AU5240501A - Pyrido' 1,2-alpha pyrazine and piperidine derivatives as ligands for the neuropeptide y y5 receptor - Google Patents
Pyrido' 1,2-alpha pyrazine and piperidine derivatives as ligands for the neuropeptide y y5 receptorInfo
- Publication number
- AU5240501A AU5240501A AU52405/01A AU5240501A AU5240501A AU 5240501 A AU5240501 A AU 5240501A AU 52405/01 A AU52405/01 A AU 52405/01A AU 5240501 A AU5240501 A AU 5240501A AU 5240501 A AU5240501 A AU 5240501A
- Authority
- AU
- Australia
- Prior art keywords
- neuropeptide
- pyrido
- pyrazine
- ligands
- receptor
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Abandoned
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
- C07D401/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
- C07D401/12—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings linked by a chain containing hetero atoms as chain links
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/04—Anorexiants; Antiobesity agents
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D471/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
- C07D471/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains two hetero rings
- C07D471/04—Ortho-condensed systems
Applications Claiming Priority (3)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
GB0011013 | 2000-05-09 | ||
GBGB0011013.0A GB0011013D0 (en) | 2000-05-09 | 2000-05-09 | Chemical compounds |
PCT/GB2001/001961 WO2001085730A1 (en) | 2000-05-09 | 2001-05-04 | Pyrido' 1,2-alpha pyrazine and piperidine derivatives as ligands for the neuropeptide y y5 receptor |
Publications (1)
Publication Number | Publication Date |
---|---|
AU5240501A true AU5240501A (en) | 2001-11-20 |
Family
ID=9891136
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
AU52405/01A Abandoned AU5240501A (en) | 2000-05-09 | 2001-05-04 | Pyrido' 1,2-alpha pyrazine and piperidine derivatives as ligands for the neuropeptide y y5 receptor |
Country Status (3)
Country | Link |
---|---|
AU (1) | AU5240501A (en) |
GB (1) | GB0011013D0 (en) |
WO (1) | WO2001085730A1 (en) |
Families Citing this family (54)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
GB0010757D0 (en) | 2000-05-05 | 2000-06-28 | Astrazeneca Ab | Chemical compounds |
GB0121941D0 (en) | 2001-09-11 | 2001-10-31 | Astrazeneca Ab | Chemical compounds |
US7105526B2 (en) | 2002-06-28 | 2006-09-12 | Banyu Pharmaceuticals Co., Ltd. | Benzimidazole derivatives |
US7772188B2 (en) | 2003-01-28 | 2010-08-10 | Ironwood Pharmaceuticals, Inc. | Methods and compositions for the treatment of gastrointestinal disorders |
EP1669350B1 (en) | 2003-09-22 | 2012-02-29 | Msd K.K. | Piperidine derivatives |
WO2005097127A2 (en) | 2004-04-02 | 2005-10-20 | Merck & Co., Inc. | Method of treating men with metabolic and anthropometric disorders |
WO2006052608A2 (en) | 2004-11-01 | 2006-05-18 | Amylin Pharmaceuticals, Inc. | Treatment of obesity and related disorders |
WO2007022123A2 (en) | 2005-08-11 | 2007-02-22 | Amylin Pharmaceuticals, Inc. | Hybrid polypeptides with selectable properties |
US7737155B2 (en) | 2005-05-17 | 2010-06-15 | Schering Corporation | Nitrogen-containing heterocyclic compounds and methods of use thereof |
