AU5331199A - Method for the production of an antibiotic agent - Google Patents

Method for the production of an antibiotic agent

Info

Publication number
AU5331199A
AU5331199A AU53311/99A AU5331199A AU5331199A AU 5331199 A AU5331199 A AU 5331199A AU 53311/99 A AU53311/99 A AU 53311/99A AU 5331199 A AU5331199 A AU 5331199A AU 5331199 A AU5331199 A AU 5331199A
Authority
AU
Australia
Prior art keywords
production
antibiotic agent
antibiotic
agent
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Abandoned
Application number
AU53311/99A
Inventor
Neal C. Connors
Lisa M. Dimichele
David L. Hughes
Thomas J. Novak
Leslie A. Petersen
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Merck and Co Inc
Original Assignee
Merck and Co Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Merck and Co Inc filed Critical Merck and Co Inc
Publication of AU5331199A publication Critical patent/AU5331199A/en
Abandoned legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K7/00—Peptides having 5 to 20 amino acids in a fully defined sequence; Derivatives thereof
    • C07K7/50—Cyclic peptides containing at least one abnormal peptide link
    • C07K7/54—Cyclic peptides containing at least one abnormal peptide link with at least one abnormal peptide link in the ring
    • C07K7/56—Cyclic peptides containing at least one abnormal peptide link with at least one abnormal peptide link in the ring the cyclisation not occurring through 2,4-diamino-butanoic acid
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04—Antibacterial agents
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
    • C12P21/00—Preparation of peptides or proteins

Landscapes

  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • General Chemical & Material Sciences (AREA)
  • Biochemistry (AREA)
  • Medicinal Chemistry (AREA)
  • Molecular Biology (AREA)
  • Zoology (AREA)
  • Wood Science & Technology (AREA)
  • Engineering & Computer Science (AREA)
  • Genetics & Genomics (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Oncology (AREA)
  • Biotechnology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Communicable Diseases (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Microbiology (AREA)
  • Biophysics (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • General Engineering & Computer Science (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Peptides Or Proteins (AREA)
AU53311/99A 1998-08-07 1999-08-04 Method for the production of an antibiotic agent Abandoned AU5331199A (en)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US9569198P 1998-08-07 1998-08-07
US60095691 1998-08-07
PCT/US1999/017444 WO2000008197A1 (en) 1998-08-07 1999-08-04 Method for the production of an antibiotic agent

Publications (1)

Publication Number Publication Date
AU5331199A true AU5331199A (en) 2000-02-28

Family

ID=22253174

Family Applications (1)

Application Number Title Priority Date Filing Date
AU53311/99A Abandoned AU5331199A (en) 1998-08-07 1999-08-04 Method for the production of an antibiotic agent

Country Status (4)

Country Link
EP (1) EP1100947A4 (en)
JP (1) JP2003510245A (en)
AU (1) AU5331199A (en)
WO (1) WO2000008197A1 (en)

Families Citing this family (11)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6696412B1 (en) 2000-01-20 2004-02-24 Cubist Pharmaceuticals, Inc. High purity lipopeptides, Lipopeptide micelles and processes for preparing same
NZ571597A (en) 2000-12-18 2010-05-28 Cubist Pharm Inc Method for preparing crystalline and crystal-like forms of purified daptomycin lipopeptides
WO2009158034A1 (en) * 2008-06-25 2009-12-30 Teva Gyogyszergyar Zartkoruen Mukodo Reszvenytarsasag Caspofungin free of caspofungin impurity a
CN101928670B (en) * 2009-09-24 2012-02-22 上海天伟生物制药有限公司 High-yield bacterial strain of antibiotic, preparation method and usage thereof
SI2552941T1 (en) 2010-03-29 2016-11-30 Dsm Sinochem Pharmaceuticals Netherlands B.V. Purification of caspofungin intermediates
US20140349345A1 (en) 2012-01-13 2014-11-27 Dsm Sinochem Pharmaceuticals Netherlands B.V. Cyclopeptide fermentation at increased metal ion concentration
CN112110991A (en) * 2014-12-24 2020-12-22 上海天伟生物制药有限公司 Composition containing nitrogen heterocyclic hexapeptide precursor and preparation method and application thereof
CN106755223A (en) * 2017-01-20 2017-05-31 信泰制药（苏州）有限公司 A kind of fermentation process of Pneumocandin B0
CN107201316B (en) * 2017-07-14 2020-04-07 海正药业(杭州)有限公司 Aspergillus and producing pneumocandin B thereof0Method (2)
CN113046250B (en) * 2019-12-27 2023-01-24 上海医药工业研究院 Production of pneumocandin B 0 Genetically engineered bacterium, and preparation method and application thereof
CN113046251B (en) * 2019-12-27 2023-01-24 上海医药工业研究院 Production of pneumocandin B 0 The gene engineering bacterium, its preparation method and application

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4968608A (en) * 1987-10-07 1990-11-06 Merck & Co., Inc. Process for antifungal fermentation product
US4931352A (en) * 1987-10-07 1990-06-05 Merck & Co., Inc. Antifungal fermentation product
US5021341A (en) * 1990-03-12 1991-06-04 Merck & Co., Inc. Antibiotic agent produced by the cultivation of Zalerion microorganism in the presence of mannitol
US5049546A (en) * 1990-03-19 1991-09-17 Merck & Co., Inc. Antibiotic agents

Also Published As

Publication number Publication date
EP1100947A1 (en) 2001-05-23
JP2003510245A (en) 2003-03-18
EP1100947A4 (en) 2001-09-05
WO2000008197A1 (en) 2000-02-17

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Legal Events

Date Code Title Description
MK6 Application lapsed section 142(2)(f)/reg. 8.3(3) - pct applic. not entering national phase