AU5217100A - Adenoviral vectors encoding interferon and their use in gene therapy - Google Patents

Adenoviral vectors encoding interferon and their use in gene therapy

Info

Publication number
AU5217100A
AU5217100A AU52171/00A AU5217100A AU5217100A AU 5217100 A AU5217100 A AU 5217100A AU 52171/00 A AU52171/00 A AU 52171/00A AU 5217100 A AU5217100 A AU 5217100A AU 5217100 A AU5217100 A AU 5217100A
Authority
AU
Australia
Prior art keywords
gene therapy
adenoviral vectors
vectors encoding
encoding interferon
interferon
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Abandoned
Application number
AU52171/00A
Inventor
Gennaro Ciliberto
Nicola La Monica
Fabio Palombo
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Istituto di Ricerche di Biologia Molecolare P Angeletti SpA
Original Assignee
Istituto di Ricerche di Biologia Molecolare P Angeletti SpA
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Istituto di Ricerche di Biologia Molecolare P Angeletti SpA filed Critical Istituto di Ricerche di Biologia Molecolare P Angeletti SpA
Publication of AU5217100A publication Critical patent/AU5217100A/en
Abandoned legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09—Recombinant DNA-technology
    • C12N15/63—Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression
    • C12N15/79—Vectors or expression systems specially adapted for eukaryotic hosts
    • C12N15/85—Vectors or expression systems specially adapted for eukaryotic hosts for animal cells
    • C12N15/86—Viral vectors
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/52—Cytokines; Lymphokines; Interferons
    • C07K14/555—Interferons [IFN]
    • C07K14/56—IFN-alpha
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K48/00—Medicinal preparations containing genetic material which is inserted into cells of the living body to treat genetic diseases; Gene therapy
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2710/00—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA dsDNA viruses
    • C12N2710/00011—Details
    • C12N2710/10011—Adenoviridae
    • C12N2710/10311—Mastadenovirus, e.g. human or simian adenoviruses
    • C12N2710/10341—Use of virus, viral particle or viral elements as a vector
    • C12N2710/10343—Use of virus, viral particle or viral elements as a vector viral genome or elements thereof as genetic vector
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2830/00—Vector systems having a special element relevant for transcription
    • C12N2830/001—Vector systems having a special element relevant for transcription controllable enhancer/promoter combination
    • C12N2830/002—Vector systems having a special element relevant for transcription controllable enhancer/promoter combination inducible enhancer/promoter combination, e.g. hypoxia, iron, transcription factor
    • C12N2830/003—Vector systems having a special element relevant for transcription controllable enhancer/promoter combination inducible enhancer/promoter combination, e.g. hypoxia, iron, transcription factor tet inducible
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2830/00—Vector systems having a special element relevant for transcription
    • C12N2830/008—Vector systems having a special element relevant for transcription cell type or tissue specific enhancer/promoter combination
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2830/00—Vector systems having a special element relevant for transcription
    • C12N2830/38—Vector systems having a special element relevant for transcription being a stuffer
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2830/00—Vector systems having a special element relevant for transcription
    • C12N2830/42—Vector systems having a special element relevant for transcription being an intron or intervening sequence for splicing and/or stability of RNA

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Zoology (AREA)
  • Engineering & Computer Science (AREA)
  • Biotechnology (AREA)
  • General Health & Medical Sciences (AREA)
  • Biophysics (AREA)
  • Wood Science & Technology (AREA)
  • Molecular Biology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Biochemistry (AREA)
  • General Engineering & Computer Science (AREA)
  • Biomedical Technology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Physics & Mathematics (AREA)
  • Toxicology (AREA)
  • Virology (AREA)
  • Plant Pathology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Microbiology (AREA)
  • Medicinal Chemistry (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
AU52171/00A 1999-06-03 2000-05-29 Adenoviral vectors encoding interferon and their use in gene therapy Abandoned AU5217100A (en)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
GB9912925 1999-06-03
GBGB9912925.6A GB9912925D0 (en) 1999-06-03 1999-06-03 Adenoviral vectors encoding interferon and their use in gene therapy
PCT/EP2000/004875 WO2000075354A2 (en) 1999-06-03 2000-05-29 Adenoviral vectors encoding interferon and their use in gene therapy

Publications (1)

Publication Number Publication Date
AU5217100A true AU5217100A (en) 2000-12-28

Family

ID=10854684

Family Applications (1)

Application Number Title Priority Date Filing Date
AU52171/00A Abandoned AU5217100A (en) 1999-06-03 2000-05-29 Adenoviral vectors encoding interferon and their use in gene therapy

Country Status (3)

Country Link
AU (1) AU5217100A (en)
GB (1) GB9912925D0 (en)
WO (1) WO2000075354A2 (en)

Families Citing this family (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN1388248A (en) * 2001-05-25 2003-01-01 钱其军 Adenovirus proliferated specifically inside tumor cell to express interferon in high efficiency and its construction method

Family Cites Families (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
PL332856A1 (en) * 1996-10-18 1999-10-25 Canji Methods of and compositions for delivery and expression of nucleic acids as needed by interferon

Also Published As

Publication number Publication date
WO2000075354A3 (en) 2001-07-12
GB9912925D0 (en) 1999-08-04
WO2000075354A2 (en) 2000-12-14

Similar Documents

Publication Publication Date Title
ZA958686B (en) Viral vectors and use in gene therapy
AU3395900A (en) Human lung cancer associated gene sequences and polypeptides
GB9721909D0 (en) Gene delivery vectors and their uses
ZA945012B (en) Viral vectors and their use in gene therapy
AU2001257532A1 (en) Adenoviral vectors for tumor specific gene expression and uses thereof
IT1291135B1 (en) RECOMBINANT VECTORS USABLE IN GENE THERAPY
IL128193A0 (en) Rhamnosyl-transferase gene and uses thereof
GB9817660D0 (en) Adenoviral vectors encoding erythropoietin and their use in gene therapy
EP1117761A4 (en) Gene encoding mnr2 and uses thereof
AU1598599A (en) Anti-angiogenic gene therapy vectors and their use in treating angiogenesis-related diseases
IL112993A0 (en) Recombinant niruses, their preparation and their use in gene therapy
AU5217100A (en) Adenoviral vectors encoding interferon and their use in gene therapy
EP1241256A4 (en) Novel gene and use thereof
AU1926699A (en) Cathepsin dc proteins, dna encoding the proteins, and their use in human cancer prognosis
AU6149600A (en) Novel vector complexes and their use in gene therapy
AU3774499A (en) Adenoviral vector encoding anti-apoptotic bcl-2 gene and uses thereof
AU4293600A (en) Recombinant protein uk114 and its use in therapy and diagnostics
EP1116793A4 (en) Homeobox genes encoding proteins participating in differentiation
AU3698699A (en) Vectors and viruses used in gene therapy
AU5760200A (en) Human genes and proteins encoded thereby
AU2001234150A1 (en) Novel protein and gene encoding the same
AU3866799A (en) Cytoplasmic antiproteinase-3 coding sequence in gene therapy
AU2002319200A1 (en) Vector and the use thereof in gene therapy methods
AU5309500A (en) Novel human genes and proteins encoded thereby
HUP9900045A3 (en) Improved leukaemic blood-based product and their use in therapy

Legal Events

Date Code Title Description
MK6 Application lapsed section 142(2)(f)/reg. 8.3(3) - pct applic. not entering national phase