AU5166873A - Tetrahydroimidazo or hexahydropyrimido-2,1-b-quinasolin-2-ones - Google Patents
Tetrahydroimidazo or hexahydropyrimido-2,1-b-quinasolin-2-onesInfo
- Publication number
- AU5166873A AU5166873A AU51668/73A AU5166873A AU5166873A AU 5166873 A AU5166873 A AU 5166873A AU 51668/73 A AU51668/73 A AU 51668/73A AU 5166873 A AU5166873 A AU 5166873A AU 5166873 A AU5166873 A AU 5166873A
- Authority
- AU
- Australia
- Prior art keywords
- quinasolin
- hexahydropyrimido
- tetrahydroimidazo
- ones
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D487/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00
- C07D487/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00 in which the condensed system contains two hetero rings
- C07D487/04—Ortho-condensed systems
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
- A61K31/505—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P7/00—Drugs for disorders of the blood or the extracellular fluid
- A61P7/02—Antithrombotic agents; Anticoagulants; Platelet aggregation inhibitors
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/12—Antihypertensives
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D317/00—Heterocyclic compounds containing five-membered rings having two oxygen atoms as the only ring hetero atoms
- C07D317/08—Heterocyclic compounds containing five-membered rings having two oxygen atoms as the only ring hetero atoms having the hetero atoms in positions 1 and 3
- C07D317/44—Heterocyclic compounds containing five-membered rings having two oxygen atoms as the only ring hetero atoms having the hetero atoms in positions 1 and 3 ortho- or peri-condensed with carbocyclic rings or ring systems
- C07D317/46—Heterocyclic compounds containing five-membered rings having two oxygen atoms as the only ring hetero atoms having the hetero atoms in positions 1 and 3 ortho- or peri-condensed with carbocyclic rings or ring systems condensed with one six-membered ring
- C07D317/48—Methylenedioxybenzenes or hydrogenated methylenedioxybenzenes, unsubstituted on the hetero ring
- C07D317/62—Methylenedioxybenzenes or hydrogenated methylenedioxybenzenes, unsubstituted on the hetero ring with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to atoms of the carbocyclic ring
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D317/00—Heterocyclic compounds containing five-membered rings having two oxygen atoms as the only ring hetero atoms
- C07D317/08—Heterocyclic compounds containing five-membered rings having two oxygen atoms as the only ring hetero atoms having the hetero atoms in positions 1 and 3
- C07D317/44—Heterocyclic compounds containing five-membered rings having two oxygen atoms as the only ring hetero atoms having the hetero atoms in positions 1 and 3 ortho- or peri-condensed with carbocyclic rings or ring systems
- C07D317/46—Heterocyclic compounds containing five-membered rings having two oxygen atoms as the only ring hetero atoms having the hetero atoms in positions 1 and 3 ortho- or peri-condensed with carbocyclic rings or ring systems condensed with one six-membered ring
- C07D317/48—Methylenedioxybenzenes or hydrogenated methylenedioxybenzenes, unsubstituted on the hetero ring
- C07D317/62—Methylenedioxybenzenes or hydrogenated methylenedioxybenzenes, unsubstituted on the hetero ring with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to atoms of the carbocyclic ring
- C07D317/66—Nitrogen atoms not forming part of a nitro radical
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- General Health & Medical Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Life Sciences & Earth Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
- Medicinal Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- General Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Engineering & Computer Science (AREA)
- Hematology (AREA)
- Diabetes (AREA)
- Epidemiology (AREA)
- Cardiology (AREA)
- Heart & Thoracic Surgery (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Nitrogen Condensed Heterocyclic Rings (AREA)
Applications Claiming Priority (4)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US22372372A | 1972-02-04 | 1972-02-04 | |
USUS223,723 | 1972-02-04 | ||
US29145072A | 1972-09-22 | 1972-09-22 | |
USUS291,450 | 1972-09-22 |
Publications (2)
Publication Number | Publication Date |
---|---|
AU5166873A true AU5166873A (en) | 1974-08-01 |
AU475978B2 AU475978B2 (en) | 1976-09-09 |
Family
ID=26918072
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
AU51668/73A Expired AU475978B2 (en) | 1972-02-04 | 1973-02-01 | Tetrahydroimidazo or hexahydropyrimido-2,1-b-quinasolin-2-ones |
Country Status (9)
Country | Link |
---|---|
JP (1) | JPS5623994B2 (en) |
AU (1) | AU475978B2 (en) |
BE (1) | BE794964A (en) |
CA (1) | CA1009652A (en) |
DE (1) | DE2305575A1 (en) |
FR (1) | FR2173988B1 (en) |
GB (1) | GB1418822A (en) |
HK (1) | HK15581A (en) |
YU (2) | YU210773A (en) |
Families Citing this family (25)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
