AU514499B2 - Hentriakontapeptides - Google Patents

Hentriakontapeptides

Info

Publication number
AU514499B2
AU514499B2 AU23298/77A AU2329877A AU514499B2 AU 514499 B2 AU514499 B2 AU 514499B2 AU 23298/77 A AU23298/77 A AU 23298/77A AU 2329877 A AU2329877 A AU 2329877A AU 514499 B2 AU514499 B2 AU 514499B2
Authority
AU
Australia
Prior art keywords
hentriakontapeptides
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired
Application number
AU23298/77A
Other languages
English (en)
Other versions
AU2329877A (en
Inventor
CH Li
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
University of California
Original Assignee
F Hoffmann La Roche AG
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by F Hoffmann La Roche AG filed Critical F Hoffmann La Roche AG
Publication of AU2329877A publication Critical patent/AU2329877A/en
Application granted granted Critical
Publication of AU514499B2 publication Critical patent/AU514499B2/en
Expired legal-status Critical Current

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K14/00Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/665Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans derived from pro-opiomelanocortin, pro-enkephalin or pro-dynorphin
    • C07K14/675Beta-endorphins
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • A61P25/04Centrally acting analgesics, e.g. opioids
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P5/00Drugs for disorders of the endocrine system
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00Medicinal preparations containing peptides
    • YGENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y02TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
    • Y02PCLIMATE CHANGE MITIGATION TECHNOLOGIES IN THE PRODUCTION OR PROCESSING OF GOODS
    • Y02P20/00Technologies relating to chemical industry
    • Y02P20/50Improvements relating to the production of bulk chemicals
    • Y02P20/55Design of synthesis routes, e.g. reducing the use of auxiliary or protecting groups
    • YGENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10STECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10S930/00Peptide or protein sequence
    • Y10S930/01Peptide or protein sequence
    • Y10S930/28Bound to a nonpeptide drug, nonpeptide label, nonpeptide carrier, or a nonpeptide resin

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Organic Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • General Chemical & Material Sciences (AREA)
  • Biophysics (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Molecular Biology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Animal Behavior & Ethology (AREA)
  • Engineering & Computer Science (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Genetics & Genomics (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Biochemistry (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Toxicology (AREA)
  • Zoology (AREA)
  • Neurosurgery (AREA)
  • Neurology (AREA)
  • Biomedical Technology (AREA)
  • Pain & Pain Management (AREA)
  • Diabetes (AREA)
  • Endocrinology (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Peptides Or Proteins (AREA)
AU23298/77A 1976-03-17 1977-03-06 Hentriakontapeptides Expired AU514499B2 (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
USUS667747 1976-03-17
US05/667,747 US4038222A (en) 1976-03-17 1976-03-17 Untriakontapeptide with opiate activity

Publications (2)

Publication Number Publication Date
AU2329877A AU2329877A (en) 1978-09-21
AU514499B2 true AU514499B2 (en) 1981-02-12

Family

ID=24679466

Family Applications (1)

Application Number Title Priority Date Filing Date
AU23298/77A Expired AU514499B2 (en) 1976-03-17 1977-03-06 Hentriakontapeptides

Country Status (26)

Country Link
US (2) US4038222A (US06373033-20020416-M00071.png)
JP (1) JPS52113958A (US06373033-20020416-M00071.png)
AR (2) AR222778A1 (US06373033-20020416-M00071.png)
AT (1) AT355238B (US06373033-20020416-M00071.png)
AU (1) AU514499B2 (US06373033-20020416-M00071.png)
BE (1) BE852510A (US06373033-20020416-M00071.png)
CA (1) CA1092602A (US06373033-20020416-M00071.png)
CH (1) CH625785A5 (US06373033-20020416-M00071.png)
DE (1) DE2711487C2 (US06373033-20020416-M00071.png)
DK (1) DK149203C (US06373033-20020416-M00071.png)
ES (2) ES456901A1 (US06373033-20020416-M00071.png)
FI (1) FI63391C (US06373033-20020416-M00071.png)
FR (1) FR2348912A1 (US06373033-20020416-M00071.png)
GB (1) GB1563654A (US06373033-20020416-M00071.png)
GR (1) GR63092B (US06373033-20020416-M00071.png)
IE (1) IE44226B1 (US06373033-20020416-M00071.png)
IL (1) IL51660A (US06373033-20020416-M00071.png)
LU (1) LU76963A1 (US06373033-20020416-M00071.png)
MC (1) MC1137A1 (US06373033-20020416-M00071.png)
NL (1) NL7702849A (US06373033-20020416-M00071.png)
NO (1) NO147105C (US06373033-20020416-M00071.png)
NZ (1) NZ183605A (US06373033-20020416-M00071.png)
PH (1) PH13864A (US06373033-20020416-M00071.png)
PT (1) PT66311B (US06373033-20020416-M00071.png)
SE (1) SE436354B (US06373033-20020416-M00071.png)
ZA (1) ZA771593B (US06373033-20020416-M00071.png)

