AU5737696A - Nucleic acids for treating obesity - Google Patents

Nucleic acids for treating obesity

Info

Publication number
AU5737696A
AU5737696A AU57376/96A AU5737696A AU5737696A AU 5737696 A AU5737696 A AU 5737696A AU 57376/96 A AU57376/96 A AU 57376/96A AU 5737696 A AU5737696 A AU 5737696A AU 5737696 A AU5737696 A AU 5737696A
Authority
AU
Australia
Prior art keywords
nucleic acids
treating obesity
obesity
treating
nucleic
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Abandoned
Application number
AU57376/96A
Inventor
Klaus W. Giese
Lewis T. Williams
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Novartis Vaccines and Diagnostics Inc
Original Assignee
Chiron Corp
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Chiron Corp filed Critical Chiron Corp
Publication of AU5737696A publication Critical patent/AU5737696A/en
Abandoned legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/575—Hormones
    • C07K14/5759—Products of obesity genes, e.g. leptin, obese (OB), tub, fat
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A61P3/04—Anorexiants; Antiobesity agents
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/43504—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from invertebrates
    • C07K14/43563—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from invertebrates from insects
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/705—Receptors; Cell surface antigens; Cell surface determinants
    • C07K14/72—Receptors; Cell surface antigens; Cell surface determinants for hormones
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2319/00—Fusion polypeptide
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2319/00—Fusion polypeptide
    • C07K2319/01—Fusion polypeptide containing a localisation/targetting motif
    • C07K2319/02—Fusion polypeptide containing a localisation/targetting motif containing a signal sequence
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2799/00—Uses of viruses
    • C12N2799/02—Uses of viruses as vector
    • C12N2799/021—Uses of viruses as vector for the expression of a heterologous nucleic acid
    • C12N2799/026—Uses of viruses as vector for the expression of a heterologous nucleic acid where the vector is derived from a baculovirus

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Organic Chemistry (AREA)
  • Zoology (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Biophysics (AREA)
  • Molecular Biology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Genetics & Genomics (AREA)
  • Biochemistry (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Toxicology (AREA)
  • Child & Adolescent Psychology (AREA)
  • Obesity (AREA)
  • Endocrinology (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Diabetes (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Engineering & Computer Science (AREA)
  • Hematology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Animal Behavior & Ethology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Insects & Arthropods (AREA)
  • Tropical Medicine & Parasitology (AREA)
  • Cell Biology (AREA)
  • Immunology (AREA)
  • Peptides Or Proteins (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
AU57376/96A 1995-05-08 1996-05-08 Nucleic acids for treating obesity Abandoned AU5737696A (en)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US437834 1989-11-16
US43783495A 1995-05-08 1995-05-08
PCT/US1996/006609 WO1996035787A1 (en) 1995-05-08 1996-05-08 Nucleic acids for treating obesity

Publications (1)

Publication Number Publication Date
AU5737696A true AU5737696A (en) 1996-11-29

Family

ID=23738095

Family Applications (1)

Application Number Title Priority Date Filing Date
AU57376/96A Abandoned AU5737696A (en) 1995-05-08 1996-05-08 Nucleic acids for treating obesity

Country Status (5)

Country Link
EP (1) EP0826045A1 (en)
JP (1) JP2000507081A (en)
AU (1) AU5737696A (en)
CA (1) CA2218529A1 (en)
WO (1) WO1996035787A1 (en)

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
AU743161B2 (en) * 1996-06-04 2002-01-17 Scripps Research Institute, The Diagnostic and therapeutic methods related to regulating energy mobilization with OB protein and OB antibodies

