AU4973896A - Ink4c-p18 and ink4d-p19, inhibitors of cyclin-depedent kinases cdk4 and cdk6, and uses thereof - Google Patents
Ink4c-p18 and ink4d-p19, inhibitors of cyclin-depedent kinases cdk4 and cdk6, and uses thereofInfo
- Publication number
- AU4973896A AU4973896A AU49738/96A AU4973896A AU4973896A AU 4973896 A AU4973896 A AU 4973896A AU 49738/96 A AU49738/96 A AU 49738/96A AU 4973896 A AU4973896 A AU 4973896A AU 4973896 A AU4973896 A AU 4973896A
- Authority
- AU
- Australia
- Prior art keywords
- ink4d
- ink4c
- depedent
- cdk6
- cyclin
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Abandoned
Links
- 101100005789 Caenorhabditis elegans cdk-4 gene Proteins 0.000 title 1
- 108091000080 Phosphotransferase Proteins 0.000 title 1
- 239000003112 inhibitor Substances 0.000 title 1
- 102000020233 phosphotransferase Human genes 0.000 title 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- C07K14/46—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates
- C07K14/47—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates from mammals
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
-
- A—HUMAN NECESSITIES
- A01—AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
- A01K—ANIMAL HUSBANDRY; AVICULTURE; APICULTURE; PISCICULTURE; FISHING; REARING OR BREEDING ANIMALS, NOT OTHERWISE PROVIDED FOR; NEW BREEDS OF ANIMALS
- A01K2217/00—Genetically modified animals
- A01K2217/05—Animals comprising random inserted nucleic acids (transgenic)
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2319/00—Fusion polypeptide
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Organic Chemistry (AREA)
- General Health & Medical Sciences (AREA)
- Medicinal Chemistry (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Biophysics (AREA)
- Biochemistry (AREA)
- Genetics & Genomics (AREA)
- Gastroenterology & Hepatology (AREA)
- Molecular Biology (AREA)
- Zoology (AREA)
- Toxicology (AREA)
- General Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Pharmacology & Pharmacy (AREA)
- Animal Behavior & Ethology (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
- Peptides Or Proteins (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
Applications Claiming Priority (3)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US08/384,106 US6033847A (en) | 1995-02-06 | 1995-02-06 | InK4c-p18 and InK4d-p19, inhibitors of cyclin-dependent kinases CDK4 and CDK6, and uses thereof |
PCT/US1996/001643 WO1996024603A1 (en) | 1995-02-06 | 1996-02-06 | InK4c-p18 AND InK4D-p19, INHIBITORS OF CYCLIN-DEPEDENT KINASES CDK4 AND CDK6, AND USES THEREOF |
US384106 | 1999-08-27 |
Publications (1)
Publication Number | Publication Date |
---|---|
AU4973896A true AU4973896A (en) | 1996-08-27 |
Family
ID=23516066
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
AU49738/96A Abandoned AU4973896A (en) | 1995-02-06 | 1996-02-06 | Ink4c-p18 and ink4d-p19, inhibitors of cyclin-depedent kinases cdk4 and cdk6, and uses thereof |
Country Status (6)
Country | Link |
---|---|
US (1) | US6033847A (en) |
EP (1) | EP0808321A1 (en) |
JP (1) | JPH10513359A (en) |
AU (1) | AU4973896A (en) |
CA (1) | CA2212376A1 (en) |
WO (1) | WO1996024603A1 (en) |
Families Citing this family (24)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
NZ284612A (en) * | 1994-03-18 | 1997-09-22 | Univ Utah Res Found | Multiple tumour suppressor (mts) gene and its use in the diagnosis and treatment of cancer |
US5981702A (en) * | 1995-09-21 | 1999-11-09 | Cold Spring Harbor Laboratory | Cyclin/CDK associated proteins, and uses related thereto |
WO1998037190A1 (en) * | 1997-02-20 | 1998-08-27 | Hepavec Aktiengesellschaft Für Gentherapie | Method for induction of apoptotic cell death in malignant cells, through reduction of the rb to apoptosis inducing proteins ratio |
US6187535B1 (en) | 1998-02-18 | 2001-02-13 | Institut Pasteur | Fast and exhaustive method for selecting a prey polypeptide interacting with a bait polypeptide of interest: application to the construction of maps of interactors polypeptides |
DE19829473C2 (en) * | 1998-07-01 | 2000-08-10 | Magnus Von Knebel Doeberitz Ch | Procedure for early diagnosis of carcinomas |
