AU5341699A - Antiproliferative naphthoquinones, derivatives, compositions, and uses thereof - Google Patents

Antiproliferative naphthoquinones, derivatives, compositions, and uses thereof

Info

Publication number
AU5341699A
AU5341699A AU53416/99A AU5341699A AU5341699A AU 5341699 A AU5341699 A AU 5341699A AU 53416/99 A AU53416/99 A AU 53416/99A AU 5341699 A AU5341699 A AU 5341699A AU 5341699 A AU5341699 A AU 5341699A
Authority
AU
Australia
Prior art keywords
naphthoquinones
antiproliferative
derivatives
compositions
antiproliferative naphthoquinones
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Abandoned
Application number
AU53416/99A
Inventor
Brian I. Carr
Jeffrey K. Kerns
Craig S. Wilcox
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
University of Pittsburgh
Original Assignee
University of Pittsburgh
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by University of Pittsburgh filed Critical University of Pittsburgh
Publication of AU5341699A publication Critical patent/AU5341699A/en
Abandoned legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C323/00—Thiols, sulfides, hydropolysulfides or polysulfides substituted by halogen, oxygen or nitrogen atoms, or by sulfur atoms not being part of thio groups
    • C07C323/22—Thiols, sulfides, hydropolysulfides or polysulfides substituted by halogen, oxygen or nitrogen atoms, or by sulfur atoms not being part of thio groups containing thio groups and doubly-bound oxygen atoms bound to the same carbon skeleton
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C205/00—Compounds containing nitro groups bound to a carbon skeleton
    • C07C205/45—Compounds containing nitro groups bound to a carbon skeleton the carbon skeleton being further substituted by at least one doubly—bound oxygen atom, not being part of a —CHO group
    • C07C205/46—Compounds containing nitro groups bound to a carbon skeleton the carbon skeleton being further substituted by at least one doubly—bound oxygen atom, not being part of a —CHO group the carbon skeleton containing carbon atoms of quinone rings
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C233/00—Carboxylic acid amides
    • C07C233/01—Carboxylic acid amides having carbon atoms of carboxamide groups bound to hydrogen atoms or to acyclic carbon atoms
    • C07C233/30—Carboxylic acid amides having carbon atoms of carboxamide groups bound to hydrogen atoms or to acyclic carbon atoms having the nitrogen atom of at least one of the carboxamide groups bound to a carbon atom of a hydrocarbon radical substituted by doubly-bound oxygen atoms
    • C07C233/33—Carboxylic acid amides having carbon atoms of carboxamide groups bound to hydrogen atoms or to acyclic carbon atoms having the nitrogen atom of at least one of the carboxamide groups bound to a carbon atom of a hydrocarbon radical substituted by doubly-bound oxygen atoms with the substituted hydrocarbon radical bound to the nitrogen atom of the carboxamide group by a carbon atom of a six-membered aromatic ring
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C43/00—Ethers; Compounds having groups, groups or groups
    • C07C43/02—Ethers
    • C07C43/20—Ethers having an ether-oxygen atom bound to a carbon atom of a six-membered aromatic ring
    • C07C43/225—Ethers having an ether-oxygen atom bound to a carbon atom of a six-membered aromatic ring containing halogen
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C46/00—Preparation of quinones
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C46/00—Preparation of quinones
    • C07C46/02—Preparation of quinones by oxidation giving rise to quinoid structures
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C50/00—Quinones
    • C07C50/24—Quinones containing halogen
AU53416/99A 1998-08-06 1999-08-06 Antiproliferative naphthoquinones, derivatives, compositions, and uses thereof Abandoned AU5341699A (en)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US12993298A 1998-08-06 1998-08-06
US09129932 1998-08-06
PCT/US1999/017863 WO2000008495A2 (en) 1998-08-06 1999-08-06 Antiproliferative naphthoquinones, derivatives, compositions, and uses thereof

Publications (1)

Publication Number Publication Date
AU5341699A true AU5341699A (en) 2000-02-28

Family

ID=22442272

Family Applications (1)

