignee
Isis Pharmaceuticals Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Isis Pharmaceuticals Inc filed Critical Isis Pharmaceuticals Inc
Publication of AU6237198A publication Critical patent/AU6237198A/en
Abandoned legal-status Critical Current

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K48/00—Medicinal preparations containing genetic material which is inserted into cells of the living body to treat genetic diseases; Gene therapy
    • A61K48/0091—Purification or manufacturing processes for gene therapy compositions
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
    • C12Q1/6813—Hybridisation assays
    • C12Q1/6834—Enzymatic or biochemical coupling of nucleic acids to a solid phase
    • C12Q1/6837—Enzymatic or biochemical coupling of nucleic acids to a solid phase using probe arrays or probe chips

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Genetics & Genomics (AREA)
  • Organic Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Zoology (AREA)
  • Biotechnology (AREA)
  • Molecular Biology (AREA)
  • Wood Science & Technology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Medicinal Chemistry (AREA)
  • Immunology (AREA)
  • Veterinary Medicine (AREA)
  • Physics & Mathematics (AREA)
  • Analytical Chemistry (AREA)
  • Biophysics (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Microbiology (AREA)
  • Epidemiology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Manufacturing & Machinery (AREA)
  • Biochemistry (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • General Engineering & Computer Science (AREA)
  • Saccharide Compounds (AREA)
AU62371/98A 1996-12-19 1997-12-18 Large-scale purification of full length oligonucleotides by solid-liquid affinity extraction Abandoned AU6237198A (en)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US76995196A 1996-12-19 1996-12-19
US08769951 1996-12-19
PCT/US1997/023284 WO1998027425A1 (fr) 1996-12-19 1997-12-18 Purification a grande echelle d'oligonucleotides de longueur totale par extraction par affinite solide-liquide

Publications (1)

Publication Number Publication Date
AU6237198A true AU6237198A (en) 1998-07-15

Family

ID=25087017

Family Applications (1)

Application Number Title Priority Date Filing Date
AU62371/98A Abandoned AU6237198A (en) 1996-12-19 1997-12-18 Large-scale purification of full length oligonucleotides by solid-liquid affinity extraction

Country Status (2)

Country Link
AU (1) AU6237198A (fr)
WO (1) WO1998027425A1 (fr)

Families Citing this family (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE19850186A1 (de) * 1998-10-30 2000-05-25 Roche Diagnostics Gmbh Neue Primer und Sonden zum Nachweis von HIV
WO2006006948A2 (fr) 2002-11-14 2006-01-19 Dharmacon, Inc. Methodes et compositions permettant de selectionner des arnsi presentant une fonctionnalite amelioree
AU2003295600A1 (en) * 2002-11-14 2004-06-15 Dharmacon, Inc. Functional and hyperfunctional sirna
CN103068981A (zh) 2010-07-28 2013-04-24 爱尔康研究有限公司 靶向VEGFA的siRNA及用于体内治疗的方法

Also Published As

Publication number Publication date
WO1998027425A1 (fr) 1998-06-25

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