US7306926B2 (en) * | 1998-07-01 | 2007-12-11 | Mtm Laboratories Ag | Method for detecting carcinomas in a solubilized cervical body sample |
AU7732900A (en) * | 1999-09-30 | 2001-04-30 | National Jewish Medical And Research Center | Method for regulating cell growth and assays related thereto |
US7306925B2 (en) * | 2001-11-09 | 2007-12-11 | Vanderbilt University | Phage antibodies to radiation-inducible neoantigens |
US7906102B2 (en) | 2001-10-03 | 2011-03-15 | Vanderbilt University | Ligands to radiation-induced molecules |
US20030216758A1 (en) * | 2001-12-28 | 2003-11-20 | Angiotech Pharmaceuticals, Inc. | Coated surgical patches |
EP1333278B1 (en) | 2002-02-01 | 2004-03-10 | MTM molecular tools in medicine | Methods for monitoring and prognosis of disease course of gastrointestinal tumors |
EP1369694A1 (en) | 2002-04-09 | 2003-12-10 | MTM Laboratories AG | Method for discrimination of metaplasias from neoplastic or preneoplastic lesions |
EP1365032B1 (en) * | 2002-05-21 | 2008-11-19 | MTM Laboratories AG | Marker molecules associated with lung tumors |
DE60200248T2 (en) * | 2002-08-01 | 2005-01-27 | Mtm Laboratories Ag | Procedure for solution-based diagnosis |
EP1422526A1 (en) * | 2002-10-28 | 2004-05-26 | MTM Laboratories AG | Method for improved diagnosis of dysplasias |
WO2004060346A2 (en) | 2002-12-30 | 2004-07-22 | Angiotech International Ag | Drug delivery from rapid gelling polymer composition |
DE60300339T2 (en) * | 2003-08-25 | 2006-04-13 | Mtm Laboratories Ag | Method for the detection of carcinomas in solubilized cervical body samples |
US7863044B2 (en) * | 2003-10-24 | 2011-01-04 | Tao Cheng | p18 in stem cell manipulations |
CN102140139B (en) * | 2010-02-03 | 2013-01-09 | 吉林大学 | Antitumor human single-chain antibody |
WO2013019730A1 (en) | 2011-07-29 | 2013-02-07 | The Washington University | Antibodies to tip-1 and grp78 |
KR20150092637A (en) | 2014-02-05 | 2015-08-13 | 삼성전자주식회사 | p16 protein variant and composition for preventing or treating a cancer containing the same |
EP3172222A4 (en) | 2014-07-24 | 2018-03-21 | Washington University | Compositions targeting radiation-induced molecules and methods of use thereof |
CN108348556A (en) * | 2015-11-02 | 2018-07-31 | 欧瑞3恩公司 | Cell-cycle arrest improves the efficiency for generating induced multi-potent stem cell |
WO2018148595A1 (en) | 2017-02-10 | 2018-08-16 | Washington University | Antibodies to tip1 and methods of use thereof |
Family Cites Families (5)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US4965188A (en) * | 1986-08-22 | 1990-10-23 | Cetus Corporation | Process for amplifying, detecting, and/or cloning nucleic acid sequences using a thermostable enzyme |
US5174986A (en) * | 1989-07-05 | 1992-12-29 | Genpharm International, Inc. | Method for determining oncogenic potential of a chemical compound |
EP0584264A1 (en) * | 1991-05-16 | 1994-03-02 | Cold Spring Harbor Laboratory | D-type cyclin and uses related thereto |
US5185260A (en) * | 1991-08-29 | 1993-02-09 | The United States Of America As Represented By The United States Department Of Energy | Method for distinguishing normal and transformed cells using G1 kinase inhibitors |
AU5549696A (en) * | 1995-04-17 | 1996-11-07 | Regents Of The University Of California, The | P19: a cell cycle inhibitor |
-
1995
- 1995-02-06 US US08/384,106 patent/US6033847A/en not_active Expired - Lifetime
-
1996
- 1996-02-06 JP JP8524400A patent/JPH10513359A/en active Pending
- 1996-02-06 WO PCT/US1996/001643 patent/WO1996024603A1/en not_active Application Discontinuation
- 1996-02-06 EP EP96906316A patent/EP0808321A1/en not_active Withdrawn
- 1996-02-06 CA CA002212376A patent/CA2212376A1/en not_active Abandoned
- 1996-02-06 AU AU49738/96A patent/AU4973896A/en not_active Abandoned
Also Published As
Publication number | Publication date |
---|---|
EP0808321A1 (en) | 1997-11-26 |
JPH10513359A (en) | 1998-12-22 |
WO1996024603A1 (en) | 1996-08-15 |
CA2212376A1 (en) | 1996-08-15 |
US6033847A (en) | 2000-03-07 |
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