AU4910179A - 2-phenyl-amino-imidazoline (2) derivatives possessing bradycardiac activity - Google Patents

2-phenyl-amino-imidazoline (2) derivatives possessing bradycardiac activity

Info

Publication number
AU4910179A
AU4910179A AU49101/79A AU4910179A AU4910179A AU 4910179 A AU4910179 A AU 4910179A AU 49101/79 A AU49101/79 A AU 49101/79A AU 4910179 A AU4910179 A AU 4910179A AU 4910179 A AU4910179 A AU 4910179A
Authority
AU
Australia
Prior art keywords
imidazoline
phenyl
amino
derivatives possessing
bradycardiac
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Abandoned
Application number
AU49101/79A
Inventor
Walter Kobinger
Herbert Koppe
Werner Kummer
Christian Lillie
Ludwig Pichler
Helmut Stahle
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Boehringer Ingelheim International GmbH
Original Assignee
CH Boehringer Sohn AG and Co KG
Boehringer Ingelheim GmbH
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by CH Boehringer Sohn AG and Co KG, Boehringer Ingelheim GmbH filed Critical CH Boehringer Sohn AG and Co KG
Publication of AU4910179A publication Critical patent/AU4910179A/en
Abandoned legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D233/00—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings
    • C07D233/04—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having one double bond between ring members or between a ring member and a non-ring member
    • C07D233/28—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having one double bond between ring members or between a ring member and a non-ring member with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D233/44—Nitrogen atoms not forming part of a nitro radical
    • C07D233/50—Nitrogen atoms not forming part of a nitro radical with carbocyclic radicals directly attached to said nitrogen atoms
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/08—Vasodilators for multiple indications
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Medicinal Chemistry (AREA)
  • Animal Behavior & Ethology (AREA)
  • Cardiology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Public Health (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Heart & Thoracic Surgery (AREA)
  • General Health & Medical Sciences (AREA)
  • Urology & Nephrology (AREA)
  • Vascular Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
AU49101/79A 1978-07-22 1979-07-20 2-phenyl-amino-imidazoline (2) derivatives possessing bradycardiac activity Abandoned AU4910179A (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
DE19782832310 DE2832310A1 (en) 1978-07-22 1978-07-22 NEW SUBSTITUTED 2-PHENYLAMINO-IMIDAZOLINE (2), THE ACID ADDITION SALTS THEREOF, THE MEDICINAL PRODUCTS CONTAINING THE SAME AND METHOD FOR THE PRODUCTION THEREOF
DE28323106 1978-07-22

Publications (1)

Publication Number Publication Date
AU4910179A true AU4910179A (en) 1980-01-31

Family

ID=6045138

Family Applications (1)

Application Number Title Priority Date Filing Date
AU49101/79A Abandoned AU4910179A (en) 1978-07-22 1979-07-20 2-phenyl-amino-imidazoline (2) derivatives possessing bradycardiac activity

Country Status (13)

Country Link
EP (1) EP0007991A1 (en)
JP (1) JPS5519272A (en)
AU (1) AU4910179A (en)
DE (1) DE2832310A1 (en)
DK (1) DK307079A (en)
ES (1) ES482742A1 (en)
FI (1) FI792275A (en)
GR (1) GR69649B (en)
IL (1) IL57854A0 (en)
NO (1) NO792406L (en)
NZ (1) NZ191067A (en)
PT (1) PT69952A (en)
ZA (1) ZA793720B (en)

Families Citing this family (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4517199A (en) * 1981-11-20 1985-05-14 Alcon Laboratories, Inc. Method for lowering intraocular pressure using phenylimino-imidazoles
US4461904A (en) * 1981-11-20 1984-07-24 Alcon Laboratories, Inc. 2-(Trisubstituted phenylimino)-imidazolines
US4644007A (en) * 1981-11-20 1987-02-17 Alcon Laboratories, Inc. 3-chloro-4-(4,5-dihydro-1H-imidazo-2-yl)-amino-5-alkylbenzoic acids, esters, salts, compositions and methods
US4515800A (en) * 1981-11-20 1985-05-07 Icilio Cavero Method of lowering intraocular pressure using phenylimino-imidazoles
US6750238B1 (en) * 2000-05-12 2004-06-15 The University Of Toledo Aralkyl ester soft drugs
US7049326B2 (en) 2000-05-12 2006-05-23 The University Of Toledo Method and compositions for temporarily incapacitating subjects

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
BE759125A (en) * 1969-11-19 1971-05-18 Boehringer Sohn Ingelheim NEW N-ALLYL-2-ARYLAMINO-IMIDAZOLINES- (2) SUBSTITUTES AND METHODS FOR MAKING THEM
DE2523103C3 (en) * 1975-05-24 1979-11-29 C.H. Boehringer Sohn, 6507 Ingelheim Substituted 2- [N-Progargyl-N- (2-chlorophenyl) amino] -imidazoline- ^), their acid addition salts, processes for their preparation and their use

Also Published As

Publication number Publication date
PT69952A (en) 1979-08-01
JPS5519272A (en) 1980-02-09
FI792275A (en) 1980-01-23
DK307079A (en) 1980-01-23
IL57854A0 (en) 1979-11-30
NO792406L (en) 1980-01-23
EP0007991A1 (en) 1980-02-20
NZ191067A (en) 1981-05-01
ZA793720B (en) 1981-03-25
DE2832310A1 (en) 1980-02-07
GR69649B (en) 1982-07-07
ES482742A1 (en) 1980-04-16

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