AU5015193A - Prevention or treatment of sepsis with dantrolene or azumolene - Google Patents

Prevention or treatment of sepsis with dantrolene or azumolene

Info

Publication number
AU5015193A
AU5015193A AU50151/93A AU5015193A AU5015193A AU 5015193 A AU5015193 A AU 5015193A AU 50151/93 A AU50151/93 A AU 50151/93A AU 5015193 A AU5015193 A AU 5015193A AU 5015193 A AU5015193 A AU 5015193A
Authority
AU
Australia
Prior art keywords
azumolene
dantrolene
sepsis
prevention
treatment
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Abandoned
Application number
AU50151/93A
Inventor
Joseph John Henry Ackerman
Richard Samuel Hotchkiss
Irene Elsie Karl
Sheng-Kwei Song
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Washington University in St Louis WUSTL
Original Assignee
University of Washington
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by University of Washington filed Critical University of Washington
Publication of AU5015193A publication Critical patent/AU5015193A/en
Abandoned legal-status Critical Current

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/41—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
    • A61K31/415—1,2-Diazoles
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/41—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
    • A61K31/42—Oxazoles

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
AU50151/93A 1992-09-09 1993-08-17 Prevention or treatment of sepsis with dantrolene or azumolene Abandoned AU5015193A (en)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US94266292A 1992-09-09 1992-09-09
US942662 1992-09-09
PCT/US1993/007698 WO1994005287A1 (en) 1992-09-09 1993-08-17 Prevention or treatment of sepsis with dantrolene or azumolene

Publications (1)

Publication Number Publication Date
AU5015193A true AU5015193A (en) 1994-03-29

Family

ID=25478428

Family Applications (1)

Application Number Title Priority Date Filing Date
AU50151/93A Abandoned AU5015193A (en) 1992-09-09 1993-08-17 Prevention or treatment of sepsis with dantrolene or azumolene

Country Status (3)

Country Link
CN (1) CN1090491A (en)
AU (1) AU5015193A (en)
WO (1) WO1994005287A1 (en)

Families Citing this family (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
KR100267258B1 (en) * 1997-12-27 2000-10-16 최동환 Protective antidotes of anthrax toxin-induced cytotoxicity
US7758890B2 (en) 2001-06-23 2010-07-20 Lyotropic Therapeutics, Inc. Treatment using dantrolene
AU2004262507B2 (en) * 2003-03-04 2010-02-18 Lyotropic Therapeutics, Inc. Treatment using dantrolene
EP2219605B1 (en) * 2007-10-09 2015-08-19 US Worldmeds LLC Co-solvent compositions and methods for improved delivery of dantrolene therapeutic agents
US20120040970A1 (en) * 2009-04-27 2012-02-16 Al-Ghananeem Abeer M Intranasal delivery system for dantrolene
US10441574B2 (en) 2014-11-13 2019-10-15 Washington University Treatment for wolfram syndrome and other endoplasmic reticulum stress disorders
WO2019095056A1 (en) * 2017-11-14 2019-05-23 University Health Network Dantrolene and analogs thereof for the chronic treatment and prevention of dyssynchronous cardiac dysfunction

Family Cites Families (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4861790A (en) * 1987-10-28 1989-08-29 Norwich Eaton Pharmaceuticals, Inc. Use of azumolene for the treatment of malignant hyperthermia

Also Published As

Publication number Publication date
CN1090491A (en) 1994-08-10
WO1994005287A1 (en) 1994-03-17

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