KR101397913B1 (en) | 2005-05-30 | 2014-05-26 | 엠에스디 가부시키가이샤 | Novel piperidine derivative |
JPWO2007018248A1 (en) | 2005-08-10 | 2009-02-19 | 萬有製薬株式会社 | Pyridone compounds |
EP2330125A3 (en) | 2005-08-11 | 2012-12-12 | Amylin Pharmaceuticals, Inc. | Hybrid polypeptides with selectable properties |
EP1921065B1 (en) | 2005-08-24 | 2010-10-20 | Banyu Pharmaceutical Co., Ltd. | Phenylpyridone derivative |
CA2621470A1 (en) | 2005-09-07 | 2007-03-15 | Banyu Pharmaceutical Co., Ltd. | Bicyclic aromatic substituted pyridone derivative |
RU2008116844A (en) | 2005-09-29 | 2009-11-10 | Мерк энд Ко., Инк. (US) | Acylated Spiropiperidine Derivatives as Modulators of the Melanocortin-4 Receptor |
BRPI0617621A2 (en) | 2005-10-21 | 2011-08-02 | Novartis Ag | combination of organic compounds |
EP1944301A4 (en) | 2005-10-27 | 2012-01-04 | Msd Kk | Novel benzoxathiin derivative |
JP4371164B2 (en) | 2005-11-10 | 2009-11-25 | 萬有製薬株式会社 | Aza-substituted spiro derivatives |
AU2007300627B2 (en) | 2006-09-22 | 2012-02-16 | Merck Sharp & Dohme Corp. | Method of treatment using fatty acid synthesis inhibitors |
JPWO2008038692A1 (en) | 2006-09-28 | 2010-01-28 | 萬有製薬株式会社 | Diaryl ketimine derivatives |
AU2008233662B2 (en) | 2007-04-02 | 2012-08-23 | Msd K.K. | Indoledione derivative |
MX354786B (en) | 2007-06-04 | 2018-03-21 | Synergy Pharmaceuticals Inc | AGONISTS OF GUANYLATE CYCLASE USEFUL FOR THE TREATMENT OF GASTROINTESTINAL DISORDERS, INFLAMMATION, CANCER and OTHER DISORDERS. |
US8969514B2 (en) | 2007-06-04 | 2015-03-03 | Synergy Pharmaceuticals, Inc. | Agonists of guanylate cyclase useful for the treatment of hypercholesterolemia, atherosclerosis, coronary heart disease, gallstone, obesity and other cardiovascular diseases |
JPWO2009110510A1 (en) | 2008-03-06 | 2011-07-14 | Msd株式会社 | Alkylaminopyridine derivatives |
CA2717384A1 (en) | 2008-03-28 | 2009-10-01 | Banyu Pharmaceutical Co., Ltd. | Diarylmethylamide derivative having melanin-concentrating hormone receptor antagonism |
AU2009256157B2 (en) | 2008-06-04 | 2014-12-18 | Bausch Health Ireland Limited | Agonists of guanylate cyclase useful for the treatment of gastrointestinal disorders, inflammation, cancer and other disorders |
US20110071129A1 (en) | 2008-06-19 | 2011-03-24 | Makoto Ando | Spirodiamine-diaryl ketoxime derivative |
ES2624828T3 (en) | 2008-07-16 | 2017-07-17 | Synergy Pharmaceuticals Inc. | Guanylate cyclase agonists useful for the treatment of gastrointestinal disorders, inflammation, cancer and others |
WO2010013595A1 (en) | 2008-07-30 | 2010-02-04 | 萬有製薬株式会社 | (5-membered)-(5-membered) or (5-membered)-(6-membered) fused ring cycloalkylamine derivative |
CN102264228A (en) | 2008-10-22 | 2011-11-30 | 默沙东公司 | Novel cyclic benzimidazole derivatives useful for anti-diabetic agents |
KR101320245B1 (en) | 2008-10-30 | 2013-10-30 | 머크 샤프 앤드 돔 코포레이션 | Isonicotinamide orexin receptor antagonists |
US8329914B2 (en) | 2008-10-31 | 2012-12-11 | Merck Sharp & Dohme Corp | Cyclic benzimidazole derivatives useful as anti-diabetic agents |
US20110243940A1 (en) | 2008-12-16 | 2011-10-06 | Schering Corporation | Bicyclic pyranone derivatives and methods of use thereof |