Families Citing this family (27)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6429290B1 (en) 1994-08-17 2002-08-06 The Rockefeller University OB polypeptides, modified forms and derivatives
US6001968A (en) 1994-08-17 1999-12-14 The Rockefeller University OB polypeptides, modified forms and compositions
GB9511935D0 (en) * 1995-06-13 1995-08-09 Smithkline Beecham Plc Novel compound
US6482927B1 (en) * 1995-11-27 2002-11-19 Millennium Pharmaceuticals, Inc. Chimeric proteins comprising the extracellular domain of murine Ob receptor
US20050019325A1 (en) 1996-01-08 2005-01-27 Carter Paul J. WSX receptor agonist antibodies
US7074397B1 (en) 1996-01-08 2006-07-11 Genentech, Inc. Method for enhancing proliferation or differentiation of a cell using ob protein
CA2241564C (en) * 1996-01-08 2013-09-03 Genentech, Inc. Wsx receptor and ligands
US7148004B1 (en) 1997-01-16 2006-12-12 The Rockefeller University Oligonucleotides of the OB-R isoforms and methods of diagnosing body weight
US7084252B1 (en) 1996-01-16 2006-08-01 The Rockefeller University DB, the receptor for leptin
US7063958B1 (en) * 1996-01-16 2006-06-20 The Rockefeller University Nucleic acids db, the receptor for leptin
AU2246097A (en) * 1996-01-25 1997-08-20 Eli Lilly And Company Obesity protein analog compounds and formulations thereof
US7619079B2 (en) 1996-02-14 2009-11-17 The Rockefeller University Db, the receptor for leptin, nucleic acids encoding the receptor, and uses thereof
US6281346B1 (en) 1996-03-22 2001-08-28 Merck & Co., Inc. Rat ob-receptors and nucleotides encoding them
US6258944B1 (en) 1996-05-06 2001-07-10 Merck & Co., Inc. OB receptor isoforms and nucleic acids encoding them
US7067472B1 (en) 1996-06-04 2006-06-27 The Scripps Research Institute Diagnostic and therapeutic methods related to regulating energy mobilization with OB protein and OB antibodies
JP2000514422A (en) * 1996-06-20 2000-10-31 メルク エンド カンパニー インコーポレーテッド Gene therapy for obesity
WO1997048806A1 (en) * 1996-06-20 1997-12-24 Merck & Co., Inc. Gene therapy for obesity
US6001816A (en) * 1996-06-20 1999-12-14 Merck & Co., Inc. Gene therapy for leptin deficiency
JP2001505437A (en) 1996-12-02 2001-04-24 メルク エンド カンパニー インコーポレーテッド Mutant OB receptor and nucleotides encoding it
CA2281888A1 (en) * 1997-02-25 1998-08-27 Eli Lilly And Company Treatment of infertility with leptin receptor ligands
US6420339B1 (en) 1998-10-14 2002-07-16 Amgen Inc. Site-directed dual pegylation of proteins for improved bioactivity and biocompatibility
ATA162699A (en) * 1999-09-23 2002-08-15 Vitateq Biotechnology Gmbh METHOD FOR DETERMINING THE FERTILITY OF MAMMALS, ESPECIALLY PEOPLE
AU7699900A (en) * 1999-10-01 2001-05-10 Eli Lilly And Company A novel human leptin homolog
DE60237100D1 (en) 2001-10-22 2010-09-02 Amgen Inc USE OF LEPTIN FOR THE TREATMENT OF LIPOATROPR PREDICTIVE POSITION AGAINST TREATMENT
US7629315B2 (en) 2005-03-09 2009-12-08 University Of Pittsburgh Of The Commonwealth System Of Higher Education Compositions for blocking the inhibitory effect of human CRP on human leptin
JP2012523434A (en) 2009-04-10 2012-10-04 アミリン・ファーマシューティカルズ，インコーポレイテッド Amylin agonist compounds for estrogen-deficient mammals
BR112013007388B1 (en) 2010-09-28 2022-01-04 Amylin Pharmaceuticals, Llc POLYPEPTIDE HAVING ALBUMIN AND LEPTIN BINDING DOMAIN, ITS USE IN THE TREATMENT OF DISEASES, AS WELL AS A PHARMACEUTICAL COMPOSITION THAT COMPRISES IT

Family Cites Families (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6309853B1 (en) * 1994-08-17 2001-10-30 The Rockfeller University Modulators of body weight, corresponding nucleic acids and proteins, and diagnostic and therapeutic uses thereof

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
AU743161B2 (en) * 1996-06-04 2002-01-17 Scripps Research Institute, The Diagnostic and therapeutic methods related to regulating energy mobilization with OB protein and OB antibodies

Also Published As

Publication number Publication date
JP2000507081A (en) 2000-06-13
CA2218529A1 (en) 1996-11-14
WO1996035787A1 (en) 1996-11-14
EP0826045A1 (en) 1998-03-04

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