Application Number Title Priority Date Filing Date
AU53416/99A Abandoned AU5341699A (en) 1998-08-06 1999-08-06 Antiproliferative naphthoquinones, derivatives, compositions, and uses thereof

Country Status (2)

Country Link
AU (1) AU5341699A (en)
WO (1) WO2000008495A2 (en)

Families Citing this family (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP2093207A1 (en) * 2008-02-06 2009-08-26 Julius-Maximilians-Universität Würzburg Antiinfective and antitumoral compounds isolated from tropical lianas
AT509501B1 (en) 2010-02-24 2012-06-15 Univ Wien Tech PESTICIDES
US9422231B2 (en) 2011-07-27 2016-08-23 Howard University Method for inhibiting Trypanosoma cruzi
EP2671574A1 (en) * 2012-06-04 2013-12-11 VitaK B.V. Use of vitamin K to decrease allograft failure and patient mortality after organ transplantation
RU2499789C1 (en) * 2012-11-01 2013-11-27 Федеральное государственное бюджетное учреждение науки Институт химической биологии и фундаментальной медицины Сибирского отделения Российской академии наук (ИХБФМ СО РАН) Alkylating fluorinated 1,4-naphthoquinone derivatives having cytotoxic effect on human cancer cells in culture
US10934253B2 (en) 2017-04-21 2021-03-02 University Of Tasmania Therapeutic compounds and methods
CN107793380B (en) * 2017-10-30 2021-04-23 黑龙江八一农垦大学 2, 3-epoxy-2-propyl sulfone-5, 8-dimethoxy-1, 4-naphthoquinone, preparation method thereof and medicine containing same
CN107759538B (en) * 2017-10-30 2021-04-23 黑龙江八一农垦大学 2, 3-epoxy-2-nonane sulfone-5, 8-dimethoxy-1, 4-naphthoquinone, preparation method thereof and medicine containing same

Family Cites Families (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
LU84511A1 (en) * 1982-12-08 1984-10-22 Oreal USE OF 5-HYDROXYNAPHTOQUINONES FOR THE DYEING OF HUMAN KERATINIC FIBERS, DYEING METHOD USING THE SAME AND TINCTORIAL COMPOSITION USED
ATE36316T1 (en) * 1984-01-27 1988-08-15 Syntex Inc NAPHTHALINE COMPOUNDS ACTIVE AGAINST PSORIASIS.
US4686220A (en) * 1985-12-19 1987-08-11 American Cyanamid Company Substituted 2-[b-substituted-amino)-ethylamino]-1,4-naphthalenediones for treating asthma, allergic diseases and inflammation in warm-blooded animals
FI881065A (en) * 1987-03-09 1988-09-10 Syntex Inc FOERFARANDE FOER FRAMSTAELLNING AV NAFTALENFOERENINGAR ANVAENDBARA VID BEHANDLING AV PSORIASIS.
US5089657A (en) * 1987-03-11 1992-02-18 Syntex (U.S.A.) Inc. Naphthalene anti-psoriatic agents
DE3801743A1 (en) * 1987-07-03 1989-01-19 Bayer Ag PEST CONTROLS BASED ON SUBSTITUTED 1,4-NAPHTHOCHINONS AND NEW SUBSTITUTED 1,4-NAPHTHOCHINONES
US5405598A (en) * 1992-02-24 1995-04-11 Schinazi; Raymond F. Sensitizing agents for use in boron neutron capture therapy
FR2757386B1 (en) * 1996-12-23 1999-01-29 Oreal TWO-STAGE OXIDATION DYEING PROCESS FOR KERATINIC FIBERS WITH MANGANESE SALT OR COMPLEX AND A 4-SUBSTITUTED 1-NAPHTOL AND DYEING KIT

Also Published As

Publication number Publication date
WO2000008495A2 (en) 2000-02-17
WO2000008495A3 (en) 2000-05-25

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Legal Events

Date Code Title Description
MK6 Application lapsed section 142(2)(f)/reg. 8.3(3) - pct applic. not entering national phase