AU4768193A - Test for quantitative thrombin time - Google Patents

Test for quantitative thrombin time

Info

Publication number
AU4768193A
AU4768193A AU47681/93A AU4768193A AU4768193A AU 4768193 A AU4768193 A AU 4768193A AU 47681/93 A AU47681/93 A AU 47681/93A AU 4768193 A AU4768193 A AU 4768193A AU 4768193 A AU4768193 A AU 4768193A
Authority
AU
Australia
Prior art keywords
test
thrombin time
quantitative
quantitative thrombin
time
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Abandoned
Application number
AU47681/93A
Inventor
Barbara Alving
Glenna Hendricks
Thomas Reid
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
US Department of Army
Original Assignee
US Department of Army
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from US08/021,033 external-priority patent/US5476771A/en
Application filed by US Department of Army filed Critical US Department of Army
Publication of AU4768193A publication Critical patent/AU4768193A/en
Abandoned legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/56—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving blood clotting factors, e.g. involving thrombin, thromboplastin, fibrinogen
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/81—Protease inhibitors
    • C07K14/815—Protease inhibitors from leeches, e.g. hirudin, eglin
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N2333/00—Assays involving biological materials from specific organisms or of a specific nature
    • G01N2333/81—Protease inhibitors
    • G01N2333/815—Protease inhibitors from leeches, e.g. hirudin, eglin
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N2333/00—Assays involving biological materials from specific organisms or of a specific nature
    • G01N2333/90—Enzymes; Proenzymes
    • G01N2333/914—Hydrolases (3)
    • G01N2333/948—Hydrolases (3) acting on peptide bonds (3.4)
    • G01N2333/974—Thrombin
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N2400/00—Assays, e.g. immunoassays or enzyme assays, involving carbohydrates
    • G01N2400/10—Polysaccharides, i.e. having more than five saccharide radicals attached to each other by glycosidic linkages; Derivatives thereof, e.g. ethers, esters
    • G01N2400/38—Heteroglycans, i.e. polysaccharides having more than one sugar residue in the main chain in either alternating or less regular sequence, e.g. gluco- or galactomannans, e.g. Konjac gum, Locust bean gum, Guar gum
    • G01N2400/40—Glycosaminoglycans, i.e. GAG or mucopolysaccharides, e.g. chondroitin sulfate, dermatan sulfate, hyaluronic acid, heparin, heparan sulfate, and related sulfated polysaccharides
AU47681/93A 1992-06-05 1993-06-03 Test for quantitative thrombin time Abandoned AU4768193A (en)

Applications Claiming Priority (5)

Application Number Priority Date Filing Date Title
US893631 1978-04-05
US89363192A 1992-06-05 1992-06-05
US08/021,033 US5476771A (en) 1993-02-22 1993-02-22 Test for quantitative thrombin time
US021033 1993-02-22
PCT/US1993/005315 WO1993025578A1 (en) 1992-06-05 1993-06-03 Test for quantitative thrombin time

Publications (1)

Publication Number Publication Date
AU4768193A true AU4768193A (en) 1994-01-04

Family

ID=26694177

Family Applications (2)

Application Number Title Priority Date Filing Date
AU44052/93A Abandoned AU4405293A (en) 1992-06-05 1993-06-02 Test for quantitative thrombin time
AU47681/93A Abandoned AU4768193A (en) 1992-06-05 1993-06-03 Test for quantitative thrombin time

Family Applications Before (1)

Application Number Title Priority Date Filing Date
AU44052/93A Abandoned AU4405293A (en) 1992-06-05 1993-06-02 Test for quantitative thrombin time

Country Status (5)

Country Link
EP (1) EP0643727A4 (en)
JP (1) JPH08501682A (en)
AU (2) AU4405293A (en)
CA (1) CA2137342A1 (en)
WO (2) WO1993025220A1 (en)

Families Citing this family (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6221672B1 (en) 1996-04-30 2001-04-24 Medtronic, Inc. Method for determining platelet inhibitor response
DE19781870T1 (en) * 1996-04-30 2000-02-24 Medtronic Inc Method for determining platelet inhibitor responsiveness
JP3626982B2 (en) * 1997-08-29 2005-03-09 アークレイ株式会社 Method for measuring proteolytic enzyme inhibitor and measurement kit used therefor
KR20140025303A (en) * 2010-10-01 2014-03-04 릭스하스피탈렛 Compounds capable of modulating/preserving endothelial integrity for use in prevention or treatment of acute traumatic coagulopathy and resuscitated cardiac arrest
WO2013143548A1 (en) * 2012-03-30 2013-10-03 Rigshospitalet Compounds capable of modulating/preserving endothelial integrity for use in prevention or treatment of acute traumatic coagulopathy and resuscitated cardiac arrest

Family Cites Families (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO1982001377A1 (en) * 1980-10-09 1982-04-29 Lill Helmut Method for determining a bm-antithrombin
DE3038163A1 (en) * 1980-10-09 1982-05-06 Boehringer Mannheim Gmbh, 6800 Mannheim THROMBINE INHIBITOR, ITS PRODUCTION AND USE
DE3445532A1 (en) * 1984-12-13 1986-06-19 Plantorgan Werk Heinrich G.E. Christensen, KG, 2903 Bad Zwischenahn HIRUDIN-PA, DESULFATOHIRUDINE-PA, METHOD FOR PRODUCTION AND PHARMACEUTICAL AGENTS THAT CONTAIN THESE ACTIVE SUBSTANCES
US5019393A (en) * 1988-08-03 1991-05-28 New England Deaconess Hospital Corporation Biocompatible substance with thromboresistance
US5196404B1 (en) * 1989-08-18 1996-09-10 Biogen Inc Inhibitors of thrombin
US4952562A (en) * 1989-09-29 1990-08-28 Rorer Pharmaceutical Corporation Anti-thrombotic peptides and pseudopeptides
DE59109048D1 (en) * 1990-02-14 1998-10-15 Pentapharm Ag Inhibitors for the anticoagulant pretreatment of blood samples
US5118790A (en) * 1990-07-24 1992-06-02 Sri International Analogs of hirudin

Also Published As

Publication number Publication date
CA2137342A1 (en) 1993-12-23
AU4405293A (en) 1994-01-04
WO1993025578A1 (en) 1993-12-23
WO1993025220A1 (en) 1993-12-23
EP0643727A4 (en) 1998-05-13
EP0643727A1 (en) 1995-03-22
JPH08501682A (en) 1996-02-27

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