Families Citing this family (48)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4320117A (en) * 1976-06-21 1982-03-16 Imperial Chemical Industries Limited Polypeptide
US4123523A (en) * 1976-06-21 1978-10-31 Imperial Chemical Industries Limited Analgesic and sedative polypeptides
US4371463A (en) * 1977-02-17 1983-02-01 The United States Of America As Represented By The Department Of Health And Human Services Enzyme-resistant opiate pentapeptides
US4081434A (en) * 1977-03-11 1978-03-28 Hoffmann-La Roche Inc. Novel analogs of β-endorphin
US4317770A (en) * 1977-03-11 1982-03-02 Hoffmann-La Roche Inc. D-amino acid analogs of beta-endorphin
US4098781A (en) * 1977-03-11 1978-07-04 American Home Products Corporation Polypeptides with morphine-like activity
US4127522A (en) * 1977-06-16 1978-11-28 Coy David Howard Novel triacontapeptides, intermediates therefor and pharmaceutical compositions and methods employing said triacontapeptides
US4127528A (en) * 1977-06-16 1978-11-28 Coy David Howard Novel derivatives of alpha-endorphin, intermediates therefor and compositions and methods employing said derivatives
US4127518A (en) * 1977-06-16 1978-11-28 Coy David Howard Novel derivatives of gamma-endorphins, intermediates therefor, and compositions and methods employing said derivatives
US4127532A (en) * 1977-06-16 1978-11-28 Coy David Howard Novel heptapeptides, intermediates therefor, and compositions and methods employing said heptapeptides
US4127536A (en) * 1977-06-16 1978-11-28 Coy David Howard Novel tricosapeptides, intermediates therefor and pharmaceutical compositions and methods employing said tricosapeptides
US4127526A (en) * 1977-06-16 1978-11-28 Coy David Howard Novel tetradecapeptides, intermediates therefor, and compositions and methods employing said tetradecapeptides
US4127523A (en) * 1977-06-16 1978-11-28 Coy David Howard Novel undecapeptides, intermediates therefor, and compositions and methods employing said undecapeptides
US4127541A (en) * 1977-06-16 1978-11-28 Coy David Howard Novel decapeptides, intermediates therefor, and compositions and methods employing said decapeptides
US4127537A (en) * 1977-06-16 1978-11-28 Coy David Howard Novel tetracosapeptides, intermediates therefor and pharmaceutical compositions and methods employing said tetracosapeptides
US4127520A (en) * 1977-06-16 1978-11-28 Coy David Howard Novel nonadecapeptides, intermediates therefor, and compositions and methods employing said nonadecapeptides
US4127517A (en) * 1977-06-16 1978-11-28 Coy David Howard Novel docosapeptides, intermediates therefore and pharmaceutical compositions and methods employing said docosapeptides
ZA783287B (en) * 1977-06-16 1980-01-30 D Coy Novel polypeptides
US4127533A (en) * 1977-06-16 1978-11-28 Coy David Howard Novel octapeptides, intermediates therefor, and compositions and methods employing said octapeptides
US4127534A (en) * 1977-06-16 1978-11-28 Coy David Howard Novel tripeptides, intermediates therefor and pharmaceutical compositions and methods employing said tripeptides
US4127538A (en) * 1977-06-16 1978-11-28 Coy David Howard Novel pentacosapeptides, intermediates therefor and pharmaceutical compositions and methods employing said pentacosapeptides
US4127540A (en) * 1977-06-16 1978-11-28 Coy David Howard Novel derivatives of δ-endorphins, intermediates therefor, and compositions and methods employing said derivatives
US4127525A (en) * 1977-06-16 1978-11-28 Coy David Howard Novel tridecapeptides, intermediates therefor, and compositions and methods employing said tridecapeptides
US4127521A (en) * 1977-06-16 1978-11-28 Coy David Howard Novel octacosapeptides, intermediates therefor and pharmaceutical compositions and methods employing said octacosapeptides
US4127530A (en) * 1977-06-16 1978-11-28 Coy David Howard Novel heneicosapeptides, intermediates therefor and pharmaceutical compositions and methods employing said heneicosapeptides
US4127519A (en) * 1977-06-16 1978-11-28 Coy David Howard Octadecapeptides, intermediates therefor, and compositions and methods employing said octadecapeptides
US4127527A (en) * 1977-06-16 1978-11-28 Coy David Howard Novel pentadecapeptides, intermediates therefor, and compositions and methods employing said pentadecapeptides
US4312857A (en) * 1977-06-16 1982-01-26 The United States Of America As Represented By The Veterans Administration Novel derivatives of beta-endorphin, intermediates therefor and compositions and methods employing said derivatives
US4127524A (en) * 1977-06-16 1978-11-28 Coy David Howard Novel dodecapeptides, intermediates therefor, and compositions and methods employing said dodecapeptides
US4139504A (en) * 1977-06-16 1979-02-13 Coy David Howard Novel nonapeptides, intermediates therefor, and compositions and methods employing said nonapeptides
US4127535A (en) * 1977-06-16 1978-11-28 Coy David Howard Novel dipeptides, intermediates therefor, and compositions and methods employing said dipeptides
US4127531A (en) * 1977-06-16 1978-11-28 Coy David Howard Novel hexapeptides, intermediates therefor, and compositions and methods employing said hexapeptides
US4127529A (en) * 1977-06-16 1978-11-28 Coy David Howard Novel eicosapeptides, intermediates therefor and pharmaceutical compositions and methods employing said eicosapeptides
US4127539A (en) * 1977-06-16 1978-11-28 Coy David Howard Novel hexacosapeptides, intermediates therefore and pharmaceutical compositions and methods employing said hexacosapeptides
US4105652A (en) * 1977-08-05 1978-08-08 Hoffmann-La Roche Inc. Synthesis of human β-endorphin
US4232008A (en) * 1978-11-17 1980-11-04 Ortho Pharmaceutical Corporation Tetrapeptides and methods
US4116950A (en) * 1978-01-16 1978-09-26 Hoffmann-La Roche Inc. Analogs of human β-endorphin
US4330465A (en) * 1978-03-02 1982-05-18 Hoffmann-La Roche Inc. Novel β-endorphin analogs
US4219468A (en) * 1978-11-13 1980-08-26 Hoffmann-La Roche Inc. Tritiated β-endorphin
US4396606A (en) 1979-11-05 1983-08-02 Addiction Research Foundation Novel polypeptide analgesics
US4250087A (en) * 1979-12-10 1981-02-10 Hoffmann-La Roche Inc. Carboxyl terminus analogs of β-endorphin
JPS56108750A (en) * 1980-02-01 1981-08-28 Takeda Chem Ind Ltd Polypeptide and its preparation
US4438104A (en) 1980-01-03 1984-03-20 Endorphin, Inc. Endorphins having placental or pancreatic origin
US4316895A (en) * 1980-01-03 1982-02-23 Kimball Charles D Endorphins having placental or pancreatic origin
US4350764A (en) * 1980-03-10 1982-09-21 The Regents Of The University Of California Microbiological synthesis of beta endorphin
US4313937A (en) * 1980-08-12 1982-02-02 Tsutomu Oyama Method for producing long-lasting analgesic effects of β-endorphin
GB2111505B (en) * 1981-06-16 1984-09-26 Charles D Kimball Endorphins having placental or pancreatic origin
FR2857873B1 (fr) * 2003-07-21 2006-02-24 Courtage Et De Diffusion Codif Procede et produit cosmetique destines a limiter la croissance des tissus adipeux