US20110245209A1 (en) | 2008-12-16 | 2011-10-06 | Schering Corporation | Pyridopyrimidine derivatives and methods of use thereof |
JP2013520502A (en) | 2010-02-25 | 2013-06-06 | メルク・シャープ・エンド・ドーム・コーポレイション | Novel cyclic benzimidazole derivatives that are useful anti-diabetic drugs |
US9616097B2 (en) | 2010-09-15 | 2017-04-11 | Synergy Pharmaceuticals, Inc. | Formulations of guanylate cyclase C agonists and methods of use |
FR2970965A1 (en) * | 2011-01-31 | 2012-08-03 | Centre Nat Rech Scient | ANTI-ANGIOGENIC COMPOUNDS, PHARMACEUTICAL COMPOSITIONS COMPRISING SAME, AND USE THEREOF |
EP2677869B1 (en) | 2011-02-25 | 2017-11-08 | Merck Sharp & Dohme Corp. | Novel cyclic azabenzimidazole derivatives useful as anti-diabetic agents |
AR088352A1 (en) | 2011-10-19 | 2014-05-28 | Merck Sharp & Dohme | ANTAGONISTS OF THE RECEIVER OF 2-PIRIDILOXI-4-NITRILE OREXINE |
WO2014022528A1 (en) | 2012-08-02 | 2014-02-06 | Merck Sharp & Dohme Corp. | Antidiabetic tricyclic compounds |
EP2958562A4 (en) | 2013-02-22 | 2016-08-10 | Merck Sharp & Dohme | Antidiabetic bicyclic compounds |
EP2970119B1 (en) | 2013-03-14 | 2021-11-03 | Merck Sharp & Dohme Corp. | Novel indole derivatives useful as anti-diabetic agents |
CA2905438A1 (en) | 2013-03-15 | 2014-09-25 | Synergy Pharmaceuticals Inc. | Agonists of guanylate cyclase and their uses |
AU2014235209B2 (en) | 2013-03-15 | 2018-06-14 | Bausch Health Ireland Limited | Guanylate cyclase receptor agonists combined with other drugs |
CA2913737A1 (en) | 2013-06-05 | 2014-12-11 | Synergy Pharmaceuticals, Inc. | Ultra-pure agonists of guanylate cyclase c, method of making and using same |
WO2015051496A1 (en) | 2013-10-08 | 2015-04-16 | Merck Sharp & Dohme Corp. | Antidiabetic tricyclic compounds |
ES2901114T3 (en) | 2014-08-29 | 2022-03-21 | Tes Pharma S R L | Alpha-amino-beta-carboxymuconic acid semialdehyde decarboxylase inhibitors |
US20180134667A1 (en) | 2016-10-14 | 2018-05-17 | TES Pharma S.r.I. | Inhibitors of alpha-amino-beta-carboxymuconic acid semialdehyde decarboxylase |
WO2018106518A1 (en) | 2016-12-06 | 2018-06-14 | Merck Sharp & Dohme Corp. | Antidiabetic heterocyclic compounds |
WO2018118670A1 (en) | 2016-12-20 | 2018-06-28 | Merck Sharp & Dohme Corp. | Antidiabetic spirochroman compounds |
MX2021005904A (en) | 2018-11-20 | 2021-09-08 | Tes Pharma S R L | INHIBITORS OF a-AMINO-ß-CARBOXYMUCONIC ACID SEMIALDEHYDE DECARBOXYLASE. |
TW202045476A (en) | 2019-02-13 | 2020-12-16 | 美商默沙東藥廠 | 5-alkyl pyrrolidine orexin receptor agonists |
WO2021026047A1 (en) | 2019-08-08 | 2021-02-11 | Merck Sharp & Dohme Corp. | Heteroaryl pyrrolidine and piperidine orexin receptor agonists |
WO2022040070A1 (en) | 2020-08-18 | 2022-02-24 | Merck Sharp & Dohme Corp. | Bicycloheptane pyrrolidine orexin receptor agonists |
Family Cites Families (4)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
SI9520096A (en) * | 1994-09-30 | 1998-04-30 | Pfizer Inc. | 2,7-SUBSTITUTED OCTAHYDRO-1H-PYRIDO /1,2-a/PYRAZINE DERIVATIVES |
AU1328197A (en) * | 1995-12-01 | 1997-06-19 | Synaptic Pharmaceutical Corporation | Aryl sulfonamide and sulfamide derivatives and uses thereof |
