AU4800197A - Improved coupling activators for oligonucleotide synthesis - Google Patents

Improved coupling activators for oligonucleotide synthesis

Info

Publication number
AU4800197A
AU4800197A AU48001/97A AU4800197A AU4800197A AU 4800197 A AU4800197 A AU 4800197A AU 48001/97 A AU48001/97 A AU 48001/97A AU 4800197 A AU4800197 A AU 4800197A AU 4800197 A AU4800197 A AU 4800197A
Authority
AU
Australia
Prior art keywords
oligonucleotide synthesis
improved coupling
coupling activators
activators
improved
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Abandoned
Application number
AU48001/97A
Inventor
Jeffrey D. Carter
Wolfgang Pieken
Chandra Vargeese
John Yegge
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Nexstar Pharmaceuticals Inc
Original Assignee
Nexstar Pharmaceuticals Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Nexstar Pharmaceuticals Inc filed Critical Nexstar Pharmaceuticals Inc
Publication of AU4800197A publication Critical patent/AU4800197A/en
Abandoned legal-status Critical Current

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07HSUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
    • C07H21/00Compounds containing two or more mononucleotide units having separate phosphate or polyphosphate groups linked by saccharide radicals of nucleoside groups, e.g. nucleic acids
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07HSUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
    • C07H19/00Compounds containing a hetero ring sharing one ring hetero atom with a saccharide radical; Nucleosides; Mononucleotides; Anhydro-derivatives thereof
    • C07H19/02Compounds containing a hetero ring sharing one ring hetero atom with a saccharide radical; Nucleosides; Mononucleotides; Anhydro-derivatives thereof sharing nitrogen
    • C07H19/04Heterocyclic radicals containing only nitrogen atoms as ring hetero atom

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Biochemistry (AREA)
  • Molecular Biology (AREA)
  • Engineering & Computer Science (AREA)
  • Biotechnology (AREA)
  • General Health & Medical Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Saccharide Compounds (AREA)
AU48001/97A 1996-10-15 1997-10-08 Improved coupling activators for oligonucleotide synthesis Abandoned AU4800197A (en)

Applications Claiming Priority (5)

Application Number Priority Date Filing Date Title
US73055696A 1996-10-15 1996-10-15
US08730556 1996-10-15
US93786797A 1997-09-25 1997-09-25
US08937867 1997-09-25
PCT/US1997/015744 WO1998016540A1 (en) 1996-10-15 1997-10-08 Improved coupling activators for oligonucleotide synthesis

Publications (1)

Publication Number Publication Date
AU4800197A true AU4800197A (en) 1998-05-11

Family

ID=27112074

Family Applications (1)

Application Number Title Priority Date Filing Date
AU48001/97A Abandoned AU4800197A (en) 1996-10-15 1997-10-08 Improved coupling activators for oligonucleotide synthesis

Country Status (2)

Country Link
AU (1) AU4800197A (en)
WO (1) WO1998016540A1 (en)

Families Citing this family (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6274725B1 (en) 1998-06-02 2001-08-14 Isis Pharmaceuticals, Inc. Activators for oligonucleotide synthesis
US6300137B1 (en) * 1999-04-28 2001-10-09 Agilent Technologies Inc. Method for synthesizing a specific, surface-bound polymer uniformly over an element of a molecular array
AR036122A1 (en) * 2001-07-03 2004-08-11 Avecia Biotechnology Inc A COMPLEX OF SALT THAT INCLUDES AN N-ALQUILIMIDAZOL AND A 1,1-DIOXO-1,2-DIHIDRO-1L6-BENZO [D] -ISOTIAZOL-3-ONA AND A METHOD TO SYNTHEIZE OLIGONUCLEOTIDES USING PHOSPHORAMIDITE CHEMISTRY
US7153954B2 (en) 2001-07-12 2006-12-26 Santaris Pharma A/S Method for preparation of LNA phosphoramidites
AU2002328792A1 (en) * 2001-07-12 2003-01-29 Santaris Pharma A/S Method for preparation of lna phosphoramidites
US6894158B2 (en) 2002-02-22 2005-05-17 Honeywell International Inc. Methods of producing phosphitylated compounds
WO2019002237A1 (en) 2017-06-28 2019-01-03 Roche Innovation Center Copenhagen A/S Multiple coupling & oxidation method

Family Cites Families (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5574146A (en) * 1994-08-30 1996-11-12 Beckman Instruments, Inc. Oligonucleotide synthesis with substituted aryl carboxylic acids as activators

Also Published As

Publication number Publication date
WO1998016540A1 (en) 1998-04-23

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