Also Published As

Publication number Publication date
ES467453A1 (es) 1978-10-16
LU76963A1 (US06373033-20020416-M00071.png) 1978-06-01
SE436354B (sv) 1984-12-03
USRE29842E (en) 1978-11-21
IE44226L (en) 1977-09-17
ATA178877A (de) 1979-07-15
DE2711487C2 (de) 1986-12-11
NO147105B (no) 1982-10-25
ZA771593B (en) 1978-01-25
FI63391B (fi) 1983-02-28
IE44226B1 (en) 1981-09-09
PT66311A (en) 1977-04-01
GR63092B (en) 1979-08-13
SE7703004L (sv) 1977-09-18
FI63391C (fi) 1983-06-10
NL7702849A (nl) 1977-09-20
PT66311B (en) 1979-01-17
DK149203C (da) 1986-08-04
BE852510A (fr) 1977-09-16
CH625785A5 (US06373033-20020416-M00071.png) 1981-10-15
NZ183605A (en) 1980-02-21
AU2329877A (en) 1978-09-21
MC1137A1 (fr) 1977-11-18
IL51660A (en) 1980-02-29
US4038222A (en) 1977-07-26
ES456901A1 (es) 1978-07-16
AR222007A1 (es) 1981-04-15
JPS62159B2 (US06373033-20020416-M00071.png) 1987-01-06
AT355238B (de) 1980-02-25
NO147105C (no) 1983-02-02
PH13864A (en) 1980-10-22
NO770941L (no) 1977-09-20
IL51660A0 (en) 1977-05-31
AR222778A1 (es) 1981-06-30
JPS52113958A (en) 1977-09-24
FR2348912B1 (US06373033-20020416-M00071.png) 1981-02-13
DK149203B (da) 1986-03-10
FI770835A (US06373033-20020416-M00071.png) 1977-09-18
CA1092602A (en) 1980-12-30
DK116177A (da) 1977-09-18
GB1563654A (en) 1980-03-26
DE2711487A1 (de) 1977-09-22
FR2348912A1 (fr) 1977-11-18

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