AU5082993A - Cationic-2-heteroarylphenyl-carbapenem antibacterial agents - Google Patents
Cationic-2-heteroarylphenyl-carbapenem antibacterial agentsInfo
- Publication number
- AU5082993A AU5082993A AU50829/93A AU5082993A AU5082993A AU 5082993 A AU5082993 A AU 5082993A AU 50829/93 A AU50829/93 A AU 50829/93A AU 5082993 A AU5082993 A AU 5082993A AU 5082993 A AU5082993 A AU 5082993A
- Authority
- AU
- Australia
- Prior art keywords
- heteroarylphenyl
- cationic
- antibacterial agents
- carbapenem antibacterial
- carbapenem
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Abandoned
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D231/00—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings
- C07D231/02—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings not condensed with other rings
- C07D231/10—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members
- C07D231/12—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached to ring carbon atoms
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/04—Antibacterial agents
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D233/00—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings
- C07D233/54—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having two double bonds between ring members or between ring members and non-ring members
- C07D233/56—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having two double bonds between ring members or between ring members and non-ring members with only hydrogen atoms or radicals containing only hydrogen and carbon atoms, attached to ring carbon atoms
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D249/00—Heterocyclic compounds containing five-membered rings having three nitrogen atoms as the only ring hetero atoms
- C07D249/02—Heterocyclic compounds containing five-membered rings having three nitrogen atoms as the only ring hetero atoms not condensed with other rings
- C07D249/08—1,2,4-Triazoles; Hydrogenated 1,2,4-triazoles
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D477/00—Heterocyclic compounds containing 1-azabicyclo [3.2.0] heptane ring systems, i.e. compounds containing a ring system of the formula:, e.g. carbapenicillins, thienamycins; Such ring systems being further condensed, e.g. 2,3-condensed with an oxygen-, nitrogen- or sulphur-containing hetero ring
- C07D477/10—Heterocyclic compounds containing 1-azabicyclo [3.2.0] heptane ring systems, i.e. compounds containing a ring system of the formula:, e.g. carbapenicillins, thienamycins; Such ring systems being further condensed, e.g. 2,3-condensed with an oxygen-, nitrogen- or sulphur-containing hetero ring with hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached in position 4, and with a carbon atom having three bonds to hetero atoms with at the most one bond to halogen, e.g. an ester or nitrile radical, directly attached in position 2
- C07D477/12—Heterocyclic compounds containing 1-azabicyclo [3.2.0] heptane ring systems, i.e. compounds containing a ring system of the formula:, e.g. carbapenicillins, thienamycins; Such ring systems being further condensed, e.g. 2,3-condensed with an oxygen-, nitrogen- or sulphur-containing hetero ring with hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached in position 4, and with a carbon atom having three bonds to hetero atoms with at the most one bond to halogen, e.g. an ester or nitrile radical, directly attached in position 2 with hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, attached in position 6
- C07D477/14—Heterocyclic compounds containing 1-azabicyclo [3.2.0] heptane ring systems, i.e. compounds containing a ring system of the formula:, e.g. carbapenicillins, thienamycins; Such ring systems being further condensed, e.g. 2,3-condensed with an oxygen-, nitrogen- or sulphur-containing hetero ring with hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached in position 4, and with a carbon atom having three bonds to hetero atoms with at the most one bond to halogen, e.g. an ester or nitrile radical, directly attached in position 2 with hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, attached in position 6 with hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, attached in position 3
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Communicable Diseases (AREA)
- Oncology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Pharmacology & Pharmacy (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Nitrogen Condensed Heterocyclic Rings (AREA)
Applications Claiming Priority (5)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US937618 | 1992-08-28 | ||
US937632 | 1992-08-28 | ||
US07/937,618 US5342933A (en) | 1992-08-28 | 1992-08-28 | Cationic-2-heteroarylphenyl-carbapenem antibacterial agents |
US07/937,632 US5292879A (en) | 1992-08-28 | 1992-08-28 | Intermediates for preparing cationic-2-heteroaryl-phenyl-carbapenem antibacterial agents |
PCT/US1993/007830 WO1994005669A1 (en) | 1992-08-28 | 1993-08-19 | Cationic-2-heteroarylphenyl-carbapenem antibacterial agents |
Publications (1)
Publication Number | Publication Date |
---|---|
AU5082993A true AU5082993A (en) | 1994-03-29 |
Family
ID=27130104
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
AU50829/93A Abandoned AU5082993A (en) | 1992-08-28 | 1993-08-19 | Cationic-2-heteroarylphenyl-carbapenem antibacterial agents |
Country Status (5)
Country | Link |
---|---|
EP (1) | EP0656900A4 (en) |
JP (1) | JPH08500835A (en) |
AU (1) | AU5082993A (en) |
CA (1) | CA2142708A1 (en) |
WO (1) | WO1994005669A1 (en) |
Families Citing this family (4)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US20020137940A1 (en) | 1997-12-16 | 2002-09-26 | Smithkline Beecham P.L.C. | 5-[4-[2-(N-methyl-N-(2-pyridyl)amino)ethoxy]benzyl]thiazolidine-2, 4-dione, maleic acid salt, hydrate as pharmaceutical |
US6664278B2 (en) | 1997-12-16 | 2003-12-16 | Smithkline Beecham P.L.C. | Hydrate of 5-[4-[2-(N-methyl-N-(2-pyridil)amino)ethoxy]benzyl]thiazolidine-2,4-dione maleic acid salt |
GB9726568D0 (en) | 1997-12-16 | 1998-02-11 | Smithkline Beecham Plc | Novel pharmaceutical |
WO1999055668A1 (en) | 1998-04-27 | 1999-11-04 | Kumiai Chemical Industry Co., Ltd. | 3-arylphenyl sulfide derivatives and insecticides and miticides |
Family Cites Families (3)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US4543257A (en) * | 1977-10-19 | 1985-09-24 | Merck & Co., Inc. | 1-Carba-2-penem-3-carboxylic acid |
US4978659A (en) * | 1987-02-02 | 1990-12-18 | Merck & Co., Inc. | 2-(Heteroaryliumalkyl)phenyl carbapenem antibacterial agents |
US5143914A (en) * | 1991-06-25 | 1992-09-01 | Merck & Co., Inc. | 2-heteroarylphenyl-carbapenem antibacterial agents |
-
1993
- 1993-08-19 AU AU50829/93A patent/AU5082993A/en not_active Abandoned
- 1993-08-19 CA CA002142708A patent/CA2142708A1/en not_active Abandoned
- 1993-08-19 EP EP93920228A patent/EP0656900A4/en not_active Withdrawn
- 1993-08-19 WO PCT/US1993/007830 patent/WO1994005669A1/en not_active Application Discontinuation
- 1993-08-19 JP JP6507242A patent/JPH08500835A/en active Pending
Also Published As
Publication number | Publication date |
---|---|
EP0656900A1 (en) | 1995-06-14 |
JPH08500835A (en) | 1996-01-30 |
CA2142708A1 (en) | 1994-03-17 |
WO1994005669A1 (en) | 1994-03-17 |
EP0656900A4 (en) | 1995-09-06 |
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