AU5994099A - A novel ret-independent signaling pathway for gdnf - Google Patents

A novel ret-independent signaling pathway for gdnf

Info

Publication number
AU5994099A
AU5994099A AU59940/99A AU5994099A AU5994099A AU 5994099 A AU5994099 A AU 5994099A AU 59940/99 A AU59940/99 A AU 59940/99A AU 5994099 A AU5994099 A AU 5994099A AU 5994099 A AU5994099 A AU 5994099A
Authority
AU
Australia
Prior art keywords
gdnf
signaling pathway
independent signaling
ret
novel
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Abandoned
Application number
AU59940/99A
Inventor
Urmas Arumae
Dmitri Poteriaev
Mart Saarma
Alexey Vladimirovich Titievsky
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Individual
Original Assignee
Individual
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Individual filed Critical Individual
Publication of AU5994099A publication Critical patent/AU5994099A/en
Abandoned legal-status Critical Current

Links

Classifications

    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/68—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving proteins, peptides or amino acids
    • G01N33/6803—General methods of protein analysis not limited to specific proteins or families of proteins
    • G01N33/6842—Proteomic analysis of subsets of protein mixtures with reduced complexity, e.g. membrane proteins, phosphoproteins, organelle proteins
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/08—Antiepileptics; Anticonvulsants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/14—Drugs for disorders of the nervous system for treating abnormal movements, e.g. chorea, dyskinesia
    • A61P25/16—Anti-Parkinson drugs
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/475—Growth factors; Growth regulators
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/68—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving proteins, peptides or amino acids
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N2500/00—Screening for compounds of potential therapeutic value
AU59940/99A 1998-10-01 1999-10-01 A novel ret-independent signaling pathway for gdnf Abandoned AU5994099A (en)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US10264798P 1998-10-01 1998-10-01
US60102647 1998-10-01
PCT/IB1999/001681 WO2000020867A1 (en) 1998-10-01 1999-10-01 A novel ret-independent signaling pathway for gdnf

Publications (1)

Publication Number Publication Date
AU5994099A true AU5994099A (en) 2000-04-26

Family

ID=22290937

Family Applications (1)

Application Number Title Priority Date Filing Date
AU59940/99A Abandoned AU5994099A (en) 1998-10-01 1999-10-01 A novel ret-independent signaling pathway for gdnf

Country Status (4)

Country Link
EP (1) EP1119772A1 (en)
JP (1) JP2002526775A (en)
AU (1) AU5994099A (en)
WO (1) WO2000020867A1 (en)

Families Citing this family (12)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB9614871D0 (en) 1996-07-15 1996-09-04 Smithkline Beecham Plc Compounds
US20020072051A1 (en) * 2000-06-23 2002-06-13 Bulawa Christine Ellen Screen for identifying inhibitors of GPI anchoring
GB0102480D0 (en) * 2001-01-31 2001-03-14 Cyclacel Ltd Marker
EP1925315A3 (en) * 2001-02-27 2009-11-18 Blanchette Rockefeller Neurosciences Institute Alzheimer's disease diagnosis based on mitogen-activated protein kinase phosphorylation
CN1549721B (en) 2001-02-27 2012-03-07 布朗歇特洛克菲勒神经科学研究所 Alzheimer's disease diagnosis based on mitogen-activated protein kinase phosphorylation
WO2004078775A2 (en) * 2003-03-05 2004-09-16 Licentia Ltd Intracellular signaling-induced ret-independent gdnf receptor-effected morphological changes
US20090029873A1 (en) 2005-10-11 2009-01-29 Blanchette Rockefeller Neurosciences Institute Alzheimer's Disease-Specific Alterations of the Erk1/Erk2 Phosphorylation Ratio-Alzheimer's Disease-Specific Molecular Biomarkers (Adsmb)
EP3586839A1 (en) 2008-07-28 2020-01-01 Blanchette Rockefeller Neurosciences, Institute Pkc-activating compounds for the treatment of neurodegenerative diseases
EP2669386A1 (en) 2008-07-28 2013-12-04 Blanchette Rockefeller Neurosciences Institute Stimulus-elicited genomic profile markers of alzheimer's disease
WO2011041761A1 (en) 2009-10-02 2011-04-07 Blanchette Rockefeller Neurosciences Institute Fibroblast growth patterns for diagnosis of alzheimer's disease
CA2856235A1 (en) 2011-11-13 2013-05-16 Blanchette Rockefeller Neurosciences Institute Esters of dcpla for the treatment of neurodegenerative disorders
TWI815793B (en) 2016-03-31 2023-09-21 美商恩格姆生物製藥公司 Binding proteins and methods of use thereof

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CA2237641A1 (en) * 1995-11-13 1997-05-22 Urmas Arumae Glial cell line-derived neurotrophic factor receptors
ATE312915T1 (en) * 1997-02-18 2005-12-15 Genentech Inc NEURTURIN RECEPTOR

Also Published As

Publication number Publication date
WO2000020867A1 (en) 2000-04-13
EP1119772A1 (en) 2001-08-01
JP2002526775A (en) 2002-08-20

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Legal Events

Date Code Title Description
MK6 Application lapsed section 142(2)(f)/reg. 8.3(3) - pct applic. not entering national phase