AU5432796A - Tricyclic compounds useful for inhibition of g-protein funct ion and for treatment of proliferative diseases - Google Patents

Tricyclic compounds useful for inhibition of g-protein funct ion and for treatment of proliferative diseases

Info

Publication number
AU5432796A
AU5432796A AU54327/96A AU5432796A AU5432796A AU 5432796 A AU5432796 A AU 5432796A AU 54327/96 A AU54327/96 A AU 54327/96A AU 5432796 A AU5432796 A AU 5432796A AU 5432796 A AU5432796 A AU 5432796A
Authority
AU
Australia
Prior art keywords
inhibition
protein
treatment
compounds useful
proliferative diseases
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Abandoned
Application number
AU54327/96A
Inventor
John J. Baldwin
Ge Li
John C Reader
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Pharmacopeia LLC
Original Assignee
Pharmacopeia Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Pharmacopeia Inc filed Critical Pharmacopeia Inc
Publication of AU5432796A publication Critical patent/AU5432796A/en
Abandoned legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
    • C07D401/14—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing three or more hetero rings

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
AU54327/96A 1995-04-07 1996-04-03 Tricyclic compounds useful for inhibition of g-protein funct ion and for treatment of proliferative diseases Abandoned AU5432796A (en)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US41898095A 1995-04-07 1995-04-07
US418980 1995-04-07
PCT/US1996/004170 WO1996031505A1 (en) 1995-04-07 1996-04-03 Tricyclic compounds useful for inhibition of g-protein function and for treatment of proliferative diseases

Publications (1)

Publication Number Publication Date
AU5432796A true AU5432796A (en) 1996-10-23

Family

ID=23660310

Family Applications (1)

Application Number Title Priority Date Filing Date
AU54327/96A Abandoned AU5432796A (en) 1995-04-07 1996-04-03 Tricyclic compounds useful for inhibition of g-protein funct ion and for treatment of proliferative diseases

Country Status (3)

Country Link
AU (1) AU5432796A (en)
IL (1) IL117797A0 (en)
WO (1) WO1996031505A1 (en)

Families Citing this family (13)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6117641A (en) 1996-04-11 2000-09-12 Mitotix, Inc. Assays and reagents for identifying anti-fungal agents and uses related thereto
EP0892854B1 (en) 1996-04-11 2002-07-03 Mitotix, Inc. Assays and reagents for identifying anti-fungal agents, and uses related thereto
US6727082B1 (en) 1996-04-11 2004-04-27 Gpc Biotech Inc. Assays and reagents for identifying anti-fungal agents, and uses related thereto
US5925639A (en) * 1997-06-17 1999-07-20 Schering Corporation Keto amide derivatives useful as farnesyl protein transferase inhibitors
US6426352B1 (en) 1997-06-17 2002-07-30 Schering Corporation Sulfonamide inhibitors of farnesyl-protein transferase
EP0989983B1 (en) * 1997-06-17 2004-08-11 Schering Corporation Benzpyrido cycloheptane compounds useful for inhibition of farnesyl protein transferase
US6225322B1 (en) 1997-06-17 2001-05-01 Schering Corporation Compounds useful for inhibition of farnesyl protein transferase
HUP0004627A2 (en) * 1997-06-17 2001-10-28 Schering Corp. Novel tricyclic sulfonamide inhibitors of farnesyl-protein transferase and medicaments containing the compounds
WO1998057964A1 (en) * 1997-06-17 1998-12-23 Schering Corporation Tricyclic compounds useful for inhibition of g-protein function and for treatment of proliferative diseases
US6242493B1 (en) 1998-03-13 2001-06-05 Merck Frosst Canada & Co. Carboxylic acids and acylsulfonamides, compositions containing such compounds and methods of treatment
WO1999047497A2 (en) * 1998-03-13 1999-09-23 Merck Frosst Canada & Co. Carboxylic acids and acylsulfonamides, compositions containing such compounds and methods of treatment
US6372747B1 (en) 1998-12-18 2002-04-16 Schering Corporation Farnesyl protein transferase inhibitors
EP1656156A2 (en) 2003-08-13 2006-05-17 Children's Hospital Medical Center Mobilization of hematopoietic cells

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE69120430D1 (en) * 1990-12-18 1996-07-25 Wellcome Found AGENTS FOR REINFORCING THE EFFECT OF ANTITUMORAL AGENTS AND FOR RESISTANCE TO MULTIPLE DRUGS
AU675145B2 (en) * 1993-06-18 1997-01-23 Merck & Co., Inc. Inhibitors of farnesyl-protein transferase
WO1995010515A1 (en) * 1993-10-15 1995-04-20 Schering Corporation Tricyclic carbamate compounds useful for inhibition of g-protein function and for treatment of proliferative diseases
SG43768A1 (en) * 1993-10-15 1997-11-14 Schering Corp Tricyclic sulfonamide compounds useful for inhibition of g-protein function and for treatment of proliferative dieases
IL111235A (en) * 1993-10-15 2001-03-19 Schering Plough Corp Pharmaceutical compositions for inhibition of g-protein function and for treatment of proliferative diseases containing tricyclic compounds some such compounds and process for preparing part of them

Also Published As

Publication number Publication date
WO1996031505A1 (en) 1996-10-10
IL117797A0 (en) 1996-08-04

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