AU476623B2 - 3 7-hydroxy-19-nor-5d-pregnane-11, 20-dione and pharmaceutical compositions thereof - Google Patents

3 7-hydroxy-19-nor-5d-pregnane-11, 20-dione and pharmaceutical compositions thereof

Info

Publication number
AU476623B2
AU476623B2 AU48754/72A AU4875472A AU476623B2 AU 476623 B2 AU476623 B2 AU 476623B2 AU 48754/72 A AU48754/72 A AU 48754/72A AU 4875472 A AU4875472 A AU 4875472A AU 476623 B2 AU476623 B2 AU 476623B2
Authority
AU
Australia
Prior art keywords
pregnane
dione
hydroxy
pharmaceutical compositions
pharmaceutical
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired
Application number
AU48754/72A
Other languages
English (en)
Other versions
AU4875472A (en
Inventor
Hanley Phillipps Leslie Stephenson Gordon
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed filed Critical
Publication of AU4875472A publication Critical patent/AU4875472A/en
Application granted granted Critical
Publication of AU476623B2 publication Critical patent/AU476623B2/en
Expired legal-status Critical Current

Links

Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/56Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids
    • A61K31/57Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids substituted in position 17 beta by a chain of two carbon atoms, e.g. pregnane or progesterone
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07JSTEROIDS
    • C07J5/00Normal steroids containing carbon, hydrogen, halogen or oxygen, substituted in position 17 beta by a chain of two carbon atoms, e.g. pregnane and substituted in position 21 by only one singly bound oxygen atom, i.e. only one oxygen bound to position 21 by a single bond
    • C07J5/0007Normal steroids containing carbon, hydrogen, halogen or oxygen, substituted in position 17 beta by a chain of two carbon atoms, e.g. pregnane and substituted in position 21 by only one singly bound oxygen atom, i.e. only one oxygen bound to position 21 by a single bond not substituted in position 17 alfa
    • C07J5/0015Normal steroids containing carbon, hydrogen, halogen or oxygen, substituted in position 17 beta by a chain of two carbon atoms, e.g. pregnane and substituted in position 21 by only one singly bound oxygen atom, i.e. only one oxygen bound to position 21 by a single bond not substituted in position 17 alfa not substituted in position 16
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07JSTEROIDS
    • C07J75/00Processes for the preparation of steroids in general
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07JSTEROIDS
    • C07J7/00Normal steroids containing carbon, hydrogen, halogen or oxygen substituted in position 17 beta by a chain of two carbon atoms
    • C07J7/0005Normal steroids containing carbon, hydrogen, halogen or oxygen substituted in position 17 beta by a chain of two carbon atoms not substituted in position 21
    • C07J7/001Normal steroids containing carbon, hydrogen, halogen or oxygen substituted in position 17 beta by a chain of two carbon atoms not substituted in position 21 substituted in position 20 by a keto group
    • C07J7/0015Normal steroids containing carbon, hydrogen, halogen or oxygen substituted in position 17 beta by a chain of two carbon atoms not substituted in position 21 substituted in position 20 by a keto group not substituted in position 17 alfa
    • C07J7/002Normal steroids containing carbon, hydrogen, halogen or oxygen substituted in position 17 beta by a chain of two carbon atoms not substituted in position 21 substituted in position 20 by a keto group not substituted in position 17 alfa not substituted in position 16

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Steroid Compounds (AREA)
AU48754/72A 1971-11-11 1972-11-10 3 7-hydroxy-19-nor-5d-pregnane-11, 20-dione and pharmaceutical compositions thereof Expired AU476623B2 (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
GB5246671A GB1409240A (en) 1971-11-11 1971-11-11 Anaesthetic steroid of the 5alpha-pregnane series

Publications (2)

Publication Number Publication Date
AU4875472A AU4875472A (en) 1974-05-16
AU476623B2 true AU476623B2 (en) 1976-09-30

Family

ID=10464023

Family Applications (1)

Application Number Title Priority Date Filing Date
AU48754/72A Expired AU476623B2 (en) 1971-11-11 1972-11-10 3 7-hydroxy-19-nor-5d-pregnane-11, 20-dione and pharmaceutical compositions thereof

Country Status (16)

Country Link
US (1) US3822297A (OSRAM)
JP (1) JPS4861465A (OSRAM)
AU (1) AU476623B2 (OSRAM)
BE (1) BE791196A (OSRAM)
CA (1) CA992068A (OSRAM)
DE (1) DE2255153A1 (OSRAM)
DK (1) DK131296B (OSRAM)
ES (1) ES408509A1 (OSRAM)
FR (1) FR2159447B1 (OSRAM)
GB (1) GB1409240A (OSRAM)
IE (1) IE37076B1 (OSRAM)
IL (1) IL40790A (OSRAM)
NL (1) NL7215225A (OSRAM)
PH (1) PH9928A (OSRAM)
SE (1) SE390025B (OSRAM)
ZA (1) ZA727971B (OSRAM)

Families Citing this family (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3952031A (en) * 1970-11-12 1976-04-20 Glaxo Laboratories Limited Anaesthetic composition containing a steroid of the 5α-pregnane series and method of using same
DE2438020A1 (de) * 1974-08-05 1976-02-26 Schering Ag 18-methyl-19-nor-20-keto-pregnane und verfahren zu ihrer herstellung
US5232917A (en) * 1987-08-25 1993-08-03 University Of Southern California Methods, compositions, and compounds for allosteric modulation of the GABA receptor by members of the androstane and pregnane series
AUPN498095A0 (en) * 1995-08-23 1995-09-14 Goodchild, Colin Stanley Compounds and compositions
US6787530B1 (en) 1996-08-23 2004-09-07 Monash University Use of pregnane-diones as analgesic agents

Family Cites Families (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR1281205A (fr) * 1956-12-21 1962-01-12 Organon Nv Procédé d'obtention de composés de la série du prégnane

Also Published As

Publication number Publication date
ZA727971B (en) 1973-09-26
DK131296B (da) 1975-06-23
CA992068A (en) 1976-06-29
US3822297A (en) 1974-07-02
FR2159447A1 (OSRAM) 1973-06-22
FR2159447B1 (OSRAM) 1976-08-20
IL40790A0 (en) 1973-01-30
GB1409240A (en) 1975-10-08
DK131296C (OSRAM) 1975-11-17
IL40790A (en) 1975-05-22
JPS4861465A (OSRAM) 1973-08-28
DE2255153A1 (de) 1973-05-24
PH9928A (en) 1976-06-14
IE37076L (en) 1973-05-11
NL7215225A (OSRAM) 1973-05-15
BE791196A (fr) 1973-05-10
IE37076B1 (en) 1977-04-27
AU4875472A (en) 1974-05-16
SE390025B (sv) 1976-11-29
ES408509A1 (es) 1976-05-01

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