USRE31617E (en) * | 1972-02-04 | 1984-06-26 | Bristol-Myers Company | Optionally substituted 1,2,3,5-tetrahydroimidezo(2,1-b)-quinazolin-2-ones and 6(H)-1,2,3,4-tetrahydropyimido(2,1-b)quinazolin-2-ones |
NL7807507A (en) * | 1977-07-25 | 1979-01-29 | Hoffmann La Roche | TRICYCLICAL CONNECTIONS. |
US4146718A (en) * | 1978-04-10 | 1979-03-27 | Bristol-Myers Company | Alkyl 5,6-dichloro-3,4-dihydro-2(1h)-iminoquinazoline-3-acetate hydrohalides |
CA1131631A (en) * | 1979-06-20 | 1982-09-14 | Madhukar S. Chodnekar | Quinazoline derivatives and pharmaceutical preparations |
ZW16481A1 (en) * | 1980-08-15 | 1982-03-10 | Hoffmann La Roche | Novel imidazoquinazoline derivatives |
JPS6028979A (en) * | 1983-07-14 | 1985-02-14 | Dai Ichi Seiyaku Co Ltd | Imidazoquinazoline compound |
HUT66324A (en) * | 1991-07-29 | 1994-11-28 | Warner Lambert Co | Quinazoline derivatives as acetylcholinesterase inhibitors and pharmaceutical compositions containing them |
AU705229B2 (en) | 1994-08-09 | 1999-05-20 | Eisai R&D Management Co., Ltd. | Fused pyridazine compound |
US7772188B2 (en) | 2003-01-28 | 2010-08-10 | Ironwood Pharmaceuticals, Inc. | Methods and compositions for the treatment of gastrointestinal disorders |
US8304420B2 (en) | 2006-11-28 | 2012-11-06 | Shire Llc | Substituted quinazolines for reducing platelet count |
WO2008151257A2 (en) | 2007-06-04 | 2008-12-11 | Synergy Pharmaceuticals Inc. | Agonists of guanylate cyclase useful for the treatment of gastrointestinal disorders, inflammation, cancer and other disorders |
US8969514B2 (en) | 2007-06-04 | 2015-03-03 | Synergy Pharmaceuticals, Inc. | Agonists of guanylate cyclase useful for the treatment of hypercholesterolemia, atherosclerosis, coronary heart disease, gallstone, obesity and other cardiovascular diseases |
GB0808947D0 (en) * | 2008-05-16 | 2008-06-25 | Shire Llc | Substituted quinazolines |
GB0808968D0 (en) * | 2008-05-16 | 2008-06-25 | Shire Llc | Substitute quinazolines |
AU2009256157B2 (en) | 2008-06-04 | 2014-12-18 | Bausch Health Ireland Limited | Agonists of guanylate cyclase useful for the treatment of gastrointestinal disorders, inflammation, cancer and other disorders |
EP2321341B1 (en) | 2008-07-16 | 2017-02-22 | Synergy Pharmaceuticals Inc. | Agonists of guanylate cyclase useful for the treatment of gastrointestinal, inflammation, cancer and other disorders |
US9616097B2 (en) | 2010-09-15 | 2017-04-11 | Synergy Pharmaceuticals, Inc. | Formulations of guanylate cyclase C agonists and methods of use |
EA201391254A1 (en) | 2011-03-01 | 2014-02-28 | Синерджи Фармасьютикалз Инк. | METHOD FOR OBTAINING GUANYLATZCLAZE AGONISTS C |
CA2902348C (en) | 2013-02-25 | 2021-11-30 | Synergy Pharmaceuticals Inc. | Agonists of guanylate cyclase and their uses |
WO2014151206A1 (en) | 2013-03-15 | 2014-09-25 | Synergy Pharmaceuticals Inc. | Agonists of guanylate cyclase and their uses |
AU2014235209B2 (en) | 2013-03-15 | 2018-06-14 | Bausch Health Ireland Limited | Guanylate cyclase receptor agonists combined with other drugs |
WO2014197720A2 (en) | 2013-06-05 | 2014-12-11 | Synergy Pharmaceuticals, Inc. | Ultra-pure agonists of guanylate cyclase c, method of making and using same |
US20160184387A1 (en) | 2013-08-09 | 2016-06-30 | Dominique Charmot | Compounds and methods for inhibiting phosphate transport |
CN114340631A (en) | 2019-05-21 | 2022-04-12 | 阿德利克斯股份有限公司 | Combination for reducing serum phosphate in a patient |
WO2022199627A1 (en) * | 2021-03-23 | 2022-09-29 | National Institute Of Biological Sciences, Beijing | Polycyclic compounds and uses thereof |
Family Cites Families (1)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
BE760013A (en) * | 1969-12-18 | 1971-06-08 | Smith Kline French Lab | IMIDAZO AND PYRIMIDO - (2,1-B) QUINAZOLINES, THEIR PREPARATION PROCESSES AND PHARMACEUTICAL COMPOSITIONS CONTAINING |
-
0
- BE BE794964D patent/BE794964A/en not_active IP Right Cessation
-
1973
- 1973-02-01 AU AU51668/73A patent/AU475978B2/en not_active Expired
- 1973-02-02 JP JP1303873A patent/JPS5623994B2/ja not_active Expired
- 1973-02-02 FR FR7303843A patent/FR2173988B1/fr not_active Expired
- 1973-02-02 GB GB539073A patent/GB1418822A/en not_active Expired
- 1973-02-02 CA CA162,747A patent/CA1009652A/en not_active Expired
- 1973-02-05 DE DE19732305575 patent/DE2305575A1/en active Granted
- 1973-08-03 YU YU02107/73A patent/YU210773A/en unknown
-
1981
- 1981-04-23 HK HK155/81A patent/HK15581A/en unknown
- 1981-06-15 YU YU01510/81A patent/YU151081A/en unknown
Also Published As
Publication number | Publication date |
---|---|
JPS5623994B2 (en) | 1981-06-03 |
YU151081A (en) | 1983-12-31 |
DE2305575A1 (en) | 1973-08-09 |
AU475978B2 (en) | 1976-09-09 |
BE794964A (en) | 1973-08-02 |
YU210773A (en) | 1983-02-28 |
GB1418822A (en) | 1975-12-24 |
FR2173988A1 (en) | 1973-10-12 |
DE2305575C2 (en) | 1989-01-12 |
JPS4886894A (en) | 1973-11-15 |
HK15581A (en) | 1981-05-01 |
CA1009652A (en) | 1977-05-03 |
FR2173988B1 (en) | 1976-10-22 |
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