AU587833B2 - Method for separation of 3S, 7R-3,4,5,6,7,8,9,10,11,12-Deca hydro-7,14,16-trihydroxy-3-methyl-1H-2- benzoxacyclotetradecin-1-one from its 3S, 7S-diastereomer - Google Patents

Method for separation of 3S, 7R-3,4,5,6,7,8,9,10,11,12-Deca hydro-7,14,16-trihydroxy-3-methyl-1H-2- benzoxacyclotetradecin-1-one from its 3S, 7S-diastereomer

Info

Publication number
AU587833B2
AU587833B2 AU58964/86A AU5896486A AU587833B2 AU 587833 B2 AU587833 B2 AU 587833B2 AU 58964/86 A AU58964/86 A AU 58964/86A AU 5896486 A AU5896486 A AU 5896486A AU 587833 B2 AU587833 B2 AU 587833B2
Authority
AU
Australia
Prior art keywords
benzoxacyclotetradecin
trihydroxy
diastereomer
methyl
separation
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Ceased
Application number
AU58964/86A
Other languages
English (en)
Other versions
AU5896486A (en
Inventor
Cristina Dr. Angeli
Enio Dr. Decorte
Flavio Dr. Miomas
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Crc Di Ricerca Chimica SpA Cia
Original Assignee
CRC Compagnie di Ricerca Chimica SpA
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by CRC Compagnie di Ricerca Chimica SpA filed Critical CRC Compagnie di Ricerca Chimica SpA
Publication of AU5896486A publication Critical patent/AU5896486A/en
Application granted granted Critical
Publication of AU587833B2 publication Critical patent/AU587833B2/en
Anticipated expiration legal-status Critical
Ceased legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D313/00—Heterocyclic compounds containing rings of more than six members having one oxygen atom as the only ring hetero atom
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P15/00—Drugs for genital or sexual disorders; Contraceptives

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  • Organic Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Endocrinology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Medicinal Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Reproductive Health (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pyrane Compounds (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
AU58964/86A 1986-06-05 1986-06-18 Method for separation of 3S, 7R-3,4,5,6,7,8,9,10,11,12-Deca hydro-7,14,16-trihydroxy-3-methyl-1H-2- benzoxacyclotetradecin-1-one from its 3S, 7S-diastereomer Ceased AU587833B2 (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
EP86107692A EP0248916A1 (en) 1986-06-05 1986-06-05 Method for separation of 3S,7R-3,4,5,6,7,8,9,10,11,12-decahydro-7,14,16-trihydroxy-3-methyl-1H-2-benzoxacyclotetradecin-1-one from its 3S,7S-diastereomer
ZA864357A ZA864357B (ref) 1986-06-05 1986-06-11

Publications (2)

Publication Number Publication Date
AU5896486A AU5896486A (en) 1987-12-24
AU587833B2 true AU587833B2 (en) 1989-08-31

Family

ID=26102148

Family Applications (1)

Application Number Title Priority Date Filing Date
AU58964/86A Ceased AU587833B2 (en) 1986-06-05 1986-06-18 Method for separation of 3S, 7R-3,4,5,6,7,8,9,10,11,12-Deca hydro-7,14,16-trihydroxy-3-methyl-1H-2- benzoxacyclotetradecin-1-one from its 3S, 7S-diastereomer

Country Status (4)

Country Link
EP (1) EP0248916A1 (ref)
JP (1) JPS62298586A (ref)
AU (1) AU587833B2 (ref)
ZA (1) ZA864357B (ref)

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
AU618363B2 (en) * 1988-03-11 1991-12-19 C.R.C. Compagnia Di Ricerca Chimica S.P.A A process for the separation of macrocyclic diastereomers

Families Citing this family (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5136056A (en) * 1988-03-11 1992-08-04 C.R.C. Compagnia Di Ricerca Chimici S.P.A. Zeranol production
US5210225A (en) * 1988-03-11 1993-05-11 C.R.C. Compagnia Di Ricera Chimica S.P.A. Zeranol production
WO2008021213A1 (en) * 2006-08-11 2008-02-21 Nicolas Winssinger Macrocyclic compounds useful as inhibitors of kinases and hsp90

Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3687982A (en) * 1971-03-09 1972-08-29 Commercial Solvents Corp Separation of mixed diastereoisomers of zearalanol
FR2571372A1 (fr) * 1984-07-25 1986-04-11 Panmedica Sa Procede de separation des diastereoisomeres du zearalanol

Family Cites Families (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4052414A (en) * 1971-03-01 1977-10-04 Imc Chemical Group, Inc. Cis-zearalanone, cis-zearalenol, and cis-zearalene

Patent Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3687982A (en) * 1971-03-09 1972-08-29 Commercial Solvents Corp Separation of mixed diastereoisomers of zearalanol
FR2571372A1 (fr) * 1984-07-25 1986-04-11 Panmedica Sa Procede de separation des diastereoisomeres du zearalanol

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
AU618363B2 (en) * 1988-03-11 1991-12-19 C.R.C. Compagnia Di Ricerca Chimica S.P.A A process for the separation of macrocyclic diastereomers

Also Published As

Publication number Publication date
JPS62298586A (ja) 1987-12-25
AU5896486A (en) 1987-12-24
EP0248916A1 (en) 1987-12-16
ZA864357B (ref) 1986-12-09

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