RU2219167C2 (en) * | 1998-04-29 | 2003-12-20 | Орто-Макнейл Фармасьютикал, Инк. | N-substituted aminotetralines as ligands for receptor of y5 of neuropeptide y useful in treatment of obesity and other disorders |
DK1202986T3 (en) * | 1999-07-28 | 2006-02-20 | Ortho Mcneil Pharm Inc | Amine and amide derivatives as ligands for the neuropeptide Y-Y5 receptor useful in the treatment of obesity and other disorders |
-
2000
- 2000-05-09 GB GBGB0011013.0A patent/GB0011013D0/en not_active Ceased
-
2001
- 2001-05-04 WO PCT/GB2001/001961 patent/WO2001085730A1/en active Application Filing
- 2001-05-04 AU AU52405/01A patent/AU5240501A/en not_active Abandoned
Also Published As
Publication number | Publication date |
---|---|
GB0011013D0 (en) | 2000-06-28 |
WO2001085730A1 (en) | 2001-11-15 |
Similar Documents
Publication | Publication Date | Title |
---|---|---|
AU5240501A (en) | Pyrido' 1,2-alpha pyrazine and piperidine derivatives as ligands for the neuropeptide y y5 receptor | |
HK1039330A1 (en) | Piperidine derivatives useful as ccr5 antagonists. | |
GC0000108A (en) | 4-Amino substituted-2-substituted-1,2,3,4-tetrahy droquinolines. | |
MXPA03008525A (en) | Imidazo (1,2-a)-pyridine derivatives as mglur5 antagonists. | |
AU6000900A (en) | Carbazole derivatives and their use as neuropeptide y5 receptor ligands | |
MXPA03005648A (en) | Carbazole derivatives and their use as neuropeptide y5 receptor ligands. | |
HK1039930A1 (en) | Piperazine derivatives useful as ccr5 antagonists. | |
AU2001230026A1 (en) | 2,4-diaminothiazole derivatives | |
AU2001277032A1 (en) | 2-(4-pyridyl)amino-6-dialkoxyphenyl-pyrido(2,3-d)pyrimidin-7 ones | |
AU4802500A (en) | 2-aminoquinolinecarboxamides: neurokinin receptor ligands | |
AU2001269876A1 (en) | Heteroarylalkanoic acids as integrin receptor antagonists | |
GB2361235B (en) | 2,2,6,6 Diethyl-dimethyl-1-alkoxy-piperidine compounds and their corresponding 1-oxides | |
MXPA03006991A (en) | Piperidinee derivatives as neurokinin 1 antagonists. | |
AU6202500A (en) | Durable multilayer nonwoven materials | |
AU3819200A (en) | 2,4-diamino-pyrimidine derivatives | |
AU2001226794A1 (en) | Substituted 1,2,3,4- tetrahydroquinoline-2-carboxylic acid derivatives | |
ATE274899T1 (en) | MOUTH-DISCLOSING COMPOSITION CONTAINING MIRTAZAPINE | |
AU2673201A (en) | Alpha-arylethylpiperazine derivatives as neurokinin antagonists | |
AU5786300A (en) | Muscarinic antagonists | |
AU2002218400A1 (en) | 3-substituted 2,7-naphthyridin-1-yl derivatives | |
AU3076600A (en) | 3,7-disubstituted indole derivatives and medicinal compositions containing the same | |
AU2001264097A1 (en) | 1, 2, 3, 5 -tetrahydrobenzo`c!azepin-4-one derivatives having muscarinic antagonist activity | |
AU2001252254A1 (en) | 2,6-diamino-6-methyl-heptanoic acid and derivatives, process for the preparationthereof and use thereof | |
AU2631000A (en) | Plasticized composition | |
AU2002210526A1 (en) | Substituted 3.4-dihydro-pyrido[1,2-A]pyrimidines |
Legal Events
Date | Code | Title | Description |
---|---|---|---|
MK6 | Application lapsed section 142(2)(f)/reg. 8.3(3) - pct applic. not entering national phase |