AU512700B2 - 2-amino-12-benzyl-1,2,3,4,6,7,12,126-octahydroindolo-(2,3-a) quinolizine - Google Patents

2-amino-12-benzyl-1,2,3,4,6,7,12,126-octahydroindolo-(2,3-a) quinolizine

Info

Publication number
AU512700B2
AU512700B2 AU47910/79A AU4791079A AU512700B2 AU 512700 B2 AU512700 B2 AU 512700B2 AU 47910/79 A AU47910/79 A AU 47910/79A AU 4791079 A AU4791079 A AU 4791079A AU 512700 B2 AU512700 B2 AU 512700B2
Authority
AU
Australia
Prior art keywords
octahydroindolo
quinolizine
benzyl
amino
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired
Application number
AU47910/79A
Other versions
AU4791079A (en
Inventor
Herbert John Havera
Richard Don Johnson
Horacio Vidrio
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Bayer Corp
Original Assignee
Miles Laboratories Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Miles Laboratories Inc filed Critical Miles Laboratories Inc
Publication of AU4791079A publication Critical patent/AU4791079A/en
Application granted granted Critical
Publication of AU512700B2 publication Critical patent/AU512700B2/en
Anticipated expiration legal-status Critical
Expired legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D471/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
    • C07D471/12—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains three hetero rings
    • C07D471/14—Ortho-condensed systems
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/06—Antiarrhythmics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/08—Vasodilators for multiple indications
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/12—Antihypertensives

Landscapes

  • Health & Medical Sciences (AREA)
  • Organic Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • General Chemical & Material Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Cardiology (AREA)
  • Medicinal Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Veterinary Medicine (AREA)
  • Urology & Nephrology (AREA)
  • Vascular Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
AU47910/79A 1978-07-14 1979-06-08 2-amino-12-benzyl-1,2,3,4,6,7,12,126-octahydroindolo-(2,3-a) quinolizine Expired AU512700B2 (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US05/924,622 US4181657A (en) 1978-07-14 1978-07-14 2-Aminooctahydroindolo[2,3-a]quinolizines useful in treating cardiovascular disorders
US924622 1997-09-05

Publications (2)

Publication Number Publication Date
AU4791079A AU4791079A (en) 1980-01-17
AU512700B2 true AU512700B2 (en) 1980-10-23

Family

ID=25450450

Family Applications (1)

Application Number Title Priority Date Filing Date
AU47910/79A Expired AU512700B2 (en) 1978-07-14 1979-06-08 2-amino-12-benzyl-1,2,3,4,6,7,12,126-octahydroindolo-(2,3-a) quinolizine

Country Status (8)

Country Link
US (1) US4181657A (en)
JP (1) JPS5515468A (en)
AU (1) AU512700B2 (en)
CA (1) CA1108147A (en)
DE (1) DE2924880A1 (en)
FR (1) FR2430947A1 (en)
GB (1) GB2027017B (en)
IL (1) IL57546A (en)

Families Citing this family (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4358452A (en) * 1980-05-09 1982-11-09 John Wyeth & Brother Limited N-[1,2,3,4,6,7,12,12 α-octahydro-2H-indolo(2,3α)-quinolizinyl-2β-yl]alkane and benzyl sulfonamides and anti-hypertensive use thereof
JPS5843085A (en) * 1981-09-07 1983-03-12 オムロン株式会社 Coin processor
ATE25383T1 (en) * 1981-11-18 1987-02-15 Thal Claude INDOLOQUINOLIZIN DERIVATIVES, PROCESS FOR THEIR PRODUCTION AND THEIR THERAPEUTIC APPLICATION.
JPS5897431U (en) * 1981-12-22 1983-07-02 コロナ工業株式会社 Combustion furnace solid fuel supply device
JPS58121253A (en) * 1982-01-13 1983-07-19 Konishiroku Photo Ind Co Ltd Preparation of alpha-aminophenoxy fatty acid and ester thereof
US4690928A (en) * 1984-02-02 1987-09-01 Merck & Co., Inc. Substituted hexahydro arylquinolizines as α2 blockers
IL74147A (en) * 1984-02-02 1988-08-31 Merck & Co Inc 2-acylamino-hexahydro-arylquinolizines and salts thereof and pharmaceutical compositions containing them

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DK102805C (en) * 1962-01-15 1965-10-11 Koninklijke Pharma Fab Nv Process for the preparation of indoloquinolizine derivatives or salts thereof.
GB1435573A (en) * 1973-05-25 1976-05-12 Wyeth John & Brother Ltd Indoloquinolizines

Also Published As

Publication number Publication date
FR2430947B1 (en) 1981-10-30
IL57546A (en) 1982-08-31
DE2924880A1 (en) 1980-01-24
FR2430947A1 (en) 1980-02-08
GB2027017A (en) 1980-02-13
JPS5515468A (en) 1980-02-02
JPS5640157B2 (en) 1981-09-18
AU4791079A (en) 1980-01-17
IL57546A0 (en) 1979-10-31
GB2027017B (en) 1982-11-17
CA1108147A (en) 1981-09-01
US4181657A (en) 1980-01-01

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