AU5411499A - Piperazinone derivatives - Google Patents

Piperazinone derivatives

Info

Publication number
AU5411499A
AU5411499A AU54114/99A AU5411499A AU5411499A AU 5411499 A AU5411499 A AU 5411499A AU 54114/99 A AU54114/99 A AU 54114/99A AU 5411499 A AU5411499 A AU 5411499A AU 5411499 A AU5411499 A AU 5411499A
Authority
AU
Australia
Prior art keywords
piperazinone derivatives
piperazinone
derivatives
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Abandoned
Application number
AU54114/99A
Inventor
Sabine Bernotat-Danielowski
Hans-Peter Dr Buchstaller
Dieter Dorsch
Horst Juraszyk
Werner Mederski
Guido Melzer
Hanns Wurziger
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Merck Patent GmbH
Original Assignee
Merck Patent GmbH
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Merck Patent GmbH filed Critical Merck Patent GmbH
Publication of AU5411499A publication Critical patent/AU5411499A/en
Abandoned legal-status Critical Current

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D413/00Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms
    • C07D413/02Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings
    • C07D413/10Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings linked by a carbon chain containing aromatic rings
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P7/00Drugs for disorders of the blood or the extracellular fluid
    • A61P7/02Antithrombotic agents; Anticoagulants; Platelet aggregation inhibitors
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00Drugs for disorders of the cardiovascular system
    • A61P9/10Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D241/00Heterocyclic compounds containing 1,4-diazine or hydrogenated 1,4-diazine rings
    • C07D241/02Heterocyclic compounds containing 1,4-diazine or hydrogenated 1,4-diazine rings not condensed with other rings
    • C07D241/06Heterocyclic compounds containing 1,4-diazine or hydrogenated 1,4-diazine rings not condensed with other rings having one or two double bonds between ring members or between ring members and non-ring members
    • C07D241/08Heterocyclic compounds containing 1,4-diazine or hydrogenated 1,4-diazine rings not condensed with other rings having one or two double bonds between ring members or between ring members and non-ring members with oxygen atoms directly attached to ring carbon atoms

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Animal Behavior & Ethology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Public Health (AREA)
  • Pharmacology & Pharmacy (AREA)
  • General Health & Medical Sciences (AREA)
  • Urology & Nephrology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Vascular Medicine (AREA)
  • Cardiology (AREA)
  • Diabetes (AREA)
  • Hematology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
AU54114/99A 1998-08-08 1999-07-16 Piperazinone derivatives Abandoned AU5411499A (en)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
DE19835950A DE19835950A1 (en) 1998-08-08 1998-08-08 Piperazinone derivatives
DE19835950 1998-08-08
PCT/EP1999/005070 WO2000008005A2 (en) 1998-08-08 1999-07-16 Piperazinone derivatives

Publications (1)

Publication Number Publication Date
AU5411499A true AU5411499A (en) 2000-02-28

Family

ID=7876912

Family Applications (1)

Application Number Title Priority Date Filing Date
AU54114/99A Abandoned AU5411499A (en) 1998-08-08 1999-07-16 Piperazinone derivatives

Country Status (4)

Country Link
AR (1) AR020124A1 (en)
AU (1) AU5411499A (en)
DE (1) DE19835950A1 (en)
WO (1) WO2000008005A2 (en)

Families Citing this family (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP1051176B1 (en) * 1998-01-27 2006-11-22 Aventis Pharmaceuticals Inc. SUBSTITUTED OXOAZAHETEROCYCLYL FACTOR Xa INHIBITORS
EP1322643A1 (en) * 2000-09-29 2003-07-02 Millennium Pharmaceuticals, Inc. Piperazin-2-one amides as inhibitors of factor xa
AU2003282566A1 (en) * 2002-10-09 2004-05-04 Millennium Pharmaceuticals, Inc. Piperazine and piperazinone inhibitors of factor xa
PT1569912E (en) 2002-12-03 2015-09-15 Pharmacyclics Llc 2-(2-hydroxybiphenyl-3-yl)-1h-benzoimidazole-5-carboxamidine derivatives as factor viia inhibitors

Family Cites Families (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE4302485A1 (en) * 1993-01-29 1994-08-04 Merck Patent Gmbh Piperazine derivatives
ES2134870T3 (en) * 1993-05-01 1999-10-16 Merck Patent Gmbh ADHESION RECEPTOR ANTAGONISTS.
IL115420A0 (en) * 1994-09-26 1995-12-31 Zeneca Ltd Aminoheterocyclic derivatives
DE19530996A1 (en) * 1995-08-23 1997-02-27 Boehringer Mannheim Gmbh Cyclic guanidines, process for their preparation and pharmaceuticals
EP0765660A3 (en) * 1995-09-28 1998-09-23 Takeda Chemical Industries, Ltd. Microcapsules comprising 2-piperazinone-1-acetic acid compounds
AU4172397A (en) * 1996-09-06 1998-03-26 Biochem Pharma Inc. Lactam inhibitors of thrombin

Also Published As

Publication number Publication date
WO2000008005A3 (en) 2000-05-18
AR020124A1 (en) 2002-04-10
WO2000008005A2 (en) 2000-02-17
DE19835950A1 (en) 2000-02-10

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Legal Events

Date Code Title Description
MK6 Application lapsed section 142(2)(f)/reg. 8.3(3) - pct applic. not entering national phase