AU6163398A - Identification of inhibitors of protein tyrosine kinase 2 - Google Patents

Identification of inhibitors of protein tyrosine kinase 2

Info

Publication number
AU6163398A
AU6163398A AU61633/98A AU6163398A AU6163398A AU 6163398 A AU6163398 A AU 6163398A AU 61633/98 A AU61633/98 A AU 61633/98A AU 6163398 A AU6163398 A AU 6163398A AU 6163398 A AU6163398 A AU 6163398A
Authority
AU
Australia
Prior art keywords
inhibitors
identification
tyrosine kinase
protein tyrosine
protein
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Abandoned
Application number
AU61633/98A
Inventor
Le T. Duong
Gideon A Rodan
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Merck and Co Inc
Original Assignee
Merck and Co Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Merck and Co Inc filed Critical Merck and Co Inc
Publication of AU6163398A publication Critical patent/AU6163398A/en
Abandoned legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/48—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving transferase
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P19/00—Drugs for skeletal disorders
    • A61P19/08—Drugs for skeletal disorders for bone diseases, e.g. rachitism, Paget's disease
    • A61P19/10—Drugs for skeletal disorders for bone diseases, e.g. rachitism, Paget's disease for osteoporosis
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • General Health & Medical Sciences (AREA)
  • Rheumatology (AREA)
  • Public Health (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • General Chemical & Material Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Veterinary Medicine (AREA)
  • Physical Education & Sports Medicine (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Orthopedic Medicine & Surgery (AREA)
  • Zoology (AREA)
  • Wood Science & Technology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Biotechnology (AREA)
  • Immunology (AREA)
  • Microbiology (AREA)
  • Molecular Biology (AREA)
  • Biophysics (AREA)
  • Analytical Chemistry (AREA)
  • Biochemistry (AREA)
  • General Engineering & Computer Science (AREA)
  • Genetics & Genomics (AREA)
  • Physics & Mathematics (AREA)
  • Pain & Pain Management (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Peptides Or Proteins (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
AU61633/98A 1997-02-11 1998-02-09 Identification of inhibitors of protein tyrosine kinase 2 Abandoned AU6163398A (en)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US3756097P 1997-02-11 1997-02-11
US60037560 1997-02-11
PCT/US1998/002797 WO1998035056A1 (en) 1997-02-11 1998-02-09 Identification of inhibitors of protein tyrosine kinase 2

Publications (1)

Publication Number Publication Date
AU6163398A true AU6163398A (en) 1998-08-26

Family

ID=21895000

Family Applications (1)

Application Number Title Priority Date Filing Date
AU61633/98A Abandoned AU6163398A (en) 1997-02-11 1998-02-09 Identification of inhibitors of protein tyrosine kinase 2

Country Status (5)

Country Link
EP (1) EP0968304A1 (en)
JP (1) JP2001512309A (en)
AU (1) AU6163398A (en)
CA (1) CA2277544A1 (en)
WO (1) WO1998035056A1 (en)

Families Citing this family (13)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO1998035659A1 (en) 1997-02-18 1998-08-20 Lxr Biotechnology Inc. Bak promotor expression system
EP1630559A3 (en) * 1998-12-30 2006-06-07 Sugen, Inc. PYK2 (RAFTK) and inflammation
EP1141722A1 (en) * 1998-12-31 2001-10-10 Sugen, Inc. Pyk2 (raftk) and inflammation
US6861442B1 (en) 1998-12-30 2005-03-01 Sugen, Inc. PYK2 and inflammation
JP2004511753A (en) * 2000-05-04 2004-04-15 イエール　ユニバーシティー Protein chip for protein activity screening
WO2002038797A2 (en) * 2000-10-23 2002-05-16 Bristol-Myers Squibb Company Modulators of bruton's tyrosine kinase, their identification and use
JP2005500041A (en) 2001-06-29 2005-01-06 アブ サイエンス Potent, selective and non-toxic C-KIT inhibitor
US20040266771A1 (en) * 2001-06-29 2004-12-30 Alain Moussy Use of tyrosine kinase inhibitors for treating bone loss
PT1401413E (en) 2001-06-29 2007-02-28 Ab Science Use of tyrosine kinase inhibitions for treating allergic diseases
ATE343415T1 (en) 2001-06-29 2006-11-15 Ab Science THE USE OF C-KIT INHIBITORS FOR THE TREATMENT OF INFLAMMATORY BOWEL DISEASE
ATE330608T1 (en) 2001-06-29 2006-07-15 Ab Science THE USE OF N-PHENYL-2-PYRIMIDINE-AMINE DERIVATIVES FOR THE TREATMENT OF INFLAMMATORY DISEASES
US20050170431A1 (en) * 2003-02-28 2005-08-04 Plexxikon, Inc. PYK2 crystal structure and uses
CA2571482A1 (en) * 2004-06-21 2005-12-29 Pharmacia & Upjohn Company Llc Pyk2 inhibitors for stimulation of osteoblast function

Also Published As

Publication number Publication date
CA2277544A1 (en) 1998-08-13
EP0968304A1 (en) 2000-01-05
WO1998035056A1 (en) 1998-08-13
JP2001512309A (en) 2001-08-21

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