AU5557300A - Bafilomycin derivatives with anticancer activity - Google Patents

Bafilomycin derivatives with anticancer activity

Info

Publication number
AU5557300A
AU5557300A AU55573/00A AU5557300A AU5557300A AU 5557300 A AU5557300 A AU 5557300A AU 55573/00 A AU55573/00 A AU 55573/00A AU 5557300 A AU5557300 A AU 5557300A AU 5557300 A AU5557300 A AU 5557300A
Authority
AU
Australia
Prior art keywords
anticancer activity
bafilomycin
derivatives
bafilomycin derivatives
anticancer
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Abandoned
Application number
AU55573/00A
Inventor
Librada Maria Canedo
Fernando Espliego
Luis Francisco Garcia
Dolores Garcia-Gravalos
Alberto Munoz
Francisco Romero
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Instituto Biomar SA
Original Assignee
Instituto Biomar SA
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Instituto Biomar SA filed Critical Instituto Biomar SA
Publication of AU5557300A publication Critical patent/AU5557300A/en
Abandoned legal-status Critical Current

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/70—Carbohydrates; Sugars; Derivatives thereof
    • A61K31/7042—Compounds having saccharide radicals and heterocyclic rings
    • A61K31/7048—Compounds having saccharide radicals and heterocyclic rings having oxygen as a ring hetero atom, e.g. leucoglucosan, hesperidin, erythromycin, nystatin, digitoxin or digoxin
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/335—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin
    • A61K31/365—Lactones
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A61P35/04—Antineoplastic agents specific for metastasis
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D313/00—Heterocyclic compounds containing rings of more than six members having one oxygen atom as the only ring hetero atom
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D407/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having oxygen atoms as the only ring hetero atoms, not provided for by group C07D405/00
    • C07D407/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having oxygen atoms as the only ring hetero atoms, not provided for by group C07D405/00 containing two hetero rings
    • C07D407/06—Heterocyclic compounds containing two or more hetero rings, at least one ring having oxygen atoms as the only ring hetero atoms, not provided for by group C07D405/00 containing two hetero rings linked by a carbon chain containing only aliphatic carbon atoms
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
    • C07H17/00—Compounds containing heterocyclic radicals directly attached to hetero atoms of saccharide radicals
    • C07H17/04—Heterocyclic radicals containing only oxygen as ring hetero atoms
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
    • C12P19/00—Preparation of compounds containing saccharide radicals
    • C12P19/44—Preparation of O-glycosides, e.g. glucosides
    • C12P19/58—Preparation of O-glycosides, e.g. glucosides having an oxygen atom of the saccharide radical directly bound through only acyclic carbon atoms to a non-saccharide heterocyclic ring, e.g. bleomycin, phleomycin

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Engineering & Computer Science (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Animal Behavior & Ethology (AREA)
  • Medicinal Chemistry (AREA)
  • Epidemiology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Biotechnology (AREA)
  • Biochemistry (AREA)
  • Zoology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Molecular Biology (AREA)
  • Wood Science & Technology (AREA)
  • Microbiology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Oncology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • General Engineering & Computer Science (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
AU55573/00A 1999-06-30 2000-06-30 Bafilomycin derivatives with anticancer activity Abandoned AU5557300A (en)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
GBGB9915306.6A GB9915306D0 (en) 1999-06-30 1999-06-30 New macrolide compounds,new use of known and new macrolides
GB9915306 1999-06-30
PCT/GB2000/002511 WO2001002413A1 (en) 1999-06-30 2000-06-30 BAFIlOMYCIN DERIVATIVES WITH ANTICANCER ACTIVITY

Publications (1)

Publication Number Publication Date
AU5557300A true AU5557300A (en) 2001-01-22

Family

ID=10856354

Family Applications (1)

Application Number Title Priority Date Filing Date
AU55573/00A Abandoned AU5557300A (en) 1999-06-30 2000-06-30 Bafilomycin derivatives with anticancer activity

Country Status (3)

Country Link
AU (1) AU5557300A (en)
GB (1) GB9915306D0 (en)
WO (1) WO2001002413A1 (en)

Families Citing this family (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
AU2003251730B2 (en) * 2002-07-02 2009-04-30 Janssen Pharmaceutica N.V. Bafilomycin-like metabolite from a novel Micromonospora species
EP1718631A4 (en) 2004-02-17 2009-04-15 Univ South Florida Cytotoxin compound and method of isolation
US8669376B2 (en) 2004-02-17 2014-03-11 University Of South Florida Cytotoxin compounds and methods of isolation

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS625990A (en) * 1985-06-20 1987-01-12 Sumitomo Chem Co Ltd Antibiotic substance and production thereof
US5324720A (en) * 1992-03-20 1994-06-28 Merck & Co., Inc. Methods of achieving antitumor activity using 16-membered-macrolide-type compounds
US5306716A (en) * 1992-03-20 1994-04-26 Merck & Co., Inc. Methods of achieving antileukemia activity using 16-membered-macrolide-type compounds
JPH09301991A (en) * 1996-05-14 1997-11-25 Mercian Corp Cancer metastasis inhibitor

Also Published As

Publication number Publication date
GB9915306D0 (en) 1999-09-01
WO2001002413A1 (en) 2001-01-11

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Legal Events

Date Code Title Description
MK6 Application lapsed section 142(2)(f)/reg. 8.3(3) - pct applic